1. Articles from Reza Mirshahi

    1-9 of 9
    1. Differentiating features of OCT angiography in diabetic macular edema

      Differentiating features of OCT angiography in diabetic macular edema

      The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in ...

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    2. Foveal avascular zone segmentation in optical coherence tomography angiography images using a deep learning approach

      Foveal avascular zone segmentation in optical coherence tomography angiography images using a deep learning approach

      The purpose of this study was to introduce a new deep learning (DL) model for segmentation of the fovea avascular zone (FAZ) in en face optical coherence tomography angiography (OCTA) and compare the results with those of the device’s built-in software and manual measurements in healthy subjects and diabetic patients. In this retrospective study, FAZ borders were delineated in the inner retinal slab of 3 × 3 enface OCTA images of 131 eyes of 88 diabetic patients and 32 eyes of 18 healthy subjects. To train a deep convolutional neural network (CNN) model, 126 enface OCTA images (104 eyes with ...

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    3. Comparison of Superficial and Deep Foveal Avascular Zone Area in Healthy Subjects Using Two Spectral Domain Optical Coherence Tomography Angiography Devices

      Comparison of Superficial and Deep Foveal Avascular Zone Area in Healthy Subjects Using Two Spectral Domain Optical Coherence Tomography Angiography Devices

      Purpose: To compare the area of the foveal avascular zone (FAZ) in the superficial and deep retinal layers using two different spectral-domain optical coherence tomography angiography (OCTA) devices. Methods: A cross-sectional comparative study was conducted to obtain macular OCTA images from healthy subjects using Optovue RTVue XR Avanti (Optovue, Inc, Fremont, CA) and Spectralis HRA+OCTA (Heidelberg Engineering, Heidelberg, Germany). Two independent trained graders measured the FAZ area using automated slab segmentation. The FAZ area in the superficial and deep retinal layers were compared. Results: Twenty-three eyes of 23 subjects were included. The graders agreement was excellent (>0.86) for ...

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    4. Stepwise segmentation error correction in optical coherence tomography angiography images of patients with diabetic macular edema

      Stepwise segmentation error correction in optical coherence tomography angiography images of patients with diabetic macular edema

      Aim: To determine the minimum number of optical coherence tomography B-scan corrections required to provide acceptable vessel density measurements on optical coherence tomography angiography images in eyes with diabetic macular edema. Methods: In this prospective, noninterventional case series, the optical coherence tomography angiography images of eyes with center-involving diabetic macular edema were assessed. Optical coherence tomography angiography imaging was performed using RTVue Avanti spectral-domain optical coherence tomography system with the AngioVue software (V.2017.1.0.151; Optovue, Fremont, CA, USA). Segmentation error was recorded and manually corrected in the inner retinal layers in the central foveal, 100th and 200th ...

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      Mentions: Visionix
    5. Effect of panretinal photocoagulation on macular vasculature using optical coherence tomography angiography

      Effect of panretinal photocoagulation on macular vasculature using optical coherence tomography angiography

      Background: To evaluate the changes of macular vascular density in the superficial capillary (SCP) and the deep capillary plexus (DCP), foveal avascular area (FAZ), choroidal flow, and macular thickness after pan-retinal photocoagulation (PRP). Methods: In this prospective interventional non-comparative case series, patients with very severe nonproliferative (NPDR) and early proliferative diabetic retinopathy (PDR) and no significant macular edema who were candidates for pan-retinal photocoagulation underwent measurement of corrected distance visual acuity (CDVA), optical coherence tomography (OCT), Optical coherence tomography angiography (OCTA) at the baseline, 1, and 6 months following completion of PRP treatment. Results: Thirty-nine eyes from 21 patients with ...

