1. Articles from Carsten H. Meyer

    1-14 of 14
    1. Resistive index of ophthalmic artery correlates with retinal pigment epithelial alterations on spectral domain optical coherence tomography in diabetic retinopathy

      Resistive index of ophthalmic artery correlates with retinal pigment epithelial alterations on spectral domain optical coherence tomography in diabetic retinopathy

      Background Retinal pigment epithelium (RPE) plays a significant role in maintenance of integrity of retinal photoreceptors and choriocapillaries. RPE derives its blood supply through ophthalmic artery (OA) via choriocapillaries. RPE topographic alterations have been observed to be associated with severity of retinopathy. The present study was undertaken to assess the correlation between resistive index (RI) of the OA with RPE topographic alterations on Spectral-Domain optical coherence tomography (SD-OCT), to our knowledge, it is for the first time. Methods A tertiary care center based cross-sectional study was undertaken after informed consent. Sample size was calculated using 95% confidence interval. Seventy five ...

      Read Full Article
      Mentions: Sandeep Saxena
    2. Spectral Domain Optical Coherence Tomography in Macular Disease (Textbook)

      Spectral Domain Optical Coherence Tomography in Macular Disease (Textbook)

      . This book aims to build concepts and create a solid foundation in the field of optical coherence tomography (OCT) for the general ophthalmologists as well as for the resident trainees and fellows. The chapters are written by leading international authorities in a style comprehensible to a broad audience. Numerous clinical pictures and SD-OCT scans help elucidate various clinical entities.OCT is the optical analog of ultrasound imaging and has emerged as a powerful imaging technique that enables non-invasive, in-vivo, high-resolution, cross-sectional imaging in retinal tissue. A new generation spectral domain optical coherence tomography (SD-OCT) technology has now been developed, representing ...

      Read Full Article
    3. The potential of spectral domain optical coherence tomography imaging based retinal biomarkers

      The potential of spectral domain optical coherence tomography imaging based retinal biomarkers

      Background Biomarker”, a merged word of “biological marker”, refers to a broad subcategory of medical signs that objectively indicate the state of health, and well-being of an individual. Biomarkers hold great promise for personalized medicine as information gained from diagnostic or progression markers can be used to tailor treatment to the individual for highly effective intervention in the disease process. Optical coherence tomography (OCT) has proved useful in identifying various biomarkers in ocular and systemic diseases. Main body Spectral domain optical coherence tomography imaging-based biomarkers provide a valuable tool for detecting the earlier stages of the disease, tracking progression, and ...

      Read Full Article
      Mentions: Sandeep Saxena
    4. Spectral Domain Optical Coherence Tomography in Macular Diseases (Textbook)

      Spectral Domain Optical Coherence Tomography in Macular Diseases (Textbook)

      Undoubtedly, optical coherence tomography has changed the approach of clinicians in their daily practice. The evolution of technology from time domain to spectral domain and swept source OCT increased the possibilities of imaging the retinal and choroidal details. Newer evaluations are now available to better understand the diseases and to fi nd new biomarkers for retinal and choroidal pathologies. From measurement to morphology could be the right description of changes occurring from time domain to spectral domain. The possibility to visualize retinal and choroidal morphology in real life and not only post-mortem allowed a better understanding not only of the ...

      Read Full Article
    5. Three-dimensional spectral domain optical coherence tomography in vitreomacular traction

      Three-dimensional spectral domain optical coherence tomography in vitreomacular traction

      Spectral domain optical coherence tomography (SD-OCT) is a non-invasive tool providing unprecedented imaging and analysis of vitreomacular interface. Two cases of vitreomacular traction were analysed by advanced three–dimensional (3D) SD-OCT imaging. En-face OCT permitted localisation of the exact point of attachment of vitreous to retina. A comprehensive view of the surface topography and anatomical configuration of vitreomacular affection was revealed by 3D imaging with segmentation technique. Macular change analysis programme revealed progression to full-thickness macular hole in the second case. Non-invasive high-resolution SD-OCT imaging has transformed the understanding and management of vitreomacular traction. Its role is further reinforced by ...

      Read Full Article
      Mentions: Sandeep Saxena
    6. Three-dimensional spectral domain optical coherence tomography in chronic exposure to welding arc

      Three-dimensional spectral domain optical coherence tomography in chronic exposure to welding arc

      Three-dimensional spectral domain optical coherence tomography was performed in a 26-year-old man with chronic exposure to welding arc. Advanced macular visualisation provided significant findings of inner segment-ellipsoid zone disruption with the presence of cystoid changes and hyper-reflective material in the area of disruption. The external limiting membrane was intact in both the eyes. C-scan retinal pigment epithelium fit map of the left eye revealed a well-delineated defect whereas the right eye showed a poorly delineated smaller defect. The hyper-reflective material can be hypothesised to originate from the disrupted photoreceptor layer. The hyper-reflective material was more evident in the left eye ...

