1. Articles from Clement C. Tham

    1-3 of 3
    1. Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis

      Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis

      Topic Optical coherence tomography (OCT) is a non-invasive tool to measure specific retinal layers in the eye. The relationship of retinal spectral domain-OCT (SD-OCT) measurements with Alzheimer’s Disease (AD) and mild cognitive impairment (MCI) remains unclear. Hence, we conducted a systematic review and meta-analysis to examine the SD-OCT measurements in AD and MCI. Clinical Relevance Current methods of diagnosing early AD are expensive and invasive. Retinal measurements of SD-OCT, which are non-invasive, technically simple and inexpensive, are potential biomarkers of AD. Methods We conducted a literature search in PubMed and EMBASE to identify studies published before 31 December 2017 ...

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    2. Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study

      Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study

      Aims To evaluate the distributions of quantitative optical coherence tomography angiography (OCT-A) metrics and its associated factors in children. Methods 1059 children aged 6–8 years were recruited from the Hong Kong Children Eye Study. All the participants underwent OCT-A with a swept-source OCT. Retinal microvasculature on superficial capillary plexus was assessed and quantified by a customised automated image analysis programme. Univariable and multiple linear regression analyses were performed to determine systemic (body mass index (BMI), waist circumference, head circumference and blood pressure), demographic and ocular (axial length (AL), macular thickness and volume, retinal nerve fibre layer (RNFL) thickness and ...

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    3. Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study

      Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study

      Aim To examine the correlation of best-corrected visual acuity (BCVA) with intercapillary area (ICA) measured from optical coherence tomography angiography (OCT-A) in patients with diabetes, and to compare the strength of associations between BCVA with ICA and other OCT-A metrics. Methods A cross-sectional study involved 447 eyes from 299 patients with diabetes. All participants underwent OCT-A with a swept-source OCT (Triton DRI-OCT, Topcon, Tokyo, Japan). An automated customised MATLAB programme was used to quantify ICA (the mean of the 10 largest areas including foveal avascular zone (FAZ) area (ICA10_FAZ) and excluding FAZ area (ICA10_excFAZ)) and other OCT-A metrics (FAZ area ...

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    1-3 of 3
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    1. (3 articles) The Chinese University of Hong Kong
    2. (1 articles) Singapore Eye Research Institute
    3. (1 articles) Erasmus University
    4. (1 articles) National University of Singapore
    5. (1 articles) Tien Yin Wong
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    Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis Optical coherence tomography imaging in keratoconus https://doi.org/10.1111/cxo.12880 Bacillary layer detachment: a novel optical coherence tomography finding as part of blunt eye trauma Remineralizing Potential of Nano-Silver-Fluoride for Tooth Enamel: An Optical Coherence Tomography Analysis Clinical Features and Multi-Modality Imaging of Isolated Retinal Astrocytic Hamartoma Choroidal Vascularity Index Using Swept-Source and Spectral-Domain Optical Coherence Tomography: A Comparative Study Evaluation of equine corneal disease using spectral domain optical coherence tomography (SD‐OCT) Attention to Lesion: Lesion-Aware Convolutional Neural Network for Retinal Optical Coherence Tomography Image Classification BiOS Hot Topics: Changing of the Guard