1. Articles from Yu-Hsuan Liu

    1-2 of 2
    1. Contrast-enhanced optical coherence microangiography with acoustic-actuated microbubbles

      Contrast-enhanced optical coherence microangiography with acoustic-actuated microbubbles

      In this study, we propose to use gas-filled microbubbles (MBs) simultaneously actuated by the acoustic wave to enhance the imaging contrast of optical coherence tomography (OCT)-based angiography. In the phantom experiments, MBs can result in stronger backscattered intensity, enabling to enhance the contrast of OCT intensity image. Moreover, simultaneous application of low-intensity acoustic wave enables to temporally induce local vibration of particles and MBs in the vessels, resulting in time-variant OCT intensity which can be used for enhancing the contrast of OCT intensitybased angiography. Additionally, different acoustic modes and different acoustic powers to actuate MBs are performed and compared ...

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    2. Acoustic-actuated optical coherence angiography

      Acoustic-actuated optical coherence angiography

      Optical coherence tomography (OCT) angiography requires high sensitivity and image penetration for detailed microvascular monitoring. Unfortunately, no effective contrast-medium-enhanced scheme is currently available for imaging improvement. We here propose the simultaneous use of gas-filled microbubbles (MBs) and acoustic actuation to enhance the imaging contrast of OCT angiography. OCT-synchronized acoustic actuation was applied in the presence of MBs, and different moving object tracking angiographic algorithms were tested in in vitro tubing and in vivo mouse experiments. This scheme significantly enhanced the OCT angiography performance, including its sensitivity and penetration, and should advance the utilization of OCT as an effective microvascular diagnostic ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Chang Gung University
    2. (1 articles) Tsinghua University
    3. (1 articles) University of Bologna
    4. (1 articles) University of Cambridge
    5. (1 articles) FDA
    6. (1 articles) Notal Vision
    7. (1 articles) Topcon Medical Systems
    8. (1 articles) Tomey Corporation
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