1. Articles from Peng Gao

    1-5 of 5
    1. Fundus Changes Evaluated by OCTA in Patients With Cerebral Small Vessel Disease and Their Correlations: A Cross-Sectional Study

      Fundus Changes Evaluated by OCTA in Patients With Cerebral Small Vessel Disease and Their Correlations: A Cross-Sectional Study

      Objective: To detect fundus changes in patients with cerebral small vessel disease (CSVD) using optical coherence tomography angiography (OCTA) and to investigate the correlations between CSVD and fundus changes. Methods: From January 2019 to January 2020, patients diagnosed with CSVD by magnetic resonance imaging (MRI) were enrolled in our study and received fundus examinations using OCTA. CSVD was defined as white matter hyperintensities, enlarged perivascular spaces, lacunes, or microbleeds on MRI. OCTA parameters included foveal avascular zone areas, retinal nerve fiber layer thickness, and capillary densities of the superficial retinal capillary plexuses, deep retinal capillary plexuses, and the radial peripapillary ...

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    2. Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience

      Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience

      Background: Despite advances in non-invasive imaging, the characterization of atherosclerotic plaque remains superior with frequency-domain optical coherence tomography (FD-OCT) in the clinical coronary and experimental cerebrovascular literature. An assessment of the feasibility and safety of FD-OCT for intracranial atherosclerotic stenosis (ICAS) is desirable. Methods: We analyzed a cohort of all consecutive FD-OCT evaluations for ICAS performed at our institution from April 2017 to August 2018 (16 months) in patients who suffered from transient ischemic attack (TIA) or non-disabling stroke despite optimal medical management within 90 days of admission attributable to angiographically verified 70-99% stenosis of an intracranial artery. Results: Thirty-three ...

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    3. Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography

      Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography

      Background: Intracranial vertebral artery (V4 segment) stenosis quantification traditionally uses the narrowest stenosis diameter. However, the stenotic V4 lumen is commonly irregularly shaped. Optical coherence tomography (OCT) allows a more precise calculation of V4 geometry. We compared the narrowest diameter stenosis (DS), measured by digital subtraction angiography (DSA), with the area stenosis (AS), measured by OCT. We hypothesized that DS is the gold standard for measuring the degree of stenosis. Methods: Five neuroradiologists evaluated 49 stenosed V4 segments in a blinded protocol. V4 stenosis was measured in millimeters on DSA at its narrowest diameter. OCT was used to estimate the ...

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    4. Structure-Aware Noise Reduction Generative Adversarial Network for Optical Coherence Tomography Image

      Structure-Aware Noise Reduction Generative Adversarial Network for Optical Coherence Tomography Image

      Optical coherence tomography (OCT) is a common imaging examination in ophthalmology, which can visualize cross-sectional retinal structures for diagnosis. However, image quality still suffers from speckle noise and other motion artifacts. An effective OCT denoising method is needed to ensure the image is interpreted correctly. However, lack of paired clean image restricts its development. Here, we propose an end-to-end structure-aware noise reduction generative adversarial network (SNR-GAN), trained with un-paired OCT images. The network is designed to translate images between noisy domain and clean domain. Besides adversarial and cycle consistence loss, structure-aware loss based on structural similarity index (SSIM) is added ...

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    5. Optical coherence tomography of spontaneous basilar artery dissection in a patient with acute ischemic stroke

      Optical coherence tomography of spontaneous basilar artery dissection in a patient with acute ischemic stroke

      The diagnosis of intracranial arterial dissection (IAD) may be challenging and multimodal imaging techniques are often needed to confirm the diagnosis. Previous studies have based their criteria for diagnosis of IAD on conventional angiography, computed tomography or magnetic resonance imaging. We report a case with acute ischemic stroke due to spontaneous basilar artery dissection in which intravascular optical coherence tomography (OCT) was used to show features of IAD. A 59-year-old woman presented with symptoms of acute ischemic stroke. Thrombosis related to basilar artery (BA) stenosis was assumed on conventional angiography; however, no clot was retrieved after mechanical thrombectomy (MT) and ...

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    1-5 of 5
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  2. Topics in the News

    1. (3 articles) Capital Medical University
    2. (1 articles) Harvard University
    3. (1 articles) Brigham and Women’s Hospital
    4. (1 articles) Abbott
    5. (1 articles) Cardiovascular Research Foundation
    6. (1 articles) UC Davis
    7. (1 articles) University of Pittsburgh
    8. (1 articles) Capital Medical University
    9. (1 articles) Tianjin University
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    12. (1 articles) Forssmann
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    Optical coherence tomography of spontaneous basilar artery dissection in a patient with acute ischemic stroke Structure-Aware Noise Reduction Generative Adversarial Network for Optical Coherence Tomography Image Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience Fundus Changes Evaluated by OCTA in Patients With Cerebral Small Vessel Disease and Their Correlations: A Cross-Sectional Study Macular and choroidal perfusion using optical coherence tomography angiography in type-2 diabetic patients without diabetic retinopathy Short-term evaluation of clear corneal incision after phacoemulsification using anterior segment optical coherence tomography Evaluation of the central vault following implantable phakic contact lens and its correlation to horizontal white to white corneal diameter by anterior segment optical coherence tomography Automatic bifurcation detection utilizing pullback characteristics of bifurcation in intravascular optical coherence tomography An IoT based predictive modeling for Glaucoma detection in optical coherence tomography images using hybrid genetic algorithm The Value of Optical Coherence Tomography Angiography in Pituitary Adenomas Effectiveness of optical coherence tomography angiography (OCT-A) in staging glaucoma