1. Articles from Julia N. S. d’Hooghe

    1-3 of 3
    1. Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma

      Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma

      Asthma is a chronic inflammatory disease characterized by airway remodeling (AR), including thickening of airway smooth muscle (ASM) as a key element of this alteration. 1 Patients with severe asthma may benefit from bronchial thermoplasty (BT), an endoscopic treatment that targets structural AR and induces ASM reduction. 2 Assessment of AR is critical to evaluate the impact of BT and might provide a tool for patient selection for BT. Polarization sensitive optical coherence tomography (PS-OCT) imaging has been proposed as a minimally invasive diagnostic method to assess ASM mass as an alternative to focal airway biopsies. Bronchoscopic standard optical coherence ...

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    2. 3D co-registration algorithm for catheter-based optical coherence tomography

      3D co-registration algorithm for catheter-based optical coherence tomography

      Applications of catheter-based optical coherence tomography (OCT) - originally developed for cardiovascular imaging - have expanded to other organ systems. However, currently available algorithms to co-register 3D OCT data to a second imaging modality were developed for cardiovascular applications and with it, are tailored to small tubular tissue structures. The available algorithms can often not be applied outside the cardiovascular system, e.g. when an OCT probe is introduced into the kidney, lungs, or wrist. Here, we develop a generic co-registration algorithm with potentially numerous applications. This algorithm only requires that the OCT probe is visible on the second imaging modality and ...

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    3. Optical coherence tomography for identification and quantification of human airway wall layers

      Optical coherence tomography for identification and quantification of human airway wall layers

      Background High-resolution computed tomography has limitations in the assessment of airway wall layers and related remodeling in obstructive lung diseases. Near infrared-based optical coherence tomography (OCT) is a novel imaging technique that combined with bronchoscopy generates highly detailed images of the airway wall. The aim of this study is to identify and quantify human airway wall layers both ex-vivo and in-vivo by OCT and correlate these to histology. Methods Patients with lung cancer, prior to lobectomy, underwent bronchoscopy including in-vivo OCT imaging. Ex-vivo OCT imaging was performed in the resected lung lobe after needle insertion for matching with histology. Airway ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Academic Medical Center at the University of Amsterdam
    2. (1 articles) National Institutes of Health
    3. (1 articles) VU University Amsterdam
    4. (1 articles) Abbott
    5. (1 articles) Sun Yat-Sen University
    6. (1 articles) Vanderbilt University
    7. (1 articles) Yale University
    8. (1 articles) Cleveland Clinic
    9. (1 articles) Northwestern University
    10. (1 articles) University of North Carolina
    11. (1 articles) Carl Zeiss Meditec
    12. (1 articles) Alcon
    13. (1 articles) Audioptics Medical
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