1. Articles from Janusz Michalewski

    1-18 of 18
    1. Swept Source optical coherence tomography of choroidal nevi

      Swept Source optical coherence tomography of choroidal nevi

      Objective The aim of this article is to report on retinal and choroidal morphology in choroidal nevi documented with Swept Source optical coherence tomography (SS-OCT). Design This is a retrospective, observational study. Participants We included 27 consecutive patients with choroidal nevi. Mean age was 66.3 years (21–95 years). Methods The SS-OCT scanning protocol consisted of a single line scan through the centre of the nevi with a resolution of 3 µm, built from 1024 A-scans, with a length of 12 mm. We attempted to visualize the outer choroidoscleral boundary and suprachoroidal layer (SCL) below the choroidal nevus and ...

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    2. Swept-Source optical coherence tomography correlations between retina and choroid before and after vitrectomy for epiretinal membranes

      Swept-Source optical coherence tomography correlations between retina and choroid before and after vitrectomy for epiretinal membranes

      Purpose To describe retinal and choroidal morphology before and after surgery for epiretinal membranes (ERM) in Swept Source OCT (SS-OCT). Additionally, to evaluate factors responsible for visibility of the suprachoroidal layer (SCL) and suprachoroidal space (SCS). Design Prospective consecutive case series. Material and Methods 29 eyes of 29 patients with symptomatic, idiopathic ERM were included. Pars plana vitrectomy with ERM removal and ILM peeling was performed. We examined patients with SS-OCT twice preoperatively (9-12 months and one week before surgery), then postoperatively at 1 week, 6 and 12 months. Results Twelve months after surgery visual acuity improved to 20/50 ...

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    3. The outer choroidoscleral boundary in full-thickness macular holes before and after surgery—a swept-source OCT stud

      The outer choroidoscleral boundary in full-thickness macular holes before and after surgery—a swept-source OCT stud

      Purpose To report on choroidal thickness and the morphology of the outer choroidoscleral boundary in swept-source OCT in patients with full-thickness macular holes (FTMH) before and after surgery. Methods Single center matched case–control study of 32 patients with FTMH (group 1), fellow eyes (group 2), and 32 eyes of 32 healthy controls (group 3). All eyes from group 1 had vitrectomy with a minimum follow-up of 3 months. Main outcome measures were the visibility and regularity of the outer choroidoscleral boundary (CSB), and additionally the eventual visibility of the suprachoroidal layer (SCL). Results Choroidal thickness was indifferent between groups ...

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    4. CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES

      CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES

      Purpose: In eyes with epiretinal membranes (ERMs), retinal arteries become dilated and tortuous. This may correlate with the hemodynamics of the affected areas and possibly with choroidal thickness. The aim of this study was to estimate choroidal thickness before and after vitrectomy for idiopathic ERM in the operated eye and in the unaffected fellow eye. Methods: A prospective study of 21 patients with idiopathic ERMs. We obtained swept source optical coherence tomography images that simultaneously evaluated the vitreous, retina, and choroid. We performed choroidal thickness measurements before pars plana vitrectomy with ERM removal and internal limiting membrane peeling. We took ...

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    5. Spectral-domain optical coherence tomography features preceding new-onset neovascular membrane formation

      Spectral-domain optical coherence tomography features preceding new-onset neovascular membrane formation

      Objective To determine the frequency and characteristic spectral-domain optical coherence tomography (SD-OCT) features preceding new-onset choroidal neovascularization (CNV) in the fellow eye of neovascular age-related macular degeneration (AMD) with SD-OCT. Design A prospective, observational study. Participants Sixty-eight fellow eyes of patients with unilateral CNV. Methods SD-OCT was performed at baseline and then monthly. The main outcome measure is the description of retinal morphology 1 month before new onset of neovascularization. Results During the 48-month observation period, new-onset CNV was observed in 27 fellow eyes. Several morphologic features characterized SD-OCT images ≥1 months before new onset of CNV. These included new ...

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    6. SUPRACHOROIDAL LAYER AND SUPRACHOROIDAL SPACE DELINEATING THE OUTER MARGIN OF THE CHOROID IN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      SUPRACHOROIDAL LAYER AND SUPRACHOROIDAL SPACE DELINEATING THE OUTER MARGIN OF THE CHOROID IN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To define the morphology of outer choroidal margins in swept-source optical coherence tomography. Methods: This is a prospective observational study of 180 eyes: 20 eyes of healthy volunteers, 20 eyes of myopic patients, and 20 eyes from each of the following groups: macular hole, lamellar macular hole, epiretinal membranes, drusen, dry age-related macular degeneration (AMD), neovascular AMD, and vitreomacular traction. A single 12-mm wide swept-source optical coherence tomography image for each of the examined eyes consisting of 1,024 A-scans has been created. The main outcome measure selected was to estimate the presence of suprachoroidal layer, as well as ...

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    7. Spectral domain optical coherence tomography morphology in optic disc pit associated maculopathy

      Spectral domain optical coherence tomography morphology in optic disc pit associated maculopathy

      Purpose: Our purpose was to study the clinical manifestation and course of optic pit maculopathy using Spectral Domain Optical Coherence Tomography (SD- OCT) images. Materials and Methods: We used SD-OCT to examine 20 eyes of 19 patients with a macular detachment in combination with an optic. Results: We observed five different fovea appearances in regard to fluid localization. In five eyes, we recorded changes in the fluid distribution with SD-OCT. In 17/20 eyes, we noted a communication between the perineural and subretinal and/or intraretinal space at the margin of the optic disc. Conclusion: 3-dimensional SD-OCT (3D-SDOCT) scans revealed ...

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    8. Correlation of Choroidal Thickness and Volume Measurements with Axial Length and Age Using Swept Source Optical Coherence Tomography and Optical Low-Coherence Reflectometry

      Correlation of Choroidal Thickness and Volume Measurements with Axial Length and Age Using Swept Source Optical Coherence Tomography and Optical Low-Coherence Reflectometry

      Purpose . To report choroidal thickness and volume in healthy eyes using swept source optical coherence tomography (SS-OCT). Methods . A prospective observational study of 122 patients examined with swept source OCT (DRI-OCT, Topcon, Japan). In each eye, we performed 256 horizontal scans, 12 mm in length and centered on the fovea. We calculated choroidal thickness manually with a built-in caliper and automatically using DRI-OCT mapping software. Choroidal volume was also automatically calculated. We measured axial length with optical low-coherence reflectometry (Lenstar LS 900, Haag-Streit, Switzerland). Results . The choroid has focally increased thickness under the fovea. Choroid was thinnest in the outer ...

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    9. Morphological changes in spectral domain optical coherence tomography guided bevacizumab injections in wet age-related macular degeneration, 12-months results

      Morphological changes in spectral domain optical coherence tomography guided bevacizumab injections in wet age-related macular degeneration, 12-months results

      Purpose: To describe retinal changes during Spectral Domain Optical Coherence Tomography (SD-OCT) guided bevacizumab treatment for neovascular age- related macular degeneration (AMD). Settings and Design: Single center observational study. Materials and Methods: We confirmed wet AMD in 47 eyes of 45 patients by fluorescein angiography and SD-OCT. After bevacizumab injection, we examined the patients at 4-week intervals. During each follow-up control, we performed SD-OCT and a complete ophthalmic examination. Criteria for reinjection were visual acuity loss of more than five ETDRS letters, and/or increase of central retinal thickness, sub-retinal fluid, intra-retinal fluid, pigment epithelium detachment. If reinjection criteria were ...

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    10. Non–Full-Thickness Macular Holes Reassessed With Spectral Domain Optical Coherence Tomography

      Non–Full-Thickness Macular Holes Reassessed With Spectral Domain Optical Coherence Tomography

      Purpose: The aim of this study was to describe spectral domain optical coherence tomography characteristics and evolution of non–full-thickness macular holes, with a bed of retinal tissue present in the outer retinal layers, which the author will henceforth refer to as non–full-thickness macular holes (NFMHs). Methods: Retrospective observational study of 10,239 consecutive spectral domain optical coherence tomographic examinations was conducted, to select patients with idiopathic NFMH. We measured the following parameters: visual acuity, type of NFMH, coexistence of epiretinal membranes, photoreceptor layer defects, central and maximum retinal thickness, and diameters of the fovea defect. Patients with a ...

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    11. Spectral optical coherence tomography in a patient with type I sialidosis

      Spectral optical coherence tomography in a patient with type I sialidosis
      Background: The aim of our study was to analyze spectral optical coherence tomography (SD-OCT) findings in a patient with clinical signs of sialidosis. Case Report: Fluorescein angiography and spectral optical coherence tomography was performed in a 37-year-old woman using a SD-OCT device with axial resolution of 6 µm. Enzyme assay followed. The patient was diagnosed with type I sialidosis by enzymatic assay. Besides a normal angiogram, a thickened nerve fiber layer was observed on spectral optical coherence tomography. Conclusions: The thickened nerve fiber layer was probably caused by accumulation of metabolic products such as sialylated oligosaccharides and glycopeptides, suggesting that ...
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    12. Long-Term Evaluation of Vitreomacular Traction Disorder in Spectral-Domain Optical Coherence Tomography

      Long-Term Evaluation of Vitreomacular Traction Disorder in Spectral-Domain Optical Coherence Tomography
      Purpose: The aim of this article was to estimate the natural course of vitreomacular traction (VMT) disorder using high-resolution spectral-domain optical coherence tomography. Methods: Nineteen eyes of 19 patients with idiopathic symptomatic VMT and who underwent spectral-domain optical coherence tomographic follow-up examinations were included in the retrospective observational study. The average observation period of all patients who underwent the examination was 8 months (±4.4 months). We observed microstructural changes in the macula and the position, length, and vector forces of the attached vitreous in the macular surface. Results: Mean best-corrected visual acuity in the first examination was logarithm of ...
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    13. Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study

      Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study
      Abstract Background  The pathogenesis of macular pseudohole (MPH) is supposed to be different from that of macular lamellar hole (LMH). MPH is thought to be caused by centripetal contraction of previously present epiretinal membrane. LMH is considered to be an effect of abortive process of full-thickness macular hole formation, or a result of de-roofing of a foveal cyst in persistent cystoid macular oedema. In most cases of LMH, epiretinal membranes are present. The aim of this paper is to show that LMH and MPH may have a common origin and that LMH may evolve from MPH as an epiretinal membrane ...
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    14. Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes

      Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes
      Purpose: Large macular holes usually have an increased risk of surgical failure. Up to 44% of large macular holes remain open after 1 surgery. Another 19% to 39% of macular holes are flat-open after surgery. Flat-open macular holes are associated with limited visual acuity. This article presents a modification of the standard macular hole surgery to improve functional and anatomic outcomes in patients with large macular holes.Design: A prospective, randomized clinical trial.Participants: Patients with macular holes larger than 400 μm were included. In group 1, 51 eyes of 40 patients underwent standard 3-port pars plana vitrectomy with air ...
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    15. Continuous changes in macular morphology after macular hole closure visualized with spectral optical coherence tomography

      Continuous changes in macular morphology after macular hole closure visualized with spectral optical coherence tomography
      Background To report on changes in retinal morphology during the 12 months after macular hole surgery. Methods Seventy one eyes of 66 patients after pars plana vitrectomy with ILM peeling and air tamponade were evaluated with spectral OCT for 12 months and additionally before surgery. Macular hole size was measured. On consecutive visits, the size of photoreceptor layer defects and elevation of the outer retinal layers were measured. Additionally, changes in foveal contour, nerve fibre layer defects, and retinal pigment epithelium defects were evaluated. Results Photoreceptor defects were observed in 66 eyes (93%) 1 week after surgery, and in only ...
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    16. High-Speed, High-Resolution Spectral Optical Coherence Tomography in Patients After Vitrectomy With Internal Limiting Membrane Peeling for Proliferative Vitreoretinopathy Retinal Detachment

      Purpose: The purpose of this study was to present the retinal morphology after silicone oil removal in patients after vitrectomy with internal limiting membrane peeling and silicone oil tamponade for proliferative vitreoretinopathy retinal detachment. Methods: Nineteen patients after vitrectomy or retinotomy with internal limiting membrane peeling for proliferative vitreoretinopathy retinal detachment were included in this study. All patients were interviewed, and an ophthalmologic examination was performed pre- and postoperatively. Fifteen months after silicone oil removal, all patients were examined with spectral optical coherence tomography Copernicus. Results: Visual acuities determined at the final follow-up visit were from light perception to 20 ...
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    17. A study of macular hole formation by serial spectral optical coherence tomography

      Background: The purpose of this paper is to evaluate changes of the vitreoretinal interface in fellow eyes of eyes with a macular hole and to study early stages of macular hole formation by spectral optical coherence tomography (SOCT).Methods: A prospective study of 131 consecutive patients with history of macular hole. Serial SOCT examinations were performed on the fellow eyes four times during a 6-month observation period. Progression of foveal changes and formation of macular hole in the fellow eyes were studied.Results: Seven distinct abnormalities in the foveal region were noted in 70 of the fellow eyes (53.4 ...
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    18. Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study

      Abstract Purpose  The aim of this paper is to evaluate the retinal structure after macular hole surgery and to study the correlation of structural findings with final functional outcomes, using high-speed, high-resolution spectral optical coherence tomography (SOCT). Methods  Sixty-eight eyes of 60 patients with full-thickness macular holes were included in the study. All patients underwent pars plana vitrectomy with trypan blue staining and internal limiting membrane (ILM) peeling. Patients were evaluated by SOCT, with 6 μm axial and 12–18 μm transverse resolution and three-dimensional images of the retina. Results  There were four different types of macular hole closure: U-shape ...
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    1-18 of 18
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    1. (18 articles) Janusz Michalewski
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    Continuous changes in macular morphology after macular hole closure visualized with spectral optical coherence tomography Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study Long-Term Evaluation of Vitreomacular Traction Disorder in Spectral-Domain Optical Coherence Tomography Spectral optical coherence tomography in a patient with type I sialidosis Non–Full-Thickness Macular Holes Reassessed With Spectral Domain Optical Coherence Tomography Swept-Source optical coherence tomography correlations between retina and choroid before and after vitrectomy for epiretinal membranes Optical coherence tomography angiography in glaucoma Handheld optical coherence tomography for clinical assessment of dental plaque and gingiva Characterisation of macular superficial vessel density alteration in preclinical ethambutol-induced optic neuropathy using optical coherence tomography angiography Three-dimensional spatial reconstruction of coronary arteries based on fusion of intravascular optical coherence tomography and coronary angiography Dynamic-range compression and contrast enhancement in swept-source optical coherence tomography systems with a frequency gain compensation amplifier