1. Articles from Yuhong Gan

    1-4 of 4
    1. Detection of pachychoroid neovasculopathy with optical coherence tomography angiography versus dye angiography imaging

      Detection of pachychoroid neovasculopathy with optical coherence tomography angiography versus dye angiography imaging

      Background: To investigate the sensitivity and specificity of optical coherence tomography angiography (OCTA) versus dye angiography for detecting pachychoroid neovasculopathy (PNV) and to determine the morphological factors that affect PNV detection. Methods: Patients with pachychoroid phenotype wereprospectively enrolled and underwent multimodal imaging examinations during the same visit. The diagnostic accuracy of fundus fluorescein angiography (FFA), FFA combined with indocyanine green angiography (ICGA) and OCTA for PNV was evaluated using multimodal imaging as the reference. Multimodal parameters of PNV were qualitatively and quantitatively assessed. Results: PNV was detected in 58 eyes (46 patients) out of 340 pachychoroid eyes (201 patients) according ...

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    2. Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography

      Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography

      Purpose: To investigate the clinical features of a macrophage-like cell (MLC) obtained by en face optical coherence tomography (OCT) in retinal vein occlusion (RVO). Methods: The study involved 36 patients with treatment-naïve unilateral acute RVO, including 21 branch RVO (BRVO) and 15 central RVO. Vessel density and macular thickness were quantified using OCT angiography. A 3-μm en face OCT slab on the inner limiting membrane in the optic nerve head (ONH) region or macular region was used to visualize the MLCs. The MLCs were binarized and quantified using a semiautomated method. The unaffected fellow eyes served as the ...

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    3. OCTA versus dye angiography for the diagnosis and evaluation of neovascularisation in punctate inner choroidopathy

      OCTA versus dye angiography for the diagnosis and evaluation of neovascularisation in punctate inner choroidopathy

      Purpose: To compare the sensitivity and specificity of identifying and evaluating the choroidal neovascularisation (CNV) in punctate inner choroidopathy (PIC) by optical coherence tomography angiography (OCTA) versus dye angiography. Methods: Consecutive patients diagnosed with PIC were enrolled in this study from June 2016 to December 2019. During the same visit, each patient underwent comprehensive ophthalmological and multimodal imaging examinations. The diagnostic accuracy of different modalities was evaluated. Results: The study included 160 affected eyes from 123 patients. Ninety-five eyes (59.38%) were identified with secondary CNV by multimodal imaging. The sensitivity and specificity for CNV detection with OCTA alone were ...

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    4. Retinal pigment epithelium hyperplasia overlying pigment epithelial detachment in age-related macular degeneration can masquerade as neovascularization on optical coherence tomography angiography

      Retinal pigment epithelium hyperplasia overlying pigment epithelial detachment in age-related macular degeneration can masquerade as neovascularization on optical coherence tomography angiography

      Purpose To report the image artifacts due to retinal pigment epithelium (RPE) hyperplasia overlying retinal pigment epithelial detachment (PED) in age-related macular degeneration (AMD), which can masquerade as neovascularization on optical coherence tomography angiography (OCTA). Methods A hospital-based, retrospective, and cross-sectional study. Twenty-two eyes from 16 patients with non-vascularized PED related to AMD were included in this study. All patients were examined by OCTA, spectral-domain optical coherence tomography, fluorescence angiography, and indocyanine green angiography. Vascular flow signals (VFS) on both the outer retinal slab of en face OCTA and cross-sectional OCTA and their correspondence with RPE hyperplasia were evaluated. Results ...

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    1-4 of 4
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    Retinal pigment epithelium hyperplasia overlying pigment epithelial detachment in age-related macular degeneration can masquerade as neovascularization on optical coherence tomography angiography OCTA versus dye angiography for the diagnosis and evaluation of neovascularisation in punctate inner choroidopathy Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography Detection of pachychoroid neovasculopathy with optical coherence tomography angiography versus dye angiography imaging Asynchronous feature regularization and cross-modal distillation for OCT based glaucoma diagnosis Developments and Clinical Applications of Noninvasive Optical Technologies for Skin Cancer Diagnosis Retinal Pigment Epithelial Changes in Parkinson's Disease: A Spectral Domain Optical Coherence Tomography Study Prognostic Features of Preoperative Optical Coherence Tomography in Retinal Detachments: A systematic review and meta-analysis Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model Coronary plaque characterization assessed by delayed enhancement dual-layer spectral CT angiography and optical coherence tomography Use of multimodal dataset in AI for detecting glaucoma based on fundus photographs assessed with OCT: focus group study on high prevalence of myopia Distinctive Morphological Patterns of Complicated Coronary Plaques in Acute Coronary Syndromes: Insights from an Optical Coherence Tomography Study