1. Articles from Daniel Jaque

    1-2 of 2
    1. Gold nanoshells: Contrast agents for cell imaging by cardiovascular optical coherence tomography

      Gold nanoshells: Contrast agents for cell imaging by cardiovascular optical coherence tomography

      Optical coherence tomography (OCT) has gained considerable attention in interventional cardiovascular medicine and is currently used in clinical settings to assess atherosclerotic lesions and to optimize stent placement. Artery imaging at the cellular level constitutes the first step towards cardiovascular molecular imaging, which represents a major advance in the development of personalized noninvasive therapies. In this work, we demonstrate that cardiovascular OCT can be used to detect individual cells suspended in biocompatible fluids. Importantly, the combination of this catheter-based clinical technique with gold nanoshells (GNSs) as intracellular contrast agents led to a substantial enhancement in the backscattered signal produced by ...

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      Mentions: Fernando Alfonso
    2. Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

      Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

      The potential use of Gold Nanoparticles (GNPs) as contrast agents for clinical intracoronary frequency domain Optical Coherence Tomography (OCT) is here explored. The OCT contrast enhancement caused by GNPs of different sizes and morphologies has been systematically investigated and correlated with their optical properties. Among the different GNPs commercially available with plasmon resonances close to the operating wavelength of intracoronary OCT (1.3 µm), Gold Nanoshells (GNSs) have provided the best OCT contrast due to their largest scattering cross section at this wavelength. Clinical intracoronary OCT catheters are here demonstrated to be capable of three dimensional visualization and real-time tracking ...

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      Mentions: Fernando Alfonso
    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Fernando Alfonso
    2. (1 articles) Medical University of Vienna
    3. (1 articles) University of Florence
    4. (1 articles) UCLA
    5. (1 articles) National Institutes of Health
    6. (1 articles) Shanghai Jiao Tong University
    7. (1 articles) Srinivas R. Sadda
    8. (1 articles) Xincheng Yao
    9. (1 articles) Bo Yu
    10. (1 articles) Qian Li
    11. (1 articles) Heidelberg Engineering
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    Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography Gold nanoshells: Contrast agents for cell imaging by cardiovascular optical coherence tomography In-stent restenosis and longitudinal stent deformation: a case report Microvascular Features of Treated Retinoblastoma Tumors in Children Assessed Using OCTA OCTA characterisation of microvascular retinal alterations in patients with central serous chorioretinopathy Comparative study of the influence of linear and branched alkyltrichlorosilanes on the removal efficiency of polyethylene and polypropylene-based microplastic particles from water Optical Coherence Tomography Angiography for Choroidal Neovascularization and Subretinal Fibrosis in Pseudoxanthoma Elasticum Optical coherence tomography and optical coherence tomography angiography in glaucoma: diagnosis, progression, and correlation with functional tests Morpho-Functional Evaluation of Full-Thickness Macular Holes by the Integration of Optical Coherence Tomography Angiography and Microperimetry Acute changes in ganglion cell layer thickness in ischemic optic neuropathy compared to optic neuritis using optical coherence tomography Microscope-Integrated Optical Coherence Tomography–Guided Autologous Full-Thickness Neurosensory Retinal Autograft for Large Macular Hole–Related Total Retinal Detachment Quantitative Evaluation of the Retinal Vascular Parameters With OCTA in Patients With Behçet Disease Without Ocular Involvement