1. Articles from Benjamin Y. Xu

    1-9 of 9
    1. Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

      Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

      Purpose : To assess the repeatability and agreement of ocular biometric parameters measured using the Tomey CASIA SS-1000 and Heidelberg ANTERION anterior segment optical coherence tomography (AS-OCT) devices. Methods : Both eyes of subjects 18 years of age or older were scanned three times with the CASIA and ANTERION under standardized dark lighting. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan. Pupillary diameter (PD) was within 15% for all pairwise comparisons. Anterior chamber depth, lens vault, anterior chamber width, angle opening distance, trabecular iris space area, and scleral spur angle (SSA500) were measured using manufacturer-provided ...

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    2. Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study

      Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study

      Purpose : To develop a deep neural network that detects the scleral spur in anterior segment optical coherence tomography (AS-OCT) images. Methods : Participants in the Chinese American Eye Study, a population-based study in Los Angeles, California, underwent complete ocular examinations, including AS-OCT imaging with the Tomey CASIA SS-1000. One human expert grader provided reference labels of scleral spur locations in all images. A convolutional neural network (CNN)-based on the ResNet-18 architecture was developed to detect the scleral spur in each image. Performance of the CNN model was assessed by calculating prediction errors, defined as the difference between the Cartesian coordinates ...

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    3. Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research

      Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research

      Anterior segment optical coherence tomography (ASOCT) is a non-contact imaging technique that produces high-resolution images and quantitative measurements of the anterior segment and its anatomical structures. There has been rapid development of OCT technology over the past 2 decades, with the transition from time-domain to Fourier-domain OCT devices. By integrating these advancements in OCT technology, AS-OCT devices have evolved into versatile clinical and research tools for studies of the anterior segment and ocular surface. The primary purpose of this article was to review OCT technology and AS-OCT devices as well as applications of AS-OCT for clinical practice and scientific research ...

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    4. Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries

      Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries

      Precis: When comparing 4.5×4.5 mm to 6.0×6.0 mm optical coherence tomography angiography scans of the radial peripapillary capillaries (RPCs) for glaucoma diagnostic capability, there was a trend of 4.5 scans outperforming 6.0 scans, especially for inferior, nasal, and superior quadrants. Objectives: The main purpose of this study was to compare diagnostic ability of peripapillary vessel parameters from 4.5×4.5 mm (4.5) and 6.0×6.0 mm (6.0) spectral-domain optical coherence tomography angiography scans of the RPC in detecting primary open-angle glaucoma from nonglaucoma eyes. Methods: Consecutive patients ...

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    5. Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography

      Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography

      Purpose : To evaluate the relationship between angle dimensions assessed by gonioscopy or EyeCam and anterior segment optical coherence tomography (AS-OCT). Methods : Subjects aged 50 years or older were recruited from the Chinese American Eye Study (CHES). Each subject underwent a complete ocular exam, including gonioscopy, AS-OCT, and EyeCam. Angle closure was defined as three or more quadrants in which pigmented trabecular meshwork could not be visualized. Angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), trabecular iris angle (TIA), and scleral spur angle (SSA) were measured in each AS-OCT image. Results : 709 eyes (272 angle closure ...

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    6. Correlation Between Intraocular Pressure and Angle Configuration Measured by Optical Coherence Tomography: The Chinese American Eye Study

      Correlation Between Intraocular Pressure and Angle Configuration Measured by Optical Coherence Tomography: The Chinese American Eye Study

      PURPOSE To characterize the relationship between angle configuration measured by anterior segment optical coherence tomography (AS-OCT) and intraocular pressure (IOP). DESIGN Cross-sectional study. PARTICIPANTS Subjects aged 50 years or older were identified from the Chinese American Eye Study (CHES), a population-based epidemiological study in Los Angeles, CA. METHODS Each subject underwent a complete ocular exam including Goldmann applanation tonometry, gonioscopy, and AS-OCT imaging. Four AS-OCT images were analyzed per eye and parameters describing angle configuration were measured, including angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), trabecular iris angle (TIA), and scleral spur angle (SSA ...

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      Mentions: Rohit Varma UCLA
    7. Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters

      Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters

      Purpose: To examine the diurnal variation of static and dynamic anterior segment parameters in young, healthy eyes by comparing anterior segment optical coherence tomography (AS-OCT) measurements obtained in the morning and evening and also in the light and dark. Methods: Twenty-two subjects ranging from ages 19 to 47 years with no past ocular history were selected (12 male, 10 female; mean age 34.2 y). Imaging was performed with the Tomey CASIA2 AS-OCT device in two fixed lighting environments, light and dark, between the hours of 0830 to 1000 and 1730 to 1900. Four AS-OCT images were analyzed per eye ...

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    8. Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices

      Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices

      Purpose: To assess the reproducibility and agreement of measurement values obtained from the Tomey CASIA2 and Heidelberg Spectralis OCT2 anterior segment optical coherence tomography (AS-OCT) devices. Methods: Twenty eyes from ten subjects ranging from age 28 to 45 years with no history of eye conditions or intraocular surgery were included. Two scans were obtained with each device in a standardized dark-room environment after a period of dark adaptation. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan. Lens vault (LV), pupil diameter (PD), anterior chamber width (ACW), angle opening distance (AOD), trabecular iris space ...

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    9. Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study

      Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study

      Purpose : The purpose of this study was to evaluate the benefit of analyzing an increased number of anterior segment optical coherence tomography (AS-OCT) images on measurement values of various anterior segment parameters. Methods : Subjects for this cross-sectional study were recruited from the Chinese American Eye Study (CHES), a population-based study in Los Angeles, CA. Thirty-two AS-OCT images were acquired from one eye each of 83 consecutive subjects. Sixteen parameters were analyzed in each image, including angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), trabecular iris angle (TIA), scleral spur angle (SSAngle), lens vault (LV), pupillary ...

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      Mentions: Rohit Varma UCLA
    1-9 of 9
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    Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters Correlation Between Intraocular Pressure and Angle Configuration Measured by Optical Coherence Tomography: The Chinese American Eye Study Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices A Generic Framework for Fourier-Domain Optical Coherence Tomography Imaging: Software Architecture and Hardware Implementations Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry Relative retinal flow velocity detection using optical coherence tomography angiography imaging