1. Articles from Joël Jovanovic

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    1. In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

      In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

      Spectral domain optical coherence tomography (SD-OCT) and scanning laser ophthalmoscopy (SLO) are extensively used in experimental ophthalmology. In the present protocol, mice expressing green fluorescent protein (gfp) under the promoter of Cx3cr1 (BALB/c-Cx3cr1 gfp/gfp ) were used to image microglia cells in vivo in the retina. Microglia are resident macrophages of the retina and have been implicated in several retinal diseases 1 , 2 , 3 , 4 , 5 , 6 . This protocol provides a detailed approach for generation of retinal B-scans, with SD-OCT, and imaging of microglia cell distribution in Cx3cr1 gfp/gfp mice with SLO in vivo, using an ophthalmic imaging ...

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    2. In Vivo Imaging of Cx3cr1 Reporter Mice with Spectral-domain Optical Coherence Tomography ...

      In Vivo Imaging of Cx3cr1 Reporter Mice with Spectral-domain Optical Coherence Tomography ...

      This protocol describes how high-resolution imaging techniques such as spectral domain optical coherence tomography and scanning laser ophthalmoscopy can be utilized in small rodents, using an ophthalmic imaging platform system, to obtain information on retinal thickness and microglial cell distribution, respectively.

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Bern University Hospital
    2. (2 articles) Martin S. Zinkernagel
    3. (1 articles) University of Bern
    4. (1 articles) Heidelberg Engineering
    5. (1 articles) Academic Medical Center at the University of Amsterdam
    6. (1 articles) Jichi Medical University
    7. (1 articles) University of Milan
    8. (1 articles) Bern University Hospital
    9. (1 articles) Capital Medical University
    10. (1 articles) Nanjing University of Science and Technology
    11. (1 articles) Martin S. Zinkernagel
    12. (1 articles) Junya Ako
    13. (1 articles) Frank D. Verbraak
    14. (1 articles) Giovanni Staurenghi
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