1. Articles from Shuyuan Chen

    1-2 of 2
    1. Small HDL Subclass is Associated with Coronary Plaque Stability: An Optical Coherence Tomography Study in Patients with Coronary Artery Disease

      Small HDL Subclass is Associated with Coronary Plaque Stability: An Optical Coherence Tomography Study in Patients with Coronary Artery Disease

      Background The role of high-density lipoprotein (HDL) subclasses in atherosclerotic diseases remains an open question. Previous clinical trials have attempted to explore the predictive effect of HDL subspecies on cardiovascular risk. However, no studies have assessed the connections between these subclasses and characteristics of plaque microstructure. Objective To investigate the relationship of HDL subclasses and coronary plaque stability assessed by optical coherence tomography (OCT). Methods Morphological characteristics of 160 non-target lesions from 85 patients with coronary artery disease were assessed by OCT. High-density lipoprotein (HDL) subclass profiles were analyzed using non-denaturing polyacrylamide gel electrophoresis. Results The plasma levels of small ...

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    2. Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study

      Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study

      This study used optical coherence tomography (OCT) to investigate the effects of systemic methotrexate, in combination with a drug-eluting stent, on in-stent neoatherosclerosis in a rabbit model. Sirolimus-eluting stents were surgically implanted in the right common carotid arteries of 200 male New Zealand White rabbits; the animals received a high-fat diet, beginning one week before stent implantation. Each animal was randomly assigned to 1 of 4 groups, receiving intravenous injections of either methotrexate (0.4 mg/kg) or placebo weekly for 4 or 12 weeks. Stented arterial segments were harvested after stenting for 4 or 12 weeks, and processed for ...

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    1-2 of 2
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    1. (2 articles) Harbin Medical University
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    Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study Small HDL Subclass is Associated with Coronary Plaque Stability: An Optical Coherence Tomography Study in Patients with Coronary Artery Disease New OCT-A device allows imaging of nonsedated infants Are nuclei in stratified squamous epithelium high scattering or low scattering? Efficacy of the proximal optimization technique on crossover stenting in coronary bifurcation lesions in the 3D-OCT bifurcation registry COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study) A new step for volumetric laser endomicroscopy: entering the therapeutic realm of endoscopic mucosal resection Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue Classification of dry age-related macular degeneration and diabetic macular edema from optical coherence tomography images using dictionary learning Ultra-widefield optical coherence tomographic imaging of posterior vitreous in eyes with high myopia Radiofrequency ablation lesion assessment using optical coherence tomography – a proof‐of‐concept study The evaluation of spontaneous Descemet’s membrane reattachment using swept-source optical coherence tomography: a case report