1. Articles from Royce W. S. Chen

    1-5 of 5
    1. OCT-Angiography and Ultra-Widefield Fluorescein Angiography for Early Detection of Adolescent Sickle Retinopathy

      OCT-Angiography and Ultra-Widefield Fluorescein Angiography for Early Detection of Adolescent Sickle Retinopathy

      Purpose Using standard screening techniques, sickle retinopathy reportedly occurs in 10% of adolescents with sickle cell disease (SCD). We performed a prospective, observational clinical study to determine if ultra-widefield fluorescein angiography (UWFA), spectral-domain optical coherence tomography (SD-OCT) and optical coherence tomography angiography (OCT-A) detect more frequent retinopathy in adolescents with SCD. Design Cross-sectional study. Methods Setting : Institutional. Subjects : Sixteen adolescents with SCD, ages 10-19 years, (mean age 14.9 years) and 5 age-equivalent controls (mean age 17.4 years). Observation Procedures: Examinations including acuity, standard slit-lamp biomicroscopy, UWFA, SD-OCT and OCT-A were performed. Main Outcome Measures : Sickle retinopathy defined by ...

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    2. Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia

      Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia

      Importance Evidence is mounting that achromatopsia is a progressive retinal degeneration, and treatments for this condition are on the horizon. Objectives To categorize achromatopsia into clinically identifiable stages using spectral-domain optical coherence tomography and to describe fundus autofluorescence imaging in this condition. Design, Setting, and Participants A prospective observational study was performed between 2010 and 2012 at the Edward S. Harkness Eye Institute, New York-Presbyterian Hospital. Participants included 17 patients (aged 10-62 years) with full-field electroretinography-confirmed achromatopsia. Main Outcomes and Measures Spectral-domain optical coherence tomography features and staging system, fundus autofluorescence and near-infrared reflectance features and their correlation to optical ...

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    3. Autofluorescence Imaging and Spectral-Domain Optical Coherence Tomography in Incomplete Congenital Stationary Night Blindness and Comparison With Retinitis Pigmentosa

      Autofluorescence Imaging and Spectral-Domain Optical Coherence Tomography in Incomplete Congenital Stationary Night Blindness and Comparison With Retinitis Pigmentosa
      Purpose: To test the hypothesis that the evaluation of retinal structure can have diagnostic value in differentiating between incomplete congenital stationary night blindness (CSNB2) and retinitis pigmentosa (RP). To compare retinal thickness differences between patients with CSNB2 and myopic controls. Design: Prospective cross-sectional study. Methods: Ten eyes of 5 patients diagnosed with CSNB2 (4 X-linked recessive, 1 autosomal recessive) and 6 eyes of 3 patients with RP (2 autosomal dominant, 1 autosomal recessive) were evaluated with spectral-domain optical coherence tomography (SD OCT) and fundus autofluorescence (FAF). Diagnoses of CSNB2 and RP were confirmed by full-field electroretinography (ERG). Manual segmentation of ...
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    4. Projection OCT fundus imaging for visualizing outer retinal pathology in non-exudative age related macular degeneration

      Aims: To demonstrate ultrahigh resolution, three-dimensional optical coherence tomography (3D-OCT) and projection OCT fundus imaging for enhanced visualization of outer retinal pathology in non-exudative age related macular degeneration (AMD). Methods: A high-speed, ultrahigh 3.5 µm resolution OCT prototype instrument was developed for the ophthalmic clinic. 83 patients with non-exudative AMD were imaged. Projection OCT fundus images were generated from 3D-OCT data by selectively summing different retinal depth levels. Results were compared with standard ophthalmic examination, including fundus photography and fluorescein angiography, when indicated. Results: Projection OCT fundus imaging enhanced the visualization of outer retinal pathology in non-exudative AMD. Different ...
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    5. High-Speed Ultrahigh-Resolution Optical Coherence Tomography Findings In Chronic Solar Retinopathy.

      High-speed ultrahigh-resolution optical coherence tomography images showed unprecedented detail of the outer retina in a patient with chronic solar retinopathy.Page: 103DOI: 10.1097/ICB.0b013e3181506993Authors: Chen, Royce W. S. BA *; Gorczynska, Iwona PhD *+; Srinivasan, Vivek J. MS +; Fujimoto, James G. PhD +; Duker, Jay S. MD *; Reichel, Elias MD *
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    1-5 of 5
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  2. Topics in the News

    1. (3 articles) Columbia University
    2. (2 articles) Tufts University
    3. (2 articles) Massachusetts Institute of Technology
    4. (2 articles) Vivek J. Srinivasan
    5. (2 articles) Elias Reichel
    6. (2 articles) Jay S. Duker
    7. (2 articles) James G. Fujimoto
    8. (2 articles) Iwona Gorczynska
    9. (1 articles) LuEsther T. Mertz Retinal Research Center
    10. (1 articles) Jerome Sherman
    11. (1 articles) University of Copenhagen
    12. (1 articles) University of Miami
    13. (1 articles) University of Ulsan
    14. (1 articles) Chinese Academy of Sciences
    15. (1 articles) Polytechnique Montreal
    16. (1 articles) Frédéric Lesage
    17. (1 articles) Young H. Yoon
    18. (1 articles) Jon Holmes
    19. (1 articles) Yoon Jeon Kim
    20. (1 articles) Michelson Diagnostics
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    Autofluorescence Imaging and Spectral-Domain Optical Coherence Tomography in Incomplete Congenital Stationary Night Blindness and Comparison With Retinitis Pigmentosa Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia OCT-Angiography and Ultra-Widefield Fluorescein Angiography for Early Detection of Adolescent Sickle Retinopathy The effect of software versions on the measurement of retinal vascular densities using optical coherence tomography angiography Peripapillary and Macular Microcirculation in Glaucoma Patients of African and European Descent Using Optical Coherence Tomography Angiography Comparison of two swept-source optical coherence tomography-based biometry devices Optical coherence tomography angiographic findings of lamellar macular hole: comparisons between tractional and degenerative subtypes Cerebral tissue pO2 response to treadmill exercise in awake mice Morphometric Optical Imaging of Microporated Nail Tissue: An Investigation of Intermethod Agreement, Reliability, and Technical Limitations Differences between Scheimpflug and optical coherence tomography in determining safety distances in eyes with an iris-fixating phakic intraocular lens Clinical efficacy of optical coherence tomography in sellar mass lesions: a meta-analysis In vivo characterization of extramammary Paget's disease by ultra‐high cellular resolution optical coherence tomography