1. Articles from Junxiao Yu

    1-5 of 5
    1. Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series

      Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series

      Alopecia areata (AA) is an autoimmune hair loss condition that is difficult to treat and frequently disruptive to the psychosocial well-being of patients. Platelet-rich plasma (PRP) is an innovative therapy that provides concentrated GFs that impart anti-inflammatory effects. Optical coherence tomography (OCT) is a noninvasive imaging modality with the potential for providing quantitative monitoring of AA response to PRP. Our objective is to share our experience using OCT to monitor the therapeutic progress of patients with AA treated with PRP. Two patients with patchy AA and one with alopecia universalis were treated with PRP three times at 6-week intervals as ...

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    2. The effect of melanin on in vivo optical coherence tomography of the skin in a multiethnic cohort

      The effect of melanin on in vivo optical coherence tomography of the skin in a multiethnic cohort

      Background Noninvasive real‐time assessment of living tissue is quickly becoming invaluable for bolstering histologic and dermatoscopic measures of cutaneous conditions. While many skin researchers have explored the utility of noninvasive imaging in inflammatory and malignant skin conditions, there is yet to be a definitive and direct assessment of the effects of melanin on the quality of optical coherence tomography (OCT) imaging and its accuracy in multiethnic patient populations. We conducted a study to evaluate the effects of melanin on the quality of in vivo OCT imaging. Methods Volunteers of all Fitzpatrick skin types were imaged once in five skin ...

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      Mentions: UC Irvine
    3. Optical Coherence Tomography as an Oral Cancer Screening Adjunct in a Low Resource Settings

      Optical Coherence Tomography as an Oral Cancer Screening Adjunct in a Low Resource Settings

      Oral cancer is the sixth most common cancer worldwide, predominantly seen in low and middle-income countries (LMIC). Two thirds of all cases are detected at a late stage when prognosis and treatment outcomes are poor. Oral lesions are commonly detected by visual inspection, followed by invasive surgical biopsy and time consuming histopathological analysis. Optical Coherence Tomography (OCT), a minimally invasive tomographic imaging technology, can be used to non-invasively identify premalignant or malignant change in the oral mucosa. In this study, a mobile OCT imaging system was designed, constructed and tested for its performance as a point-of-care oral diagnostic device. Twenty ...

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      Mentions: UC Irvine
    4. Viscosity monitoring during hemodiluted blood coagulation using optical coherence elastography

      Viscosity monitoring during hemodiluted blood coagulation using optical coherence elastography

      Rapid and accurate clot diagnostic systems are needed for the assessment of hemodiluted blood coagulation. We develop a real-time optical coherence elastography (OCE) system, which measures the attenuation coefficient of a compressional wave induced by a piezoelectric transducer (PZT) in a drop of blood using optical coherence tomography (OCT), for the determination of viscous properties during the dynamic whole blood coagulation process. Changes in the viscous properties increase the attenuation coefficient of the sample. Consequently, dynamic blood coagulation status can be monitored by relating changes of the attenuation coefficient to clinically relevant coagulation metrics, including the initial coagulation time and ...

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    5. Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature

      Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature

      Endoscopic imaging technologies, such as endoscopic optical coherence tomography (OCT) and near-infrared fluorescence, have been used to investigate vascular and morphological changes as hallmarks of early cancer in the gastrointestinal tract. Here we developed a high-speed multimodality endoscopic OCT and fluorescence imaging system. Using this system, the architectural morphology and vasculature of the rectum wall were obtained simultaneously from a Sprague Dawley rat in vivo . This multimodality imaging strategy in a single imaging system permits the use of a single imaging probe, thereby improving prognosis by early detection and reducing costs.

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      Mentions: UC Irvine
    1-5 of 5
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  2. Topics in the News

    1. (4 articles) UC Irvine
    2. (2 articles) Duke University
    3. (1 articles) Zhejiang University
    4. (1 articles) Konyang University
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    Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature Viscosity monitoring during hemodiluted blood coagulation using optical coherence elastography Optical Coherence Tomography as an Oral Cancer Screening Adjunct in a Low Resource Settings The effect of melanin on in vivo optical coherence tomography of the skin in a multiethnic cohort Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series Repeatability of Optical Coherence Tomography Angiography Measurements in Patients with Retinal Vein Occlusion Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study Anterior‐segment optical coherence tomography of filtering blebs in the early postoperative period of ab externo SIBS microshunt implantation with mitomycin C: Morphological analysis and correlation with intraocular pressure reduction Combining artificial intelligence and robotics: a novel fully automated optical coherence tomography-based approach for eye disease screening Impact of fundus pigmentation on retinal layer visibility on investigational bedside optical coherence tomography in preterm infants Vascular morphology in facial solar lentigo assessed by optical coherence tomography angiography Macular vascular changes in pregnant women with gestational diabetes mellitus by optical coherence tomography angiography