1. Articles from Alex I. Vitkin

    1-2 of 2
    1. Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers in the development of the atherosclerotic plaque (AP). The study shows potential of CP OCT for the assessment of collagen and elastin fibers condition in atherosclerotic arteries. Specifically, the additional information afforded by CP OCT, related to birefringence and cross-scattering properties of arterial tissues, may improve the robustness and accuracy of assessment about the microstructure and composition of the plaque for different stages of atherosclerosis.

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    2. In vivo Optical Coherence Tomography Imaging of Preinvasive Bronchial Lesions

      Purpose: Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extracellular structures at and below tissue surface. The objective of the study was to determine if OCT could characterize preneoplastic changes in the bronchial epithelium identified by autofluorescence bronchoscopy. Experimental Design: A 1.5-mm fiberoptic probe was inserted via a bronchoscope into the airways of 138 volunteer heavy smokers participating in a chemoprevention trial and 10 patients with lung cancer to evaluate areas that were found to be normal or abnormal on autofluorescence bronchoscopy. Radial scanning of the airways was done to generate OCT images ...
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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Toronto
    2. (2 articles) I. Alex Vitkin
    3. (1 articles) British Columbia Cancer Agency
    4. (1 articles) UT Southwestern Medical Center
    5. (1 articles) University of British Columbia
    6. (1 articles) Ontario Cancer Institute
    7. (1 articles) Felix I. Feldchtein
    8. (1 articles) Stephen Lam
    9. (1 articles) Victor X. D. Yang
    10. (1 articles) Beau A. Standish
    11. (1 articles) National Taiwan University
    12. (1 articles) Singapore Eye Research Institute
    13. (1 articles) Columbia University
    14. (1 articles) Seoul National University
    15. (1 articles) UT Southwestern Medical Center
    16. (1 articles) Donald C. Hood
    17. (1 articles) K. Bailey Freund
    18. (1 articles) Carl Zeiss Meditec
    19. (1 articles) Apollo Medical Optics
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    Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice Optical coherence tomography characteristics of taxane-induced macular edema and other multimodal imaging findings Comparison of different morphologies of choroidal neovascularization evaluated by optical coherence tomography angiography in age‐related macular degeneration The Use of Optical Coherence Tomography Angiography in the Diagnosis of Inflammatory Type 1 Choroidal Neovascularization Secondary to Tuberculosis: A Case Report Improving the Detection of Glaucoma and Its Progression: A Topographical Approach Vulnerability Zone of Glaucoma Progression in Combined Wide-field Optical Coherence Tomography Event-based Progression Analysis The Application of Non-invasive and Cellular Level Resolution Fullfield Optical Coherence Tomography: Establishment and Analysis of Subcutaneous Cellular Level Image Database of Anatomical Locations in Healthy Volunteers and Evaluation of Usability Anterior Segment Optical Coherence Tomography (AS-OCT) Guided Reversal of Edematous Punctal Occlusion Optical coherence tomography angiography markers associated with treatment response in neovascular age-related macular degeneration Anterior segment optical coherence tomography imaging in peripheral ulcerative keratitis, a corneal structural description Morphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography