1. Articles from Lizzy Wijmans

    1-2 of 2
    1. Optical coherence tomography (OCT) in patients with acute respiratory failure on the ICU

      Optical coherence tomography (OCT) in patients with acute respiratory failure on the ICU

      Introduction: Differentiating ARDS from other forms of respiratory failure can be difficult. By advancing an optic fiber through a diagnostic bronchoscope, followed by an automatic pullback mechanism, OCT enables real-time 3D imaging of the alveolar compartment and peripheral airways. Aim: To investigate feasibility of bronchoscopic OCT, and to describe different OCT patterns of the alveolar compartment in mechanically ventilated patients. Methods: Observational study of OCT imaging in mechanically ventilated patients for non-resolving acute respiratory failure with an indication for diagnostic bronchoscopy. Results: 9 patients were included with clinical features of acute respiratory failure and bilateral pulmonary infiltrates not fully explained ...

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    2. Optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases

      Optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases

      Purpose of review: Current imaging techniques (X-ray, computed tomography scan, ultrasound) have limitations in the identification and quantification of pulmonary diseases, in particular, on highly detailed level. The purpose of this review is to provide an overview of the current knowledge of innovative light- and laser-based imaging techniques that might fill this gap. Recent findings: Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are high-resolution imaging techniques, which, combined with bronchoscopy, provide 'near histology' detailed imaging of the airway wall, lung parenchyma, mediastinal lymph nodes, and pulmonary vasculature. This article reviews the technical background of OCT and CLE, summarizes ...

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    1-2 of 2
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    1. (1 articles) Academic Medical Center at the University of Amsterdam
    2. (1 articles) Daniël M. de Bruin
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