1. Articles from Jose Sahel

    1-2 of 2
    1. In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography

      In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography

      Despite obvious improvements in visualization of the in vivo cornea through the faster imaging speeds and higher axial resolutions, cellular imaging stays unresolvable task for OCT, as en face viewing with a high lateral resolution is required. The latter is possible with FFOCT, a method that relies on a camera, moderate numerical aperture (NA) objectives and an incoherent light source to provide en face images with a micrometer-level resolution. Recently, we for the first time demonstrated the ability of FFOCT to capture images from the in vivo human cornea1. In the current paper we present an extensive study of appearance ...

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    2. Cell Motility as Contrast Agent in Retinal Explant Imaging With Full-Field Optical Coherence Tomography

      Cell Motility as Contrast Agent in Retinal Explant Imaging With Full-Field Optical Coherence Tomography

      Purpose : To use cell motility as a contrast agent in retinal explants. Methods : Macaque and mouse retinal explants were imaged with high resolution full field optical coherence tomography (FFOCT) and dynamic FFOCT, coupled with fluorescence imaging. Results : Static and dynamic FFOCT create complementary contrast from different structures within a cell. When imaging in vitro samples, static FFOCT detects steep refractive index gradients to reveal stationary structures including fibers, vessels, collagen, and cell contours, while dynamic FFOCT emphasizes metabolic activity of moving structures that are mainly intracellular, thus creating or enhancing contrast in cells that were previously hidden in noise. Dynamic ...

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    1-2 of 2
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    Cell Motility as Contrast Agent in Retinal Explant Imaging With Full-Field Optical Coherence Tomography In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography Special Section Guest Editorial: Advances in Retinal Imaging Optical coherence tomography angiography-derived flow density: a review of the influencing factors Changes in retinal and choriocapillaris density in diabetic patients receiving anti-vascular endothelial growth factor treatment using optical coherence tomography angiography Optical coherence tomography of patients with Parkinson’s disease and progressive supranuclear palsy Automatic quantification of superficial foveal avascular zone in optical coherence tomography angiography implemented with deep learning OCT-Based Periodontal Inspection Framework New World Resources and Perimeter Medical Imaging Provide Updates Regarding Their Amalgamation Transaction and Announce Amended and Restated Arrangement Agreement Retinal Vessel Density in Exudative and Non-Exudative Age-Related Macular Degeneration on Optical Coherence Tomography Angiography Use of Optical Coherence Tomography in a Patient with Erosive Oral Lichen Planus Treated with Low-Level Laser Therapy. Preliminary Findings Selective retinex enhancement based on the clustering algorithm and block-matching 3D for optical coherence tomography images