1. Articles from Victor Yang

    1-7 of 7
    1. Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases

      Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases

      Studies evaluating individuals for endothelial injury after endovascular thrombectomy (EVT) have been done by means of retrieved human thrombus, MR vessel-wall imaging, and animal histopathological studies. These techniques have limitations, because MR imaging has insufficient spatial resolution to directly visualize endothelium, and histopathological examinations are performed ex vivo and are unable to provide real-time patterns of injury. The purpose of the current study was to obtain in vivo intraluminal imaging after EVT by using optical coherence tomography (OCT), examining for evidence of endothelial injury in real time. Three consecutive patients with acute basilar artery occlusion underwent OCT imaging immediately after ...

      Read Full Article
    2. Vascular wall stress during intravascular optical coherence tomography imaging

      Vascular wall stress during intravascular optical coherence tomography imaging

      Biomechanical properties of arterial wall is crucial for understanding the changes in the cardiovascular system. Catheters are used during intravascular optical coherence tomography (IVOCT) imaging. The presence of a catheter alters the flow field, pressure distribution and frictional resistance to flow in an artery. In this paper, we first study the transmural stress distribution of the catheterized vessel. COMSOL (COMSOL 4.4) was used to simulate the blood flow induced deformation in a catheterized vessel. Blood is modeled as an incompressible Newtonian fluid. Stress distribution from an three-layer vascular model with an eccentric catheter are simulated, which provides a general ...

      Read Full Article
    3. Digital image correlation–based optical coherence elastography

      Digital image correlation–based optical coherence elastography

      Optical coherence elastography (OCE) provides deformation or material properties, mapping of soft tissue. We aim to develop a robust speckle tracking OCE technique with improved resolution and accuracy. A digital image correlation (DIC)-based OCE technique was developed by combining an advanced DIC algorithm with optical coherence tomography (OCT). System calibration and measurement error evaluation demonstrated that this DIC-based OCE technique had a resolution of ∼ 0.6     μ m displacement and < 0.5 % strain measurement in the axial scan direction. The measured displacement ranged from 0.6 to 150 μ m, obtained via phantom imaging. The capability of the DIC-based OCE technique ...

      Read Full Article
    4. Development of quantitative parameters to assess in-vivo optical coherence tomography images of late oral radiation toxicity patients

      Development of quantitative parameters to assess in-vivo optical coherence tomography images of late oral radiation toxicity patients

      Late oral radiation toxicity is a common condition occurring in a considerable percentage of head and neck cancer patients after radiation therapy which reduces their quality of life. The current examination of these patients is based on a visual inspection of the surface of the oral cavity; however, it is well known that many of the complications start in the subsurface layers before any superficial manifestation. Considering the currently suboptimal examination techniques, we address this clinical problem by using optical coherence tomography (OCT) to monitor the subsurface oral layers with micron-scale resolution images. A spectral-domain OCT system and a specialized ...

      Read Full Article
    5. Optical coherence tomography imaging of preneoplastic lung lesion

      Although autofluorescence bronchoscopy improves the detection rate of high grade dysplasia and carcinoma in-situ compares to white-light examination, the natural history of preneoplastic bronchial lesions is still poorly understood because the biopsy procedure for histological confirmation can mechanically remove these small lesions. The lack of accurate information regarding the spontaneous progression and regression rates of preneoplastic lesions make if difficult to assess the effect of chemoprevention agents. It is therefore important to develop non-biopsy methods that can characterize preneoplastic lesions in the bronchial epithelium. Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extra-cellular structures ...

      Read Full Article
    6. Conducting polymer actuator driven catheter: overview and applications

      In this paper conducting polymer based active catheters are presented. Design considerations along with the promise and challenges associated with conducting polymer driven devices are discussed. A conducting polymer driven intravascular catheter is described briefly and its design challenges such as structural rigidity and angle of bending are studied. Then a detailed description of a polypyrrole based active catheter that is ultimately intended for in-vivo imaging applications will be presented. The active catheter contains an optical fibre and is designed to scan the fibre in two dimensions at a speed of 30 Hz to provide real time imaging. The preliminary ...
      Read Full Article
    7. In vivo Optical Coherence Tomography Imaging of Preinvasive Bronchial Lesions

      Purpose: Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extracellular structures at and below tissue surface. The objective of the study was to determine if OCT could characterize preneoplastic changes in the bronchial epithelium identified by autofluorescence bronchoscopy. Experimental Design: A 1.5-mm fiberoptic probe was inserted via a bronchoscope into the airways of 138 volunteer heavy smokers participating in a chemoprevention trial and 10 patients with lung cancer to evaluate areas that were found to be normal or abnormal on autofluorescence bronchoscopy. Radial scanning of the airways was done to generate OCT images ...
      Read Full Article
    1-7 of 7
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (7 articles) Victor X. D. Yang
    2. (4 articles) University of Toronto
    3. (4 articles) Ryerson University
    4. (3 articles) University of British Columbia
    5. (3 articles) Sunnybrook Health Sciences Centre
    6. (2 articles) British Columbia Cancer Agency
    7. (2 articles) Stephen Lam
    8. (2 articles) Cuiru Sun
    9. (2 articles) I. Alex Vitkin
    10. (2 articles) Beau A. Standish
    11. (2 articles) Massachusetts General Hospital
    12. (1 articles) Harvard University
    13. (1 articles) The Chinese University of Hong Kong
    14. (1 articles) University of Miami
    15. (1 articles) VU University Amsterdam
    16. (1 articles) David A. Boas
    17. (1 articles) Brett E. Bouma
    18. (1 articles) Johannes F. de Boer
    19. (1 articles) Frank D. Verbraak
    20. (1 articles) Apollo Medical Optics
  3. Popular Articles

  4. Picture Gallery

    Development of quantitative parameters to assess in-vivo optical coherence tomography images of late oral radiation toxicity patients Digital image correlation–based optical coherence elastography Vascular wall stress during intravascular optical coherence tomography imaging Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography Examination of retinal vascular density changes via optical coherence tomography angiography in patients with glaucoma 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT The evaluation of juvenile ocular hypertension by optical coherence tomography angiography Superficial capillary perfusion on optical coherence tomography angiography differentiates moderate and severe nonproliferative diabetic retinopathy