1. Articles from Colin E. Willoughby

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    1. Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography

      Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography

      Purpose : The purpose of this study was to compare optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) for the assessment of corneal neovascularization (CoNV). Methods : Patients with CoNV extending at least 3 mm into the cornea were included. All patients underwent corneal imaging at the same visit. Images were recorded using the AngioVue OCTA system (Optovue, Inc.) with the long corneal adaptor module (CAM-L). ICGA images were recorded with fluorescent filters using the Heidelberg system (HRA2 Scanning Laser Ophthalmoscope; Heidelberg Engineering). Images were graded for quality by two independent observers. Vessel parameters: area, number, diameter, branch and end ...

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    2. Deformation velocity imaging using optical coherence tomography and its applications to the cornea

      Deformation velocity imaging using optical coherence tomography and its applications to the cornea

      Optical coherence tomography (OCT) can monitor human donor corneas non-invasively during the de-swelling process following storage for corneal transplantation, but currently only resultant thickness as a function of time is extracted. To visualize and quantify the mechanism of de-swelling, we present a method exploiting the nanometer sensitivity of the Fourier phase in OCT data to image deformation velocities. The technique was demonstrated by non-invasively showing during de-swelling that osmotic flow through an intact epithelium is negligible and removing the endothelium approximately doubled the initial flow at that interface. The increased functional data further enabled the validation of a mathematical model ...

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      Mentions: Yalin Zheng
    1-2 of 2
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    1. (2 articles) Yalin Zheng
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