1. Articles from K. S. Yashin

    1-3 of 3
    1. Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Determining boundaries of infiltrative glial tumors remains a challenging problem in neurooncology. Optical coherence tomography (OCT) with cross-polarization (CP) visualization is a promising technique as a surgical guidance tool. However, the outcome of the procedures performed under OCT guidance strongly depends on the surgeon’s qualification. Thus, a quantitative method for assessing resection margins with OCT is required. The aim of this study was to develop a robust quantitative approach for CP OCT data to differentiate tumorous from non-tumorous tissues in a rat glioma model. Materials and Methods. The study was carried out on the rats’ brains (n=6) with ...

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    2. Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      The aim of the study was to provide visual and quantitative evaluation of tumorous and normal brain tissue images obtained by cross-polarization optical coherence tomography (CP OCT) in a comparative in vivo and ex vivo study. Materials and Methods. The CP OCT as a non-damaging noninvasive optical method for tissue structure imaging was used in the study. It enables obtaining volumetric images of 2.4×2.4×1.25 mm 3 in size in real time within a short time of 26 s. The objects were tumorous and normal brain tissues of 12 experimental animals (Wistar rats): 4 — intact, 4 ...

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    3. Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)

      Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)

      The aim of the investigation was to evaluate the performance of multimodal OCT (MM OCT) for differential diagnostics of normal and diseased brain tissue using an experimental model of glioblastoma. Materials and Methods. The spectral domain MM OCT device developed at the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia) was used for the study. It provides two modes of investigation: cross-polarization OCT (CP OCT) and microangiographic OCT (MA OCT). The instrument features the following characteristics: rate of information gathering — 20,000 A-scans per second; wavelength — 1.3 µm; shot size — ~4 × 2 mm; lateral ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Institute of Applied Physics
    2. (3 articles) Natalia D. Gladkova
    3. (3 articles) Elena B. Kiseleva
    4. (2 articles) Nizhny Novgorod State Medical Academy
    5. (1 articles) University of Toronto
    6. (1 articles) Grigory V. Gelikonov
    7. (1 articles) Maria M. Karabut
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    Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study) Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study Deep iterative vessel segmentation in OCT angiography Subretinal Drusenoid Deposits and Photoreceptor Loss Detecting Global and Local Progression of Geographic Atrophy by SD-OCT Imaging Ultra-high-resolution SD-OCM imaging with a compact polarization-aligned 840 nm broadband combined-SLED source Sparse Domain Gaussianization for Multi-variate Statistical Modeling of Retinal OCT Images Optical reflectance contrast of micro- and nano-structures revealed with intravital micro-OCT (Thesis) In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography SD-OCT peripapillary nerve fibre layer and ganglion cell complex parameters in glaucoma: principal component analysis Accuracy of optical coherence tomography for diagnosing glaucoma: an overview of systematic reviews