      Read Full Article
      Mentions: Sandeep Saxena
    7. Three-dimensional spectral domain optical coherence tomography in X linked foveal retinoschisis

      Three-dimensional spectral domain optical coherence tomography in X linked foveal retinoschisis
      Spectral domain optical coherence tomography (SD-OCT) was performed in two cases of bilateral X linked foveal retinoschisis of different age groups. On fundus examination spoke wheel and honeycomb pattern of cysts were observed along with retinal nerve fibre layer (RNFL) defects. On SD-OCT, schisis was observed in the outer plexiform layer. External limiting membrane disruption was observed in the subfoveal area, along with disruption of outer nuclear layer (ONL) and inner–outer segment junction. Elevation of ONL due to tractional pull of central palisade was a novel observation. Retinoschisis extended beyond the optic disc up to the nasal region. Extracted ...
      Read Full Article
      Mentions: Sandeep Saxena
    8. Three-dimensional spectral domain optical coherence tomography of retina in choroidal metastasis due to uterine endometrial carcinoma

      Three-dimensional spectral domain optical coherence tomography of retina in choroidal metastasis due to uterine endometrial carcinoma

      Spectral domain optical coherence tomography (SD-OCT) three-dimensional (3D) imaging in choroidal metastasis, due to uterine endometrial carcinoma, is reported for the first time. SD-OCT revealed a dome-shaped elevation of the retina. Neurosensory detachment with splitting of the retinal layers, at some places, was observed. 3D SD-OCT allows evaluation of secondary retinal pigment epithelial and intraretinal changes due to metastatic choroidal lesion

      Read Full Article
    9. Simultaneous Confocal Scanning Laser Ophthalmoscopy Combined with High-Resolution Spectral-Domain Optical Coherence Tomography: A Review

      Simultaneous Confocal Scanning Laser Ophthalmoscopy Combined with High-Resolution Spectral-Domain Optical Coherence Tomography: A Review
      We aimed to evaluate technical aspects and the clinical relevance of a simultaneous confocal scanning laser ophthalmoscope and a high-speed, high-resolution, spectral-domain optical coherence tomography (SDOCT) device for retinal imaging. The principle of confocal scanning laser imaging provides a high resolution of retinal and choroidal vasculature with low light exposure. Enhanced contrast, details, and image sharpness are generated using confocality. The real-time SDOCT provides a new level of accuracy for assessment of the angiographic and morphological correlation. The combined system allows for simultaneous recordings of topographic and tomographic images with accurate correlation between them. Also it can provide simultaneous multimodal ...
      Read Full Article
    10. Spectral-domain optical coherence tomography in healed ocular toxoplasmosis

      Spectral-domain optical coherence tomography in healed ocular toxoplasmosis
      Toxoplasmosis is the most common cause of infectious retinitis in immunocompetent individuals. The seroprevalence of Toxoplasma gondii is different throughout the world. Among this positive population, only 1% has meaningful chorioretinitis scars. Ocular toxoplasmosis is sometimes a benign and self-limiting disease. It can also cause central or total visual loss. Legal blindness occurs in nearly one quarter of the affected eyes. It is caused either directly by involvement of the macula or optic nerve or indirectly by complications secondary to inflammation [1, 2]. Spectral-domain optical coherence tomography (SD-OCT) in active toxoplasmosis enabled identification of morphological features underestimated on clinical examination ...
      Read Full Article
    11. Optical Coherence Tomography-Measured Pigment Epithelial Detachment Height As A Predictor for Retinal Pigment Epithelial Tears Associated With Intravitreal Bevacizumab Injections

      Purpose: The purpose was to study preinjection optical coherence tomography-related factors in age-related macular degeneration eyes with retinal pigment epithelial detachment (PED) that may predispose retinal pigment epithelial (RPE) tears associated with intravitreal bevacizumab injections. Methods: This multicenter retrospective case series involving 9 retina specialists and 7 centers investigated Stratus optical coherence tomography parameters in eyes with vascularized PED (vPED) from February 2006 to February 2007. Of the 1,280 eyes in 1,255 patients receiving 2,890 intravitreal injections, there were 125 eyes with vPED. For every vPED eye that developed an RPE tear (Group 1), 3 or more ...
      Read Full Article
    12. Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high-resolution, spectral-domain optical coherence tomography

