1. Articles from Kasra A. Rezaei

    1-12 of 12

    1. Quantitative Handheld Swept-Source Optical Coherence Tomography Angiography in Awake Preterm and Full-Term Infants

      Explore TVST Journal Ophthalmology
      Quantitative Handheld Swept-Source Optical Coherence Tomography Angiography in Awake Preterm and Full-Term Infants

      Purpose : To compare retinal vascular parameters acquired by handheld swept-source optical coherence tomography angiography (SS-OCTA) between nonsedated preterm and full-term infants. Methods : Preterm and full-term infants at the University of Washington Medical Center were enrolled. Retinal angiograms (nominal size ∼7 × 7 mm 2 ) were obtained at each routine retinopathy of prematurity (ROP) screening session for preterms and once during the first 72 hours of life for full-terms. Macular vessel area density and nonperfusion area were evaluated on the binarized vasculature map in both small (1.5 × 1.5 mm) and large (3 × 3 mm) quadrants. Average vessel diameter and tortuosity ...

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      Mentions: Ruikang K. Wang University of Dundee

    2. Quantitative assessment of choriocapillaris flow deficits in diabetic retinopathy: A swept-source optical coherence tomography angiography study

      Explore Journals | PLOS Ophthalmology
      Quantitative assessment of choriocapillaris flow deficits in diabetic retinopathy: A swept-source optical coherence tomography angiography study

      Purpose To quantitatively assess choriocapillaris (CC) flow deficits in eyes with diabetic retinopathy (DR) using swept-source optical coherence tomography angiography (SS-OCTA). Methods Diabetic subjects with different stages of DR and age-matched healthy subjects were recruited and imaged with SS-OCTA. The en face CC blood flow images were generated using previously published and validated algorithms. The percentage of CC flow deficits (FD%) and the mean CC flow deficit size were calculated in a 5-mm-diameter circle centered on the fovea from the 6×6-mm scans. Results Forty-five diabetic subjects and 27 control subjects were included in the study. The CC FD% in ...

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      Mentions: National Institutes of Health University of Washington Carl Zeiss Meditec

    3. Ultra-Widefield Protocol Enhances Automated Classification of Diabetic Retinopathy Severity with Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Ultra-Widefield Protocol Enhances Automated Classification of Diabetic Retinopathy Severity with Optical Coherence Tomography Angiography

      Purpose To assess the diagnostic utility of retinal nonperfusion to classify eyes based on diabetic retinopathy (DR) severity on optical coherence tomography angiography (OCTA). To determine whether wider field of view (FOV) OCTA protocols enhance the diagnostic utility of retinal nonperfusion in the classification of DR severity. Design Retrospective cross-sectional study Subjects Diabetic patients undergoing ultra-widefield OCTA imaging at one academic retina practice Methods Ultra-widefield OCTA images with 100 degree FOV were obtained from 60 eyes. Eyes were grouped as diabetes without retinopathy (DWR), nonproliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR). The ratio of nonperfusion (RNP) was expressed ...

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      Mentions: University of Washington Ruikang K. Wang

    4. Handheld swept-source optical coherence tomography with angiography in awake premature neonates

      Explore Home Ophthalmology
      Handheld swept-source optical coherence tomography with angiography in awake premature neonates

      Background: Retinopathy of prematurity (ROP) can lead to retinal detachment and severe vision loss and is a common cause of childhood blindness. Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can be used to detect potential abnormalities in the microvasculature in this population. The objective of this study is to assess the feasibility of a newly developed handheld swept source OCT (SS-OCT) device to successfully acquire structural vitreoretinal and retinal microvascular images in awake premature infants. Methods: OCT and OCTA images were acquired at the time of routine ROP examinations from awake, unsedated preterm infants in the ...

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      Mentions: University of Washington Ruikang K. Wang

    5. Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography

      Explore LWW Online Ophthalmology
      Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography

      Purpose: To use optical coherence tomography angiography (OCTA) to evaluate the changes in optic nerve head perfusion following intravitreal antivascular endothelial growth factor injections. Methods: Preinjection and postinjection intraocular pressure (IOP) and OCTA images were taken of both the injected and uninjected fellow eyes. Results: Mean preinjection IOP was 16.6±4.7 mm Hg, which increased to a mean of 40.3±13.0 mm Hg ( P <0.0001) during the first postinjection image and remained elevated at 36.1±11.5 mm Hg ( P <0.0001) during the second postinjection image. Although no significant change was observed in ...

