1. Articles from UH_News

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    1. New technology could improve LASIK surgery, eye disease detection

      New technology could improve LASIK surgery, eye disease detection

      ASIK eye surgery - a laser reshaping of the cornea to improve vision - is one of the most popular elective surgeries in the United States, and a University of Houston professor of biomedical engineering intends to improve upon it by giving surgeons more information about the cornea before they begin. Specifically, Kirill Larin wants to provide measurement of corneal elasticity, a key component of visual acuity. Eye surgeons currently do not have a reliable method to perform a quantitative measurement of corneal elasticity in patients before the procedure. "We will develop a novel method for the imaging and assessment of corneal ...

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    2. Does cannabis use amplify the effect of prenatal alcohol exposure and vice versa?

      Does cannabis use amplify the effect of prenatal alcohol exposure and vice versa?

      An unforeseen consequence of normalization of marijuana use is that adolescents and adults of childbearing age are increasingly engaged in a practice of Simultaneous Alcohol and Cannabinoid (SAC) use, or co-ingestion. A recent U.S. hospital-based assessment revealed that at the time of birth, about 22% of assessed umbilical cords were positive for marijuana. "It is likely, given the documented synergy between ethanol and cannabinoids, that their combined ingestion will, as hypothesized, result in increased neurogenic and neurovascular deficits in exposed offspring," said Kirill Larin, University of Houston professor of biomedical engineering. Larin and collaborator Rajesh Miranda of Texas A ...

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    3. Understanding congenital heart defects to prevent them

      Understanding congenital heart defects to prevent them

      To understand cardiovascular failures, the leading cause of birth defect-related deaths in infants, UH professor of biomedical engineering Kirill Larin is teaming up with Baylor College of Medicine professor of cellular and molecular physiology Irina Larina on a chicken and egg hunt. "When the heart develops, it becomes stiffer as required for ability to contract and pump blood," said Larin. "So the question is - does it become stiff because it's contracting, or is it stiff to begin with because it is genetically predefined?" Surprisingly, very little is known about an embryo's developing heart. "Defining how these mechanical factors ...

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    4. Watching an embryo's neural tube close

      Watching an embryo's neural tube close

      In those precious weeks before a woman even realizes she's pregnant, an embryo will have already developed a neural tube, a hollow structure made of cells which will eventually become the brain and spinal cord. Now, with $3.2 million from the National Institutes of Health, UH professor of biomedical engineering Kirill Larin will tackle the evolutionary anomaly of why the neural tube closes in most embryos but remains open in others, leading to birth defects such as spina bifida and anencephaly. Neural Tube Defects (NTD) are the second most common structural birth defect in humans, affecting upwards of ...

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    5. UH optometrist investigates changes in eye structure in astronauts

      UH optometrist investigates changes in eye structure in astronauts

      Astronauts who spend time aboard the International Space Station return to Earth with changes to the structure of their eyes which could impact their vision. NASA has studied the phenomenon, known as space flight-associated neuro-ocular syndrome (SANS), for several years, and now a University of Houston optometrist has quantified some of the changes using optical coherence tomography imaging, reporting his findings in JAMA Ophthalmology . "We studied pre-flight and post-flight data from 15 astronauts who had spent time aboard the space station and detected changes in morphology of the eyes," said Nimesh Patel, assistant professor. All of them had good vision ...

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    UH optometrist investigates changes in eye structure in astronauts Watching an embryo's neural tube close Understanding congenital heart defects to prevent them Does cannabis use amplify the effect of prenatal alcohol exposure and vice versa? New technology could improve LASIK surgery, eye disease detection Precision of attenuation coefficient measurements by optical coherence tomography Machine learning classification of multiple sclerosis in children using optical coherence tomography Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery Duke University Receives NIH Grant for OCTA and Glaucoma Progression in the Non-Human Primate University of Alabama at Birmingham Receives NIH Grant for Development of a supercontinuum laser source interferometer with sub-micron resolution to understand tear film structure and function in dry eye disease Massachusetts General Hosptial Receives NIH Grant for Intravascular microstructural, chemical and biomechanical characterization of coronary plaques Theia Imaging, LLD Receives NIH Grant for A Widefield, Handheld OCT system for Patients who are Unable to Cooperate