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      Mentions: UC Irvine
    6. Optical coherence tomography angiography (OCTA) applications in ocular oncology

      Optical coherence tomography angiography (OCTA) applications in ocular oncology

      Optical coherence tomography angiography (OCTA) is a revolutionary method in the visualization of the vascular system in different retinal and choroidal layers. During the last 4 years since the commercial availability of different OCTA devices, attempts have been made to utilize this technology in various aspects of ocular oncology from the differentiation of benign and malignant lesions to assisting in evaluation of post-treatment complications, such as radiation retinopathy. However, current OCTA technology is restricted by various artefacts and inherent limitations, some of which are more pronounced in the presence of elevated tumoural lesions. Imminent advancements in OCTA systems and image ...

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    7. Optical coherence tomography angiography in choroidal melanoma and nevus

      Optical coherence tomography angiography in choroidal melanoma and nevus

      Synopsis: In optical coherence tomography angiography, the choroidal vascular flow rate in choroidal melanoma is significantly lower than that in choroidal nevus. Objective: The objective of this study was to describe the choriocapillaris and retinal features imaged by optical coherence tomography angiography (OCTA) in eyes with choroidal nevus from small malignant choroidal melanoma. Methods: In this retrospective, noninvasive, observational study, 11 patients diagnosed with small choroidal mass (five with choroidal nevus and six with malignant melanoma) who underwent dilated fundus examination, ocular ultrasonography and OCTA images were compared. Results: In choroidal nevus of all patients, OCTA demonstrated a hyporeflective mass ...

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    8. The Quantitative Measurements of Vascular Density and Flow Area of Optic Nerve Head Using Optical Coherence Tomography Angiography

      The Quantitative Measurements of Vascular Density and Flow Area of Optic Nerve Head Using Optical Coherence Tomography Angiography

      Purpose: The purpose of this study was to evaluate the vascular density (VD) and the flow area on optic nerve head (ONH) and peripapillary area, and the impact of age and sex using optical coherence tomography angiography (OCTA) in healthy human subjects. Methods: Both eyes of each volunteer were scanned by an RTVue XR Avanti; Optovue with OCTA using the split-spectrum amplitude-decorrelation angiography algorithm technique. Masked graders evaluated enface angiodisc OCTA data. The flow area of ONH and the VD were automatically calculated. Results: A total of 79 eyes of patients with a mean age of 37.03+/-11.27 ...

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      Mentions: Visionix
    9. The Quantitative Measurements of Vascular Density and Flow Areas of Macula Using Optical Coherence Tomography Angiography in Normal Volunteers

      The Quantitative Measurements of Vascular Density and Flow Areas of Macula Using Optical Coherence Tomography Angiography in Normal Volunteers

      BACKGROUND AND OBJECTIVE: The quantification of the density of macular vascular networks and blood flow areas in the foveal and parafoveal area in healthy subjects using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Cross-sectional, prospective study in an institutional setting at the Retina Services of Farabi Eye Hospital. One hundred twelve normal volunteers with no known ocular or systemic disease were included, including patient numbers (one or both eyes), selection procedures, inclusion/exclusion criteria, randomization procedure, and masking. En face angiogram OCTA was performed on a 3 mm × 3 mm region centered on the macula. Automated thresholding and measuring ...

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    1-9 of 9
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    The Quantitative Measurements of Vascular Density and Flow Areas of Macula Using Optical Coherence Tomography Angiography in Normal Volunteers The Quantitative Measurements of Vascular Density and Flow Area of Optic Nerve Head Using Optical Coherence Tomography Angiography Optical coherence tomography angiography in choroidal melanoma and nevus Optical coherence tomography angiography (OCTA) applications in ocular oncology Effect of panretinal photocoagulation on macular vasculature using optical coherence tomography angiography Stepwise segmentation error correction in optical coherence tomography angiography images of patients with diabetic macular edema Comparison of Superficial and Deep Foveal Avascular Zone Area in Healthy Subjects Using Two Spectral Domain Optical Coherence Tomography Angiography Devices Foveal avascular zone segmentation in optical coherence tomography angiography images using a deep learning approach Differentiating features of OCT angiography in diabetic macular edema New insights from non-invasive imaging: from prospection of skin photodamages to training with mobile application Short-sighted woman assumes debilitating headaches mean she needs new glasses but discovers she has multiple sclerosis Shedding light on the impact of microplastics on lentil seedling growth