1. Articles from Peng Chen

    1-2 of 2
    1. Velocity range estimation for liquid flow based on optical micro-angiography

      Velocity range estimation for liquid flow based on optical micro-angiography

      Optical micro-angiography (OMAG) is widely used in vivo imaging due to its non-invasive and highly sensitive measurements. It can effectively distinguish flowing and stationary particles for applications such as micro-size blood vessel. However, the detectable flow velocity of OMAG is restricted by the system parameters. Their relationship is usually unknown and thus increase the difficulty of OMAG application on liquid flow measurements. This study for the first time proposes a velocity range estimation formula to quantify the measurable velocity range of liquid flow for the OMAG and the ultrahigh-sensitivity OMAG (UHS-OMAG) methods. The velocity range not only provides rough velocity ...

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    2. Iron-oxide nanoparticles powered micro optical coherence tomography for in situ imaging the penetration and swelling of polymeric microneedles in skin

      Iron-oxide nanoparticles powered micro optical coherence tomography for in situ imaging the penetration and swelling of polymeric microneedles in skin

      In recent years, polymeric microneedles (MNs) have attracted keen interests among researchers for their applicability in transdermal drug delivery and interstitial skin fluid (ISF) extraction. When design and characterize such devices, it is critical to monitor their real-time in vitro and in vivo performances to optimize the desired effects, yet most of the existing methods are incapable of such functions. To address this unmet need, we develop a real-time non-invasive imaging methodology by integrating iron oxide (Fe3O4) nanoparticles into polymeric MNs to enhance image contrast for micro-optical coherence tomography (µOCT) imaging. Using the Fe3O4 integrated polystyrene-block-poly (acrylic acid) (PS-b-PAA) MNs ...

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      Mentions: Linbo Liu
    1-2 of 2
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  2. Topics in the News

    1. (1 articles) Tsinghua University
    2. (1 articles) Zhejiang University
    3. (1 articles) Linbo Liu
    4. (1 articles) Yonghong He
    5. (1 articles) Duke University
    6. (1 articles) Sina Farsiu
    7. (1 articles) PhotoniCare
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