1. Articles from Kasra A. Rezaei

    1-8 of 8
    1. Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography

      Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography

      Purpose: To use optical coherence tomography angiography (OCTA) to evaluate the changes in optic nerve head perfusion following intravitreal antivascular endothelial growth factor injections. Methods: Preinjection and postinjection intraocular pressure (IOP) and OCTA images were taken of both the injected and uninjected fellow eyes. Results: Mean preinjection IOP was 16.6±4.7 mm Hg, which increased to a mean of 40.3±13.0 mm Hg ( P <0.0001) during the first postinjection image and remained elevated at 36.1±11.5 mm Hg ( P <0.0001) during the second postinjection image. Although no significant change was observed in ...

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    2. Ultra-wide optical coherence tomography angiography in diabetic retinopathy

      Ultra-wide optical coherence tomography angiography in diabetic retinopathy

      Background: To implement an ultra-wide optical coherence tomography angiography imaging (UW-OCTA) modality in eyes with diabetic retinopathy (DR) with the aim of quantifying the burden of microvascular disease at baseline and subsequent clinic visits. Methods: UW-OCTA was implemented on a 1,060 nm swept source (SS) OCTA engine running at 100 kHz A-line rate with a motion tracking mechanism. A montage scanning protocol was used to capture a 100-degree field of view (FOV) using a 4×4 grid of sixteen total individual 6×6 mm 2 scans. Typical OCTA images with a FOV of 3×3, 6×6 and 12 ...

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    3. How OCT angiography is improving our view of diabetic retinopathy

      How OCT angiography is improving our view of diabetic retinopathy

      The Early Treatment Diabetic Retinopathy Study (ETDRS) established and refined the current clinical grading of diabetic r etinopathy that retina specialists use as an adaptation of the Modified Airlie House Classification. The parameters of the grading system rely primarily on identifying somewhat indirect signs of microvascular ischemic disease that include retinal hemorrhages, venous beading, intraretinal microvascular abnormalities or preretinal neovascularization. However, identifying indirect signs of microvascular disease is fraught with challenges in ensuring reproducibility among different observers and operators, which may introduce error into research or clinical settings. ETDRS made attempts to measure and minimize this variability and found that ...

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    4. Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 × 9 mm 2 . The en face maximum projection was used to generate 2-D angiograms of different layers with color-coded images. Variable levels of perfusion within the lesion were identified, which correlate well ...

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    5. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      iabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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    6. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Diabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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    7. Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity

      Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity

      Aim To evaluate the association between retinal capillary non-perfusion and diabetic retinopathy (DR) severity using optical coherence tomography-based microangiography (OMAG). Methods 33 patients (51 eyes) with a history of diabetes underwent imaging with a 68 kHz Cirrus-5000 spectral domain OMAG prototype. Demographic and clinical characteristics were collected. The perfusion index (PI) was defined as per cent coverage of area by retinal vessels with flow, measured within a minimum of 6.8×6.8 mm 2 OMAG scan. The PI in each ETDRS zone was analysed using an automated algorithm. Univariate and multivariate analyses were used to determine the degree of ...

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    8. Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography

      Purpose To visualize and quantify the size and vessel density of macular neovascularization (MNV) using optical coherence tomography angiography (OCTA) with a projection artifact removal algorithm. Design Multicenter, observational study. Participants Subjects with MNV in ≥1 eye. Methods Patients were imaged using either a swept-source OCTA prototype system or a spectral-domain OCTA prototype system. The optical microangiography (OMAG) algorithm was used to generate the OCTA images. Projection artifacts from the overlying retinal circulation were removed from the OMAG OCTA images using a novel algorithm. After removal of the projection artifacts from the OCTA images, we assessed the size and vascularity ...

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    1-8 of 8
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    Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography Association between OCT-based microangiography perfusion indices and diabetic retinopathy severity Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma How OCT angiography is improving our view of diabetic retinopathy Ultra-wide optical coherence tomography angiography in diabetic retinopathy Optic Nerve Head Perfusion Before and After Intravitreal Antivascular Growth Factor Injections Using Optical Coherence Tomography-based Microangiography Image contrast correction method in full-field optical coherence tomography Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography Optical coherence tomography angiography characteristics of acute retinal arterial occlusion Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study