1. Articles from Ruchit Shah

    1-3 of 3
    1. Comparison of Normal Skin and Thermal and Chemical Burn Wounds using Vibrational Optical Coherence Tomography

      Comparison of Normal Skin and Thermal and Chemical Burn Wounds using Vibrational Optical Coherence Tomography

      he search for methods to evaluate the extent and severity of skin lesions, such as burns and other skin disorders, has been a subject of extentive research. While suction testing, elastography and other tests can be done noninvasively on intact skin, these tests cannot be done on burns and open wounds due to the possible injury that may occur. In addition, they fail to yield comparable results obtained using destructive tests such as uniaxial tensile testing. We have developed a technique to combine optical coherence tomography (OCT) with vibrational analysis (VOCT) to non-invasively and non-destructively evaluate the properties of skin ...

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      Mentions: Lumedica
    2. Biomechanical Relationship Between Cells and Collagen in Skin and Skin Lesions

      Biomechanical Relationship Between Cells and Collagen in Skin and Skin Lesions

      We have used vibrational optical coherence tomography to study the relationship between cellular and collagen mechanical behavior in skin in-vivo. Quantitative measurements of the cellular and collagen resonant frequencies and peak heights were used to calculate the moduli and relative contribution of cells and collagen to the mechanical behavior of skin. Our results suggest that the resonant frequencies measured in vascularized skin are increased by arterial blood flow and is hypothesized to be a result of upregulation of mechanotransduction. The increased cell contribution to the pixel intensity and an increased resonant frequency peak height, suggests that arterial flow influences the ...

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    3. Non-destructive biomechanical testing of tissues using a vibrational optical coherence tomography setup (Thesis)

      Non-destructive biomechanical testing of tissues using a vibrational optical coherence tomography setup (Thesis)

      The mechanical properties of tissues and implants contribute to their physiological functionality, and have been vast areas of research in fields such as Dermatology, Cardiology, Neurology, Ophthalmology, Orthopedics and Urology. Several tests and modalities have been used to measure the mechanical properties of tissues and implants including tensile, compressive, shear, and bending in one or more axial directions. However, majority of these tests are destructive, rendering the material unusable post-testing; whereas most of the non-destructive imaging modalities such as magnetic resonance imaging (MRI), nuclear magnetic resonance (NMR) and ultrasound are costly and have lower spatial resolution. Optical coherence tomography (OCT ...

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    1-3 of 3
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    1. (1 articles) Lumedica
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    Non-destructive biomechanical testing of tissues using a vibrational optical coherence tomography setup (Thesis) Biomechanical Relationship Between Cells and Collagen in Skin and Skin Lesions Comparison of Normal Skin and Thermal and Chemical Burn Wounds using Vibrational Optical Coherence Tomography A PhD position is available in OPIRA laboratory at the Biomedical Engineering Department of the University of Illinois in Chicago A PhD position is available in OPIRA laboratory at the Biomedical Engineering Department of the University of Illinois in Chicago Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Neuroretinal Rim Thickness Using Spectral-Domain Optical Coherence Tomography Development of Deep Learning Models to Predict Best-Corrected Visual Acuity from Optical Coherence Tomography Machine learning helps improve diagnostic ability of subclinical keratoconus using Scheimpflug and OCT imaging modalities Applications and Future Directions for Optical Coherence Tomography in Dermatology Anterior Segment Inflammation in Pediatric Uveitis Is Associated with Reduced Retinal Vascular Density as Quantified by Optical Coherence Tomography Angiography Neointima characteristics as a prognostic marker for drug-coated balloon angioplasty in patients with in-stent restenosis: an optical coherence tomography study Using Anterior Segment Optical Coherence Tomography (ASOCT) Parameters to Determine Pupillary Block versus Plateau Iris Configuration