1. Articles from Mark I. van Berge Henegouwen

    1-2 of 2
    1. Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study

      Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study

      Treatment of resectable esophageal cancer includes neoadjuvant chemo-radiation therapy (nCRT) followed by esophagectomy in operable patients. High-risk surgery may have been avoided in patients with a pathological complete response (pCR). We investigated the feasibility of optical coherence tomography (OCT) to detect residual cancer and radiation-induced fibrosis in 10 esophageal cancer patients that underwent nCRT followed by esophagectomy. We compared our OCT findings with histopathology. Overall, OCT was able to differentiate between healthy tissue, fibrotic tissue, and residual cancer with a sensitivity and specificity of 79% and 67%, respectively. Hence, OCT has the potential to add to the assessment of a ...

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    2. Can we predict necrosis intra-operatively? Real-time optical quantitative perfusion imaging in surgery: study protocol for a prospective, observational, in vivo pilot study

      Can we predict necrosis intra-operatively? Real-time optical quantitative perfusion imaging in surgery: study protocol for a prospective, observational, in vivo pilot study

      Background Compromised perfusion as a result of surgical intervention causes a reduction of oxygen and nutrients in tissue and therefore decreased tissue vitality. Quantitative imaging of tissue perfusion during reconstructive surgery, therefore, may reduce the incidence of complications. Non-invasive optical techniques allow real-time tissue imaging, with high resolution and high contrast. The objectives of this study are, first, to assess the feasibility and accuracy of optical coherence tomography (OCT), sidestream darkfield microscopy (SDF), laser speckle contrast imaging (LSCI), and fluorescence imaging (FI) for quantitative perfusion imaging and, second, to identify/search for criteria that enable risk prediction of necrosis during ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Academic Medical Center at the University of Amsterdam
    2. (2 articles) Daniël M. de Bruin
    3. (2 articles) Ton G. van Leeuwen
    4. (2 articles) Boston University
    5. (2 articles) David A. Boas
    6. (1 articles) VU University Amsterdam
    7. (1 articles) Johannes F. de Boer
    8. (1 articles) Medical University of Vienna
    9. (1 articles) Korea University
    10. (1 articles) University of Ulsan
    11. (1 articles) University College London
    12. (1 articles) Baylor College of Medicine
    13. (1 articles) Semmelweis University
    14. (1 articles) Christoph K. Hitzenberger
    15. (1 articles) Pearse A. Keane
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    Can we predict necrosis intra-operatively? Real-time optical quantitative perfusion imaging in surgery: study protocol for a prospective, observational, in vivo pilot study Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study Comparative study between intravitreal ranibizumab and triamcinolone treatment of diabetic macular edema as regard to optical coherence tomography changes and visual acuity What’s New in Optical Coherence Tomography Angiography for Glaucoma (Book Chapter) Looking into the Future: Optical Coherence Tomography for the Assessment of Cardiac Allograft Vasculopathy Effects of Age on Peripapillary and Macular Vessel Density Determined Using Optical Coherence Tomography Angiography in Healthy Eyes Deep Neural Network Regression for Automated Retinal Layer Segmentation in Optical Coherence Tomography Images In-Stent Restenosis Lesion Morphology Related to Repeat Stenting Underexpansion as Evaluated by Optical Coherence Tomography Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography Angiography and optical coherence tomography assessment of the drug-coated balloon ESSENTIAL for the treatment of in-stent restenosis Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography Optical coherence tomography-guided dynamic focusing for combined optical and mechanical scanning multimodal photoacoustic microscopy