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      Mentions: University of Washington Ruikang K. Wang

    6. Ultra-wide optical coherence tomography angiography in diabetic retinopathy

      Explore Home Ophthalmology
      Ultra-wide optical coherence tomography angiography in diabetic retinopathy

      Background: To implement an ultra-wide optical coherence tomography angiography imaging (UW-OCTA) modality in eyes with diabetic retinopathy (DR) with the aim of quantifying the burden of microvascular disease at baseline and subsequent clinic visits. Methods: UW-OCTA was implemented on a 1,060 nm swept source (SS) OCTA engine running at 100 kHz A-line rate with a motion tracking mechanism. A montage scanning protocol was used to capture a 100-degree field of view (FOV) using a 4×4 grid of sixteen total individual 6×6 mm 2 scans. Typical OCTA images with a FOV of 3×3, 6×6 and 12 ...

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      Mentions: University of Washington Ruikang K. Wang

    7. How OCT angiography is improving our view of diabetic retinopathy

      Explore Retina Specialist Ophthalmology
      How OCT angiography is improving our view of diabetic retinopathy

      The Early Treatment Diabetic Retinopathy Study (ETDRS) established and refined the current clinical grading of diabetic r etinopathy that retina specialists use as an adaptation of the Modified Airlie House Classification. The parameters of the grading system rely primarily on identifying somewhat indirect signs of microvascular ischemic disease that include retinal hemorrhages, venous beading, intraretinal microvascular abnormalities or preretinal neovascularization. However, identifying indirect signs of microvascular disease is fraught with challenges in ensuring reproducibility among different observers and operators, which may introduce error into research or clinical settings. ETDRS made attempts to measure and minimize this variability and found that ...

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    8. Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Explore Healio.com Ophthalmology
      Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 × 9 mm 2 . The en face maximum projection was used to generate 2-D angiograms of different layers with color-coded images. Variable levels of perfusion within the lesion were identified, which correlate well ...

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      Mentions: University of Washington Ruikang K. Wang

    9. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Explore jovr.org Ophthalmology
      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      iabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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      Mentions: University of Washington

    10. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Explore jovr.org Ophthalmology
      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Diabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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    11. Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity

      Explore BJO Online Ophthalmology
      Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity

      Aim To evaluate the association between retinal capillary non-perfusion and diabetic retinopathy (DR) severity using optical coherence tomography-based microangiography (OMAG). Methods 33 patients (51 eyes) with a history of diabetes underwent imaging with a 68 kHz Cirrus-5000 spectral domain OMAG prototype. Demographic and clinical characteristics were collected. The perfusion index (PI) was defined as per cent coverage of area by retinal vessels with flow, measured within a minimum of 6.8×6.8 mm 2 OMAG scan. The PI in each ETDRS zone was analysed using an automated algorithm. Univariate and multivariate analyses were used to determine the degree of ...

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      Mentions: University of Washington Ruikang K. Wang

    12. Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Purpose To visualize and quantify the size and vessel density of macular neovascularization (MNV) using optical coherence tomography angiography (OCTA) with a projection artifact removal algorithm. Design Multicenter, observational study. Participants Subjects with MNV in ≥1 eye. Methods Patients were imaged using either a swept-source OCTA prototype system or a spectral-domain OCTA prototype system. The optical microangiography (OMAG) algorithm was used to generate the OCTA images. Projection artifacts from the overlying retinal circulation were removed from the OMAG OCTA images using a novel algorithm. After removal of the projection artifacts from the OCTA images, we assessed the size and vascularity ...

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      Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
    1-12 of 12
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    1. (9 articles) University of Washington
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    Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma How OCT angiography is improving our view of diabetic retinopathy Ultra-wide optical coherence tomography angiography in diabetic retinopathy Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography Handheld swept-source optical coherence tomography with angiography in awake premature neonates Ultra-Widefield Protocol Enhances Automated Classification of Diabetic Retinopathy Severity with Optical Coherence Tomography Angiography CT texture analysis of vulnerable plaques on optical coherence tomography Peri-stent contrast staining after ultrathin, biodegradable polymer sirolimus-eluting stent implantation: findings from optical coherence tomography and coronary angioscopy