Articles from Steven Ivers

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  1. Hemodynamic measurements from individual blood cells in early mammalian embryos with Doppler swept source OCT

    Explore Article opticsinfobase.org (Mar 18 2009) Cardiology , Doppler

    Hemodynamic measurements from individual blood cells in early mammalian embryos with Doppler swept source OCT The most common and lethal birth defects affect the cardiovascular (CV) system. The mouse is a superior model for identifying and understanding mammalian CV birth defects, but there is a great need for tools that can detect early and subtle deficiencies in cardiac function in mouse embryos. We combined swept source optical coherence tomography (SS-OCT) with live mouse embryo culture protocols to generate structural two-dimensional and three-dimensional imaging and hemodynamic measurements in a live 8.5 day embryo just a few hours after the beginning of a heartbeat. Our data show that individual circulating blood cells can be visualized with structural ... (Read Full Article)

    Comment on Article Mentions:   Kirill V. Larin   Baylor College of Medicine   University of Houston

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