      Purpose: To evaluate the clinical relevance of a new diagnostic modality, simultaneous confocal scanning laser ophthalmoscopy (cSLO) and high-speed, high-resolution, spectral-domain optical coherence tomography (OCT), for the visualization of macular pathologies. Methods: OCT images and simultaneous recording of fluorescein angiography, indocyanine green (ICG) angiography, infrared, and blue reflectance ('red-free') or fundus autofluorecence (FAF) images were obtained with a novel imaging device (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany). An optically pumped solid-state laser generated the excitation wavelength (488 nm) required for blue reflectance, FAF and fluorescein angiography images. For ICG angiography and infrared imaging, diode laser sources at 790 and ...
      Read Full Article
    13. Scleral Incisions Evaluated By with Anterior Segment Optical Coherence Tomography

      The article by Taban and associates investigated the wound morphology in 23-gauge sutureless oblique sclerotomies for cannula microincision 3-port pars plana vitrectomies with the Visante anterior segment optical coherence tomography (OCT). The sclera was penetrated with a 23-gauge trocar cannula microvitrectomy system as tangentially as possible parallel to the limbus. Once the outer half was penetrated, the angle of the trocar was changed to 90 degrees to insert into the globe. All incisions were imaged in 14 patients with the Visante OCT device with an axial resolution of 18 μm and transverse resolution of 60 μm. The gross clinical examination ...
      Read Full Article
    14. Clinical use and research applications of Heidelberg retinal angiography and spectral-domain optical coherence tomography - a review

      Fluorescein angiography (FA) was discovered by Nowotny and Alvis in the 1960s of the 20th century and has evolved to become the 'Gold standard' for macular diagnostics. Scanning laser imaging technology achieved enhancement of contrast and resolution. The combined Heidelberg retina angiograph (HRA2) adds novel innovative features to established fundus cameras. The principle of confocal scanning laser imaging provides a high resolution of retinal and choroidal vasculature with low light exposure providing comfort and safety for the patient. Enhanced contrast, details and image sharpness image are generated using confocality. For the visualization of the choroid an indocyanine green angiography (ICGA ...
      Read Full Article
    1-14 of 14
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (9 articles) Sandeep Saxena
    2. (3 articles) University of Bonn
    3. (3 articles) Heidelberg Engineering
    4. (2 articles) UCLA
    5. (2 articles) Srinivas R. Sadda
    6. (1 articles) Frank G. Holz
    7. (1 articles) Hendrik P. N. Scholl
    8. (1 articles) Peter Charbel Issa
    9. (1 articles) Steffen Schmitz-Valckenberg
    10. (1 articles) Carl Zeiss Meditec
    11. (1 articles) Tufts University
    12. (1 articles) UCLA
    13. (1 articles) Massachusetts General Hospital
    14. (1 articles) Capital Medical University
    15. (1 articles) University of Auckland
    16. (1 articles) Frederique Vanholsbeeck
    17. (1 articles) Francesco Bandello
    18. (1 articles) Yoshiyasu Minami
    19. (1 articles) Hang Lee
    20. (1 articles) Carl Zeiss Meditec
  3. Popular Articles

  4. Picture Gallery

    Spectral-domain optical coherence tomography in healed ocular toxoplasmosis Simultaneous Confocal Scanning Laser Ophthalmoscopy Combined with High-Resolution Spectral-Domain Optical Coherence Tomography: A Review Three-dimensional spectral domain optical coherence tomography of retina in choroidal metastasis due to uterine endometrial carcinoma Three-dimensional spectral domain optical coherence tomography in X linked foveal retinoschisis Three-dimensional spectral domain optical coherence tomography in vitreomacular traction Spectral Domain Optical Coherence Tomography in Macular Disease (Textbook) Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study Macular neovascularization in AMD, CSC and best vitelliform macular dystrophy: quantitative OCTA detects distinct clinical entities Effects of the Gaze Fixation Position on AS-OCT Measurements of the Limbus and Extraocular Muscle Insertion Site Distance Anterior Segment Optical Coherence Tomography in Locating the Insertion of Horizontal Extraocular Muscles After Strabismus Surgery Optical coherence tomography-guided management of underexpanded stent in calcified coronary lesion OCT-angiography for diagnosis and response to treatment of subretinal neovascularization secondary to idiopathic macular telangiectasia type 2