1. Articles from Adrian Wong

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    1. Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis

      Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis

      Topic Optical coherence tomography (OCT) is a non-invasive tool to measure specific retinal layers in the eye. The relationship of retinal spectral domain-OCT (SD-OCT) measurements with Alzheimer’s Disease (AD) and mild cognitive impairment (MCI) remains unclear. Hence, we conducted a systematic review and meta-analysis to examine the SD-OCT measurements in AD and MCI. Clinical Relevance Current methods of diagnosing early AD are expensive and invasive. Retinal measurements of SD-OCT, which are non-invasive, technically simple and inexpensive, are potential biomarkers of AD. Methods We conducted a literature search in PubMed and EMBASE to identify studies published before 31 December 2017 ...

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    1. (1 articles) The Chinese University of Hong Kong
    2. (1 articles) Singapore Eye Research Institute
    3. (1 articles) Erasmus University
    4. (1 articles) National University of Singapore
    5. (1 articles) Tien Yin Wong
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