1. Articles from Alexander Lam

    1-3 of 3
    1. Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study

      Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study

      Aims To evaluate the distributions of quantitative optical coherence tomography angiography (OCT-A) metrics and its associated factors in children. Methods 1059 children aged 6–8 years were recruited from the Hong Kong Children Eye Study. All the participants underwent OCT-A with a swept-source OCT. Retinal microvasculature on superficial capillary plexus was assessed and quantified by a customised automated image analysis programme. Univariable and multiple linear regression analyses were performed to determine systemic (body mass index (BMI), waist circumference, head circumference and blood pressure), demographic and ocular (axial length (AL), macular thickness and volume, retinal nerve fibre layer (RNFL) thickness and ...

      Read Full Article
    2. Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study

      Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study

      Aim To examine the correlation of best-corrected visual acuity (BCVA) with intercapillary area (ICA) measured from optical coherence tomography angiography (OCT-A) in patients with diabetes, and to compare the strength of associations between BCVA with ICA and other OCT-A metrics. Methods A cross-sectional study involved 447 eyes from 299 patients with diabetes. All participants underwent OCT-A with a swept-source OCT (Triton DRI-OCT, Topcon, Tokyo, Japan). An automated customised MATLAB programme was used to quantify ICA (the mean of the 10 largest areas including foveal avascular zone (FAZ) area (ICA10_FAZ) and excluding FAZ area (ICA10_excFAZ)) and other OCT-A metrics (FAZ area ...

      Read Full Article
    3. Determinants of Quantitative Optical Coherence Tomography Angiography Metrics in Patients with Diabetes

      Determinants of Quantitative Optical Coherence Tomography Angiography Metrics in Patients with Diabetes

      Early microvascular damage in diabetes (e.g. capillary nonperfusion and ischemia) can now be assessed and quantified with optical coherence tomography-angiography (OCT-A). The morphology of vascular tissue is indeed affected by different factors; however, there is a paucity of data examining whether OCT-A metrics are influenced by ocular, systemic and demographic variables in subjects with diabetes. We conducted an observational cross-sectional study and included 434 eyes from 286 patients with diabetes. Foveal avascular zone (FAZ) area, FAZ circularity, total and parafoveal vessel density (VD), fractal dimension (FD), and vessel diameter index (VDI) from the superficial capillary plexus OCT-angiogram were measured ...

      Read Full Article
    1-3 of 3
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) The Chinese University of Hong Kong
    2. (1 articles) Singapore Eye Research Institute
    3. (1 articles) Tien Yin Wong
  3. Popular Articles

  4. Picture Gallery

    Determinants of Quantitative Optical Coherence Tomography Angiography Metrics in Patients with Diabetes Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study Image contrast correction method in full-field optical coherence tomography Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography Optical coherence tomography angiography characteristics of acute retinal arterial occlusion Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT) Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data Optical coherence tomography-based patient-specific coronary artery reconstruction and fluid–structure interaction simulation