1. Articles from Jason M. Zara

    1-4 of 4
    1. Development of novel imaging probe for optical∕acoustic radiation imaging (OARI)

      Development of novel imaging probe for optical∕acoustic radiation imaging (OARI)

      Purpose: Optical/acoustic radiation imaging (OARI) is a novel imaging modality being developed to interrogate the optical and mechanical properties of soft tissues. OARI uses acoustic radiation force to generate displacement in soft tissue. Optical images before and after the application of the force are used to generate displacement maps that provide information about the mechanical properties of the tissue under interrogation. Since the images are optical images, they also represent the optical properties of the tissue as well. In this paper, the authors present the first imaging probe that uses acoustic radiation force in conjunction with optical coherence tomography ...

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    2. Tissue-mimicking bladder wall phantoms for evaluating acoustic radiation force-optical coherence elastography systems

      Tissue-mimicking bladder wall phantoms for evaluating acoustic radiation force-optical coherence elastography systems
      Purpose: Acoustic radiation force–optical coherence elastography (ARF-OCE) systems are novel imaging systems that have the potential to simultaneously quantify and characterize the optical and mechanical properties of in vivo tissues. This article presents the construction of bladder wall phantoms for use in ARF-OCE systems. Mechanical, acoustic, and optical properties are reported and compared to published values for the urinary bladder. Methods: The phantom consisted of 0.2000±0.0089 and 6.0000±0.2830 µm polystyrene microspheres (Polysciences Inc., Warrington, PA, Catalog Nos. 07304 and 07312), 7.5±1.5 µm copolymer microspheres composed of acrylonitrile and vinylidene chloride ...
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    3. Wavelet analysis enables system-independent texture analysis of optical coherence tomography images

      Texture analysis for tissue characterization is a current area of optical coherence tomography (OCT) research. We discuss some of the differences between OCT systems and the effects those differences have on the resulting images and subsequent image analysis. In addition, as an example, two algorithms for the automatic recognition of bladder cancer are compared: one that was developed on a single system with no consideration for system differences, and one that was developed to address the issues associated with system differences. The first algorithm had a sensitivity of 73% and specificity of 69% when tested using leave-one-out cross-validation on data ...
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    4. Computer recognition of cancer in the urinary bladder using optical coherence tomography and texture analysis

      Colleen A. Lingley-Papadopoulos, Murray H. Loew, Michael J. Manyak et al. The vast majority of bladder cancers originate within 600 [mu]m of the tissue surface, making optical coherence tomography (OCT) a potentially powerful tool for recognizing cancers that are not easily visible with current techniques. OCT is a new technology, however, and surgeons are not familiar w ... [J. Biomed. Opt. 13, 024003 (2008)] published Mon Apr 14, 2008.
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    1-4 of 4
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    1. (4 articles) George Washington University
    2. (4 articles) Jason M. Zara
    3. (1 articles) Washington University in St. Louis
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