1. Articles from Thomas J. MacGillivray

    1-2 of 2
    1. The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review

      The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review

      Introduction Discovering non‐invasive and easily acquired biomarkers that are conducive to the accurate diagnosis of dementia is an urgent area of ongoing clinical research. One promising approach is retinal imaging, as there is homology between retinal and cerebral vasculature. Recently, optical coherence tomography angiography (OCT‐A) has emerged as a promising new technology for imaging the microvasculature of the retina. Methods A systematic review and meta‐analysis was conducted to examine the application of OCT‐A in dementia. Results Fourteen studies assessing OCT‐A in preclinical Alzheimer's disease (AD), mild cognitive impairment, or AD were included. Exploratory meta ...

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    2. Modulation of retinal image vasculature analysis to extend utility and provide secondary value from optical coherence tomography imaging

      Modulation of retinal image vasculature analysis to extend utility and provide secondary value from optical coherence tomography imaging

      Retinal image analysis is emerging as a key source of biomarkers of chronic systemic conditions affecting the cardiovascular system and brain. The rapid development and increasing diversity of commercial retinal imaging systems present a challenge to image analysis software providers. In addition, clinicians are looking to extract maximum value from the clinical imaging taking place. We describe how existing and well-established retinal vasculature segmentation and measurement software for fundus camera images has been modulated to analyze scanning laser ophthalmoscope retinal images generated by the dual-modality Heidelberg SPECTRALIS ® instrument, which also features optical coherence tomography.

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Boston University
    2. (2 articles) Massachusetts General Hospital
    3. (1 articles) Nara Medical University
    4. (1 articles) University of Maryland
    5. (1 articles) University of Ulsan
    6. (1 articles) FDA
    7. (1 articles) Duke University
    8. (1 articles) University of Queensland
    9. (1 articles) Cleveland Clinic
    10. (1 articles) Kobe University Graduate School of Medicine
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    Modulation of retinal image vasculature analysis to extend utility and provide secondary value from optical coherence tomography imaging The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images Volumetric characterization of microvasculature in ex vivo human brain samples by serial sectioning optical coherence tomography Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide Retinal changes in bipolar disorder as an endophenotype candidate: Comparison of OCT-detected retinal changes in patients, siblings, and healthy controls Intraoperative optical coherence tomography guided 25G micro-amount trajectory vitrectomy for the treatment of penetrating ocular injury caused by a foreign body in the right eye: A case study Optical coherence tomography angiography reveals paradoxically decreasing choroidal thickness & increasing blood flow in remitting Vogt Koyanagi Harada syndrome A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours Fundus Changes Evaluated by OCTA in Patients With Cerebral Small Vessel Disease and Their Correlations: A Cross-Sectional Study Optical Coherence Tomography Combined with Fluorescein Fundus Angiography under Intelligent Algorithm to Evaluate the Clinical Efficacy of Ranibizumab Combined with Panretinal Photocoagulation in the Treatment of Macular Edema of Diabetic Retinopathy Pati Risk factors and characteristics of central serous chorioretinopathy with later development of macular neovascularisation detected on OCT angiography: a retrospective multicentre observational study