1. Articles from N. N. Karyakin

    1-2 of 2
    1. Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Determining boundaries of infiltrative glial tumors remains a challenging problem in neurooncology. Optical coherence tomography (OCT) with cross-polarization (CP) visualization is a promising technique as a surgical guidance tool. However, the outcome of the procedures performed under OCT guidance strongly depends on the surgeon’s qualification. Thus, a quantitative method for assessing resection margins with OCT is required. The aim of this study was to develop a robust quantitative approach for CP OCT data to differentiate tumorous from non-tumorous tissues in a rat glioma model. Materials and Methods. The study was carried out on the rats’ brains (n=6) with ...

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    2. Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      The aim of the study was to provide visual and quantitative evaluation of tumorous and normal brain tissue images obtained by cross-polarization optical coherence tomography (CP OCT) in a comparative in vivo and ex vivo study. Materials and Methods. The CP OCT as a non-damaging noninvasive optical method for tissue structure imaging was used in the study. It enables obtaining volumetric images of 2.4×2.4×1.25 mm 3 in size in real time within a short time of 26 s. The objects were tumorous and normal brain tissues of 12 experimental animals (Wistar rats): 4 — intact, 4 ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Institute of Applied Physics
    2. (2 articles) Elena B. Kiseleva
    3. (2 articles) Natalia D. Gladkova
    4. (2 articles) Carl Zeiss Meditec
    5. (1 articles) University of Toronto
    6. (1 articles) Nizhny Novgorod State Medical Academy
    7. (1 articles) Grigory V. Gelikonov
    8. (1 articles) I. Alex Vitkin
    9. (1 articles) University of Missouri
    10. (1 articles) Johns Hopkins University
    11. (1 articles) Technical University of Munich
    12. (1 articles) UCSD
    13. (1 articles) University of Cambridge
    14. (1 articles) University of Rochester
    15. (1 articles) Gang Yao
    16. (1 articles) Taiji Sakamoto
    17. (1 articles) Heidelberg Engineering
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