1. Articles from Alex I. Vitkin

    1-2 of 2
    1. Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers in the development of the atherosclerotic plaque (AP). The study shows potential of CP OCT for the assessment of collagen and elastin fibers condition in atherosclerotic arteries. Specifically, the additional information afforded by CP OCT, related to birefringence and cross-scattering properties of arterial tissues, may improve the robustness and accuracy of assessment about the microstructure and composition of the plaque for different stages of atherosclerosis.

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    2. In vivo Optical Coherence Tomography Imaging of Preinvasive Bronchial Lesions

      Purpose: Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extracellular structures at and below tissue surface. The objective of the study was to determine if OCT could characterize preneoplastic changes in the bronchial epithelium identified by autofluorescence bronchoscopy. Experimental Design: A 1.5-mm fiberoptic probe was inserted via a bronchoscope into the airways of 138 volunteer heavy smokers participating in a chemoprevention trial and 10 patients with lung cancer to evaluate areas that were found to be normal or abnormal on autofluorescence bronchoscopy. Radial scanning of the airways was done to generate OCT images ...
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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Toronto
    2. (2 articles) I. Alex Vitkin
    3. (1 articles) British Columbia Cancer Agency
    4. (1 articles) UT Southwestern Medical Center
    5. (1 articles) University of British Columbia
    6. (1 articles) Ontario Cancer Institute
    7. (1 articles) Felix I. Feldchtein
    8. (1 articles) Stephen Lam
    9. (1 articles) Victor X. D. Yang
    10. (1 articles) Beau A. Standish
    11. (1 articles) Duke University
    12. (1 articles) Adam Wax
    13. (1 articles) Hrebesh M. Subhash
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