1. Articles from I. A. Medyanik

    1-3 of 3
    1. Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study

      Determining boundaries of infiltrative glial tumors remains a challenging problem in neurooncology. Optical coherence tomography (OCT) with cross-polarization (CP) visualization is a promising technique as a surgical guidance tool. However, the outcome of the procedures performed under OCT guidance strongly depends on the surgeon’s qualification. Thus, a quantitative method for assessing resection margins with OCT is required. The aim of this study was to develop a robust quantitative approach for CP OCT data to differentiate tumorous from non-tumorous tissues in a rat glioma model. Materials and Methods. The study was carried out on the rats’ brains (n=6) with ...

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    2. Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues

      The aim of the study was to provide visual and quantitative evaluation of tumorous and normal brain tissue images obtained by cross-polarization optical coherence tomography (CP OCT) in a comparative in vivo and ex vivo study. Materials and Methods. The CP OCT as a non-damaging noninvasive optical method for tissue structure imaging was used in the study. It enables obtaining volumetric images of 2.4×2.4×1.25 mm 3 in size in real time within a short time of 26 s. The objects were tumorous and normal brain tissues of 12 experimental animals (Wistar rats): 4 — intact, 4 ...

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    3. Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)

      Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)

      The aim of the investigation was to evaluate the performance of multimodal OCT (MM OCT) for differential diagnostics of normal and diseased brain tissue using an experimental model of glioblastoma. Materials and Methods. The spectral domain MM OCT device developed at the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia) was used for the study. It provides two modes of investigation: cross-polarization OCT (CP OCT) and microangiographic OCT (MA OCT). The instrument features the following characteristics: rate of information gathering — 20,000 A-scans per second; wavelength — 1.3 µm; shot size — ~4 × 2 mm; lateral ...

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    1-3 of 3
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    1. (3 articles) Institute of Applied Physics
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    Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study) Cross-Polarization Optical Coherence Tomography in Comparative in vivo and ex vivo Studies of the Optical Properties of Normal and Tumorous Brain Tissues Quantitative Cross-Polarization Optical Coherence Tomography Detection of Infiltrative Tumor Margin in a Rat Glioma Model: a Pilot Study Optical Coherence Tomography Angiography in Myopic Patients Quantification of retinal microvasculature and neurodegeneration changes in branch retinal vein occlusion after resolution of cystoid macular edema on optical coherence tomography angiography Machining head for a laser machining device Quantitative Comparison Of Microvascular Metrics On Three Optical Coherence Tomography Angiography Devices In Chorioretinal Disease Detection of and validation of shadows in intravascular images Automated intravascular plaque classification Detection of stent struts relative to side branches Role of optical coherence tomography for distal left main stem angioplasty Measurement of the Shrinkage of Natural and Simulated Lesions on Root Surfaces using CP-OCT