1. Articles from Bethany Mitchell

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    1. Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography

      Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography

      Measurement of sub-clinical atopic dermatitis (AD) is important for determining how long therapies should be continued after clinical clearance of visible AD lesions. An important biomarker of subclinical AD is epidermal hypertrophy, the structural measures of which often make optical coherence tomography (OCT) challenging due to the lack of a clearly delineated dermal-epidermal junction in AD patients. Alternatively, angiographic OCT measurements of vascular depth and morphology may represent a robust biomarker for quantifying the severity of clinical and sub clinical AD. To investigate this, angiographic data sets were acquired from 32 patients with a range of AD severities. Deeper vascular ...

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    2. Characterizing the microcirculation of atopic dermatitis using angiographic optical coherence tomography

      Characterizing the microcirculation of atopic dermatitis using angiographic optical coherence tomography

      Background and Aim: With inflammatory skin conditions such as atopic dermatitis (AD), epidermal thickness is mediated by both pathological hyperplasia and atrophy such as that resulting from corticosteroid treatment. Such changes are likely to influence the depth and shape of the underlying microcirculation. Optical coherence tomography (OCT) provides a non-invasive view into the tissue, however structural measures of epidermal thickness are made challenging due to the lack of a delineated dermal-epidermal junction in AD patients. Instead, angiographic extensions to OCT may allow for direct measurement of vascular depth, potentially presenting a more robust method of estimating the degree of epidermal ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Sheffield
    2. (2 articles) Steven J. Matcher
    3. (1 articles) Institute of Applied Physics
    4. (1 articles) Center for Ophthalmic Optics and Lasers
    5. (1 articles) Oregon Health & Science University
    6. (1 articles) National Eye Institute
    7. (1 articles) Dmitry A. Terpelov
    8. (1 articles) Grigory V. Gelikonov
    9. (1 articles) David Huang
    10. (1 articles) Valentin M. Gelikonov
    11. (1 articles) Pavel A. Shilyagin
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