1. Articles from Chunyang Zhe

    1-2 of 2
    1. Role of Optical Coherence Tomography in Diagnosis and Treatment of Patients with Acute Coronary Syndrome

      Role of Optical Coherence Tomography in Diagnosis and Treatment of Patients with Acute Coronary Syndrome

      Acute coronary syndrome (ACS) is the main cause of death worldwide and the leading cause of disease burden in high-income countries. ACS refers to a constellation of clinical symptoms that are compatible with acute myocardial ischemia. It describes a spectrum of clinical manifestations that result from a common pathophysiological process. The most common cause of ACS are rupture of an atherosclerotic lesion containing a large necrotic core and a thin fibrous cap followed by acute luminal thrombosis. It was thought that a high-resolution imaging modality would be ideal to detect high-risk plaques before their disruption and the formation of an ...

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    2. Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study

      Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study

      Background Plaque rupture and erosion are the 2 most common mechanisms for acute coronary syndromes. However, the outcome of these 2 distinct pathologies in patients with acute coronary syndromes has never been studied. Methods and Results We retrospectively studied 141 patients with acute coronary syndromes who underwent optical coherence tomography ( OCT ) imaging of the culprit lesion prior to stenting from the Massachusetts General Hospital OCT Registry. Management (stent versus no stent), poststent OCT findings, and outcomes were compared. Among the 141 culprit lesions, rupture was found in 79 (56%) patients and erosion in 62 (44%). Stent implantation was performed in ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Harbin Medical University
    2. (2 articles) Bo Yu
    3. (2 articles) Haibo Jia
    4. (1 articles) Massachusetts General Hospital
    5. (1 articles) Harvard University
    6. (1 articles) Tsunenari Soeda
    7. (1 articles) Yan Wang
    8. (1 articles) Ik-Kyung Jang
    9. (1 articles) Shaosong Zhang
    10. (1 articles) Zhao Wang
    11. (1 articles) Duke University
    12. (1 articles) National Institutes of Health
    13. (1 articles) Massachusetts General Hospital
    14. (1 articles) Capital Medical University
    15. (1 articles) Osaka University
    16. (1 articles) Tokyo Medical & Dental University
    17. (1 articles) FDA
    18. (1 articles) Cleveland Clinic
    19. (1 articles) University College London
    20. (1 articles) University of Bonn
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