1. Articles from Annika W. M. Goorsenberg

    1-4 of 4
    1. In vivo multifunctional optical coherence tomography at the periphery of the lungs

      In vivo multifunctional optical coherence tomography at the periphery of the lungs

      Remodeling of tissue, such as airway smooth muscle (ASM) and extracellular matrix, is considered a key feature of airways disease. No clinically accepted diagnostic method is currently available to assess airway remodeling or the effect of treatment modalities such as bronchial thermoplasty in asthma, other than invasive airway biopsies. Optical coherence tomography (OCT) generates cross-sectional, near-histological images of airway segments and enables identification and quantification of airway wall layers based on light scattering properties only. In this study, we used a custom motorized OCT probe that combines standard and polarization sensitive OCT (PS-OCT) to visualize birefringent tissue in vivo in ...

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    2. Acute Airway Effects of Bronchial Thermoplasty Assessed by Optical Coherence Tomography (OCT)

      Acute Airway Effects of Bronchial Thermoplasty Assessed by Optical Coherence Tomography (OCT)

      Background: Bronchial Thermoplasty (BT) is an endoscopic treatment for severe asthma targeting airway smooth muscle (ASM) with thermal energy. The extent of treatment effect is largely unknown. Optical coherence tomography (OCT) is a high resolution imaging technique, using near-infrared light, that generates near-histology cross sectional images of the airway wall. Aim: Assess the extent of acute airway wall effects of BT with OCT and compare these to the untreated right middle lobe (RML). Methods: 15 severe asthma patients were treated with BT. During the third procedure, OCT imaging was performed in BT treated (sub)segmental airways in the upper lobes ...

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    3. Optical coherence tomography for identification and quantification of human airway wall layers

      Optical coherence tomography for identification and quantification of human airway wall layers

      Background High-resolution computed tomography has limitations in the assessment of airway wall layers and related remodeling in obstructive lung diseases. Near infrared-based optical coherence tomography (OCT) is a novel imaging technique that combined with bronchoscopy generates highly detailed images of the airway wall. The aim of this study is to identify and quantify human airway wall layers both ex-vivo and in-vivo by OCT and correlate these to histology. Methods Patients with lung cancer, prior to lobectomy, underwent bronchoscopy including in-vivo OCT imaging. Ex-vivo OCT imaging was performed in the resected lung lobe after needle insertion for matching with histology. Airway ...

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    1-4 of 4
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  2. Topics in the News

    1. (3 articles) Academic Medical Center at the University of Amsterdam
    2. (3 articles) Daniël M. de Bruin
    3. (1 articles) National Institutes of Health
    4. (1 articles) VU University Amsterdam
    5. (1 articles) University of Groningen
    6. (1 articles) Johannes F. de Boer
    7. (1 articles) Abbot
    8. (1 articles) Harvard University
    9. (1 articles) Massachusetts General Hospital
    10. (1 articles) University of North Carolina
    11. (1 articles) Baylor College of Medicine
    12. (1 articles) Masamichi Takano
    13. (1 articles) Joel S. Schuman
    14. (1 articles) Ik-Kyung Jang
    15. (1 articles) Yoshiyasu Minami
    16. (1 articles) Donald L. Budenz
    17. (1 articles) Gadi Wollstein
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    Optical coherence tomography for identification and quantification of human airway wall layers Acute Airway Effects of Bronchial Thermoplasty Assessed by Optical Coherence Tomography (OCT) In vivo multifunctional optical coherence tomography at the periphery of the lungs Optical Coherence Tomography Intensity Correlates with Extracellular Matrix Components in the Airway Wall High space-bandwidth in quantitative phase imaging using partially spatially coherent optical coherence microscopy and deep neural network Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes Early disability in ambulatory patients with multiple sclerosis: optical coherence tomography versus visual evoked potentials, a comparative study Dueling Deep Q-Network for Unsupervised Inter-frame Eye Movement Correction in Optical Coherence Tomography Volumes Atlas of Optical Coherence Tomography for Glaucoma (Textbook) In-vivo analysis of iron-gold composite nanoparticles as potential exogenous contrast agents for Magnetomotive Optical Coherence Tomography (MMOCT) Automatic Classification of Volumetric Optical Coherence Tomography Images via Recurrent Neural Network Noise-Powered Disentangled Representation for Unsupervised Speckle Reduction of Optical Coherence Tomography Images