1. Articles from Silvana Ciardo

    1-9 of 9
    1. Skin aging: clinical aspects and in vivo microscopic patterns observed with reflectance confocal microscopy and optical coherence tomography

      Skin aging: clinical aspects and in vivo microscopic patterns observed with reflectance confocal microscopy and optical coherence tomography

      Background: Few studies have combined high-resolution, non-invasive imaging, such as standardized clinical images, Reflectance Confocal Microscopy (RCM) and Optical Coherence Tomography (OCT), for age-related skin change characterization according to age groups. Objective: To correlate clinical manifestations of aging with skin cytoarchitectural background observed with high-resolution, non-invasive imaging according to age-related skin pattern distribution. Methods: A set of 140 non-pathological facial skin images were retrospectively retrieved from a research database. Subjects, aged between 20-89, were divided into 7 age groups. Clinical features were explored with VISIA, including hyperpigmentation, skin texture, wrinkles, pores and red areas, quantified and expressed as automated absolute ...

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    2. Non-Melanoma Skin Cancer Clearance after Medical Treatment Detected with Noninvasive Skin Imaging: A Systematic Review and Meta-Analysis

      Non-Melanoma Skin Cancer Clearance after Medical Treatment Detected with Noninvasive Skin Imaging: A Systematic Review and Meta-Analysis

      Background/Objectives: Non-melanoma skin cancer (NMSC) treated with nonsurgical therapies can be monitored with noninvasive skin imaging. The precision of dermoscopy, reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) in detecting clearance is unclear. We aim to report the proportion of persisting tumors identified with noninvasive technologies available in the literature. Methods: A systematic literature search was conducted on the PubMed and Cochrane Public Library Databases for articles published prior to November 2021. Statistical analyses were conducted with MedCalc 14.8.1 software. Results: A total of eight studies (352 lesions) reporting noninvasive imaging for NMSC clearance following nonsurgical ...

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    3. Dermoscopy, confocal microscopy and optical coherence tomography features of main inflammatory and autoimmune skin diseases: A systematic review

      Dermoscopy, confocal microscopy and optical coherence tomography features of main inflammatory and autoimmune skin diseases: A systematic review

      Background/objectives: Non-invasive skin imaging features of main skin inflammatory and autoimmune diseases have been reported, although a comprehensive review of their correlation with histopathologic features is currently lacking. Therefore, the aim of this paper was to review the correlation of dermoscopic, reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) criteria of main inflammatory and autoimmune skin diseases with their corresponding histopathologic criteria correlation. Methods: Studies on human subjects affected by main inflammatory and autoimmune diseases, defining the correlation of dermoscopic, RCM or OCT with histopathologic criteria, were included in the review. Five groups of diseases were identified and ...

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    4. Efficacy Assessment of a TCA/H2O2 Compositum for Skin Aging Treatment by Confocal Laser Microscopy and Optical Coherence Tomography

      Efficacy Assessment of a TCA/H2O2 Compositum for Skin Aging Treatment by Confocal Laser Microscopy and Optical Coherence Tomography

      Skin ageing is a complex phenomenon linked to intrinsic and extrinsic factors, such as ultraviolet exposure, smoking, or pollution, 1-4 which involves all skin layers. 5,6,7 Ageing is characterised by a reduction of collagen synthesis, 4,8,9 a decreased hydration, 5,6 epidermal thickness variations 7 , and an accelerated breakdown and disorganization of collagen fibers 4,8,9 as well as loss of skin elasticity.

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    5. A plea for standardization of confocal microscopy and optical coherence tomography parameters to evaluate physiological and para‐physiological skin conditions in cosmetic science

      A plea for standardization of confocal microscopy and optical coherence tomography parameters to evaluate physiological and para‐physiological skin conditions in cosmetic science

      Background: Non-invasive Reflectance Confocal Microscopy (RCM) and Optical Coherence Tomography (OCT) have been extended to the dermo-cosmetic field, for skin pathophysiology understanding and therapeutics monitoring. However, standardized methodology and parameters to interpret structures and changes in these settings are still lacking. Objective: to propose a validated standard methodology and a list of defined parameters for objective non-pathological skin assessments in the cosmetically sensitive cheekbone area of the face. Methods: OCT and RCM quantitative, semi-quantitative, and qualitative features were considered for assessments. Validation process included 50 sets of images divided into 2 age groups. Inter-rater reliability was explored to assess the ...

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    6. Visible characteristics and structural modifications relating to enlarged facial pores

      Visible characteristics and structural modifications relating to enlarged facial pores

      Background Many factors relate to enlargement and visibility of facial pores. However, how enlargement relates to modification of the skin structure is still poorly analysed. Therefore, our aim was to characterise the visible features and the micro‐environment of facial pores. Materials and Methods We recruited 160 women, half of them with normal‐size facial pores, the other half presenting enlarged pores. We analysed their right cheek using standardised photography, in vivo reflectance microscopy and optical coherence tomography. Results If the area of pores is indeed the most differentiating visible characteristic, enlarged facial pores are also denser and more contrasted ...

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    7. Speckled variance optical coherence tomography for the assessment of nail involvement in acrodermatitis continua of Hallopeau: A case study

      Speckled variance optical coherence tomography for the assessment of nail involvement in acrodermatitis continua of Hallopeau: A case study

      Noninvasive techniques for nail imaging would be useful for confirming diagnosis and monitoring treatment response at the microscopic level in patients with nail psoriasis. However, the use of ultrasound and high-resolution magnetic resonance imaging in nail evaluation is limited. Optical coherence tomography (OCT) produces high-resolution images of transversal tissue sections and represents an optimal approach to the study of the nail. This study used a multibeam OCT instrument to produce speckled variance OCT (SV-OCT) blood-flow images, which were used to measure the degree of change over successive scans. Nail changes, inflammation and response to therapy were evaluated in a 75-year-old ...

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    1-9 of 9
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    Speckled variance optical coherence tomography for the assessment of nail involvement in acrodermatitis continua of Hallopeau: A case study A headstrong case of folliculitis decalvans: treatment options and evaluation with dermoscopy, reflectance confocal microscopy and optical coherence tomography Red dye-related tattoo reactions: Could optical coherence tomography be of help? Visible characteristics and structural modifications relating to enlarged facial pores A plea for standardization of confocal microscopy and optical coherence tomography parameters to evaluate physiological and para‐physiological skin conditions in cosmetic science Efficacy Assessment of a TCA/H2O2 Compositum for Skin Aging Treatment by Confocal Laser Microscopy and Optical Coherence Tomography Dermoscopy, confocal microscopy and optical coherence tomography features of main inflammatory and autoimmune skin diseases: A systematic review Non-Melanoma Skin Cancer Clearance after Medical Treatment Detected with Noninvasive Skin Imaging: A Systematic Review and Meta-Analysis Skin aging: clinical aspects and in vivo microscopic patterns observed with reflectance confocal microscopy and optical coherence tomography A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography Quantitative assessment of textural features in the early detection of diabetic retinopathy with optical coherence tomography angiography Line-field confocal optical coherence tomography of fibroepithelioma of Pinkus