1. Articles from Cheng-Yu Lee

    1-4 of 4
    1. Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser

      Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser

      In this study, a Q-switch pumped supercontinuum laser (QS-SCL) is used as a light source for in vivo imaging via ultrahigh-resolution optical coherence tomography and angiography (UHR-OCT/OCTA). For this purpose, an OCT system based on a spectral-domain detection scheme is constructed, and a spectrometer with a spectral range of 635 − 875 nm is designed. The effective full-width at half maximum of spectrum covers 150 nm, and the corresponding axial and transverse resolutions are 2 and 10 µm in air, respectively. The relative intensity noise of the QS-SCL and mode-locked SCL is quantitatively compared. Furthermore, a special processing algorithm is ...

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    2. Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography

      Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography

      In this study, we demonstrated the feasibility of using a handheld optical coherence tomography (OCT) for in vivo visualizations of the microstructural and microvascular features of various oral mucosal types. To scan arbitrary locations of the oral mucosa, a scanning probe was developed, composed of a probe body fabricated by a 3D printer, miniaturized two-axis galvanometer, relay lenses, and reflective prism. With a 3D printing technique, the probe weight and the system volume were greatly reduced, enabling the effective improvement of imaging artifacts from unconscious motion and system complexity. Additionally, in our design, the distal end of the probe can ...

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    3. Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe

      Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe

      Biomedical materials have different optical properties (e.g. absorption) for different wavelengths. Therefore, probing biomedical materials with multiple wavelengths not only can get in-depth understanding of the detected biomedical materials but also can differentiate the detected biomedical materials. To achieve this purpose, in this conference paper, we present our initial results of building up a portable multiple-wavelength biomedical sensing system. At this initial phase, we assembled this kind of system with multiple wavelengths of light sources and photodetectors and preliminarily tested the absorbance of the glucose solutions with different concentrations. The result shows good linearity of the absorbance of the ...

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    4. Noninvasive imaging of oral mucosae with optical coherence tomography

      Noninvasive imaging of oral mucosae with optical coherence tomography

      In this study, a swept-source optical coherence tomography (OCT) system is developed for in vivo visualization of structural and vascular morphology oral mucosa. For simplification of optical probe fabrication, probe weight, and system setup, the body of the scanning probe is fabricated by a 3D printer to fix the optical components and the mechanical scanning device, and a partially reflective slide is attached at the output end of probe to achieve a common-path configuration. Aside from providing the ability of 3D structural imaging with the developed system, 3D vascular images of oral mucosa can be simultaneously obtained. Then, different locations ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) Chang Gung University
    2. (3 articles) National Taiwan University
    3. (2 articles) Zhejiang University
    4. (1 articles) Northwestern University
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    Noninvasive imaging of oral mucosae with optical coherence tomography Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser Influence of scan direction on subfoveal choroidal vascularity index using optical coherence tomography Subthreshold Nanosecond Laser for Non-resolving Central Serous Chorioretinopathy: A Double-masked Sham-controlled Randomised Trial Optical Coherence Tomography Angiography (OCTA) to Assess Cardiac Output and Cerebral Perfusion at the Time of Children's Cardiac Surgery Recent advances in optical coherence tomography for anterior segment imaging in small animals and their clinical implications Intraoperative optical coherence tomography-guided donor corneal tissue assessment and preparation Peripapillary and fovea avascular zone optical coherence tomography angiography parameters in exfoliation glaucoma versus primary open-angle glaucoma versus healthy eyes Comparison of the proposed DCNN model with standard CNN architectures for retinal diseases classification Massachusetts General Hosptial Receives NIH Grant for Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided Biopsy