1. Articles from Federico Sáenz-Francés

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    1. Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma

      Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma

      Objective: To evaluate the differences in peripapillary and macular vascular parameters by optical coherence tomography angiography (OCTA) between patients with primary congenital glaucoma (PCG) and healthy controls; and to determine their diagnostic accuracy. Material and methods: Observational, cross-sectional study including 39 eyes with PCG and 78 healthy eyes. Only one eye per patient was included. All included patients underwent a comprehensive ophthalmic examination and peripapillary and macular analysis were performed by Angioplex TM OCTA (Cirrus HD-OCT 5000) with a 4.5 × 4.5 mm optic nerve head scan and 6 × 6 mm macular scan. Global data and quadrant data from ...

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    2. Correlation Between Retrograde Trans-Synaptic Degeneration of Ganglion Cells and Optical Coherence Tomography Angiography Following Ischemic Stroke

      Correlation Between Retrograde Trans-Synaptic Degeneration of Ganglion Cells and Optical Coherence Tomography Angiography Following Ischemic Stroke

      Objective Following nerve injury, the projection of posterior visual pathway lesions into the macular ganglion cell layer (GCL) region indicates retrograde trans-synaptic degeneration (RTSD) as a mechanism of functional damage. Our purpose is to assess GCL damage and the impacts of ischemic brain lesions affecting the visual pathway on macular microvascularization in patients with stroke. Methods In a case-control study, we examined 15 ischemic stroke patients who showed visual field defects and 50 healthy controls using the high-resolution optical coherence tomography (OCT) techniques such as spectral domain-OCT (SD-OCT) to measure retinal nerve fiber layer (RNFL) and GCL thicknesses, and OCT ...

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    3. Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children

      Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children

      Aims : To evaluate the repeatability of the peripapillary and macular vascular parameters using optical coherence tomography angiography (OCT-A) in healthy children. Material and methods : Cross-sectional study including 34 eyes of 34 healthy children. After a complete medical examination, two consecutive OCT-A exams were done using AngioPlex Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA, USA) in the same session. The scan area used was 6x6 mm for the analysis of the superficial vascular plexus (SVP) in the macula, and 4.5x4.5 mm for the peripapillary plexus. To study the repeatability of the measurements, the intraclass correlation coefficient (ICC) and the ...

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    4. Analysis of inner and outer retinal layers using spectral domain optical coherence tomography ...

      Analysis of inner and outer retinal layers using spectral domain optical coherence tomography ...

      Objective To analyse the morphological features and diagnostic ability of eight macular retinal layers using a new segmentation software Heidelberg's Spectralis Optical Coherence Tomography (SD-OCT) in healthy, ocular hypertensive and primary open angle glaucoma patients. Methods Single-center, cross-sectional, non-interventional study. 193 eyes from 193 consecutive patients (56 controls, 63 ocular hypertensives, 32 early primary open glaucoma patients and 42 moderate-advanced primary open glaucoma patients). Those patients presenting any retinal disease were excluded. Macular segmentation of the retinal layers was automatically performed using the new segmentation Heidelberg's Spectralis OCT software providing measurements for eight retinal layers. The software provides ...

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    5. Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Purpose To compare the diagnostic performance of circumpapillary retinal nerve fiber layer (cpRNFL) analysis versus segmented ganglion cell complex analysis both by spectral-domain optical coherence tomography (SD-OCT) in children with primary congenital glaucoma (PCG). Methods Participants were 40 children diagnosed with PCG and 60 healthy children. Ophthalmological data collected (for one eye per child) were cup-disc ratio (C/D) and axial length (AL). SD-OCT with automated segmentation was used to measure the thicknesses and volumes of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL). For the cpRNFL measurements conventional S-D OCT software ...

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    6. Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Objective To examine differences in individual retinal layer thicknesses measured by spectral domain optical coherence tomography (SD-OCT) (Spectralis ® ) produced with age and according to sex. Design Cross-sectional, observational study. Methods The study was conducted in 297 eyes of 297 healthy subjects aged 18 to 87 years. In one randomly selected eye of each participant the volume and mean thicknesses of the different macular layers were measured by SD-OCT using the instrument's macular segmentation software. Main outcome measures Volume and mean thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer ...

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    7. Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Article Authors Metrics Comments Related Content Abstract Introduction Methods Results Discussion Supporting information Acknowledgments References Reader Comments (0) Media Coverage Figures Abstract Purpose Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). Methods On this transversal, observational study, 300 patients between 18 to 87 years old and without an ophthalmological condition were recruited. Macular OCT scans were performed on all patients (Spectralis OCT, Heidelberg Engineering). An axial length measurement, and keratometry were performed using an ...

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    1-7 of 7
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    Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma Analysis of inner and outer retinal layers using spectral domain optical coherence tomography ... Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children Correlation Between Retrograde Trans-Synaptic Degeneration of Ganglion Cells and Optical Coherence Tomography Angiography Following Ischemic Stroke Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma Comparison of Anterior Segment Measurements with a New Multifunctional Unit and Five Other Devices Efficacy of Notal Vision Home OCT demonstrated by a series of scientific and clinical work Synergy Between morpHOlogical and inflammatoRy Evaluation in Predicting Long-term Coronary Plaque Progression Altered ocular microvasculature in patients with systemic sclerosis and very early disease of systemic sclerosis using optical coherence tomography angiography Assessment of macular findings by OCT angiography in patients without clinical signs of diabetic retinopathy: radiomics features for early screening of diabetic retinopathy