1. Articles from Hui Dong

    1-4 of 4
    1. Relationship between elevated plasma ceramides and plaque rupture in patients with ST-segment elevation myocardial infarction

      Relationship between elevated plasma ceramides and plaque rupture in patients with ST-segment elevation myocardial infarction

      Background and aims Ceramides (Cer) is an atherogenic substance. However, the associations between specific plasma Cer levels and culprit plaque morphology in ST-segment elevation myocardial infarction (STEMI) patients are unclear. Methods The study consisted of two parallel cohorts. 100 consecutive patients with STEMI were screened as discovery cohort. In the validation cohort, we separately screened 30 normal donors, 30 stable angina pectoris (SAP) and 315 STEMI patients. All STEMI patients underwent emergency percutaneous intervention (PCI) and optical coherence tomography (OCT) examination for culprit plaque. Based on established diagnostic criteria, STEMI patients were classified into plaque rupture (PR) and plaque erosion ...

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      Mentions: Bo Yu
    2. Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography

      Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography

      Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic links to development of atherosclerosis and are related to major adverse cardiovascular events (MACEs). Previous researches have demonstrated vulnerable plaques contribute to acute cardiovascular events and poor prognosis. This study aimed to explore the associations between Cer and culprit plaque characterizations evaluated by optical coherence tomography (OCT). It was found that plasma Cer are associated with culprit plaque vulnerability evaluated by OCT, providing evidence supporting proatherogenic roles and potential to act as markers for plaque vulnerability of Cer.

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    3. Impact of vessel curvature on neointimal healing after stent implantation as assessed by optical coherence tomography

      Impact of vessel curvature on neointimal healing after stent implantation as assessed by optical coherence tomography

      Purpose: Previous studies have indicated that stent implantation could alter the vessel geometry, which may impact the neointimal healing process. Curvature is an important parameter for evaluating vessel geometry. The purpose of our study was to investigate the relationship between vessel curvature and neointimal healing after stent implantation. Methods: Fifty-nine patients with acute coronary syndrome (ACS) who underwent stent implantation were enrolled in the study. According to the post-percutaneous coronary intervention vessel curvature measured by quantitative coronary angiography, patients were divided into high (n = 30) and low (n = 29) curvature groups. Neointimal thickness and area together with the neointimal type ...

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    4. Culprit plaque characteristics in women vs men with a first ST-segment elevation myocardial infarction: In vivo optical coherence tomography insights

      Culprit plaque characteristics in women vs men with a first ST-segment elevation myocardial infarction: In vivo optical coherence tomography insights

      Background It is unclear whether more severe coronary atherosclerosis is a prerequisite to an initial acute coronary event in women vs men. Hypothesis Women may have more severe coronary atherosclerosis than men in patients with acute coronary event. Methods We used intravascular optical coherence tomography (OCT) to evaluate gender differences in culprit-plaque morphology in patients with a first ST-segment elevation myocardial infarction (STEMI).We retrospectively enrolled 211 consecutive patients who experienced a first STEMI and underwent an OCT examination of their infarct-related artery before primary percutaneous coronary intervention. Results Of the 211 patients enrolled, 162 (76.7%) were men and ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) Bo Yu
    2. (3 articles) Harbin Medical University
    3. (1 articles) Yan Wang
    4. (1 articles) Haibo Jia
    5. (1 articles) University of Melbourne
    6. (1 articles) Dresden University of Technology
    7. (1 articles) University of Washington
    8. (1 articles) University of Bonn
    9. (1 articles) Ruikang K. Wang
    10. (1 articles) Julia Walther
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    12. (1 articles) Edmund Koch
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    Culprit plaque characteristics in women vs men with a first ST-segment elevation myocardial infarction: In vivo optical coherence tomography insights Impact of vessel curvature on neointimal healing after stent implantation as assessed by optical coherence tomography Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography Relationship between elevated plasma ceramides and plaque rupture in patients with ST-segment elevation myocardial infarction Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis Microvascular alterations in children with optic disk drusen evaluated by optical coherence tomography angiography Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis Donor specific anti-HLA antibodies and cardiac allograft vasculopathy: A prospective study using highly automated 3-D optical coherence tomography analysis