1. Articles from Laura Morales-Fernández

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    1. Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma

      Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma

      Objective: To evaluate the differences in peripapillary and macular vascular parameters by optical coherence tomography angiography (OCTA) between patients with primary congenital glaucoma (PCG) and healthy controls; and to determine their diagnostic accuracy. Material and methods: Observational, cross-sectional study including 39 eyes with PCG and 78 healthy eyes. Only one eye per patient was included. All included patients underwent a comprehensive ophthalmic examination and peripapillary and macular analysis were performed by Angioplex TM OCTA (Cirrus HD-OCT 5000) with a 4.5 × 4.5 mm optic nerve head scan and 6 × 6 mm macular scan. Global data and quadrant data from ...

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    2. Corneal Endothelial Cell Loss After PRESERFLO™ MicroShunt Implantation in the Anterior Chamber: Anterior Segment OCT Tube Location as a Risk Factor

      Corneal Endothelial Cell Loss After PRESERFLO™ MicroShunt Implantation in the Anterior Chamber: Anterior Segment OCT Tube Location as a Risk Factor

      Introduction: To analyze the effects of PRESERFLO on corneal endothelial cell density (ECD). Methods: Forty-six eyes that underwent PRESERFLO implantation were followed up for 12 months. Specular microscopy was performed preoperatively and at 1, 3, 6, and 12 months postoperatively to measure central ECD and mean monthly reduction (MMR). Anterior segment optical coherence tomography (AS-OCT) was applied to measure the tube-endothelium (TE < 200 μm, 201-500 μm, > 500 μm) distance. The relationship between TE distance and ECD was analyzed with a linear mixed-effects model. Results: Central ECD decreased significantly at 1 year (7.4%, p = 0.04), with an MMR of ...

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    3. Retinal and peripapillary vessel density increase in recovered COVID-19 children by optical coherence tomography angiography

      Retinal and peripapillary vessel density increase in recovered COVID-19 children by optical coherence tomography angiography

      Purpose To evaluate retinal vascular changes in children who have recovered from coronavirus disease (COVID-19) using optical coherence tomography angiography (OCTA) and to compare the results with age-matched healthy children. Methods In this cross-sectional case–control study, children 6-18 years of age with laboratory-confirmed SARS-CoV-2 infection were compared with historic healthy controls. All participants underwent ophthalmological examination, including fundus photography and OCTA of the macular region and optic disk. COVID-19 children were examined 4-8 weeks after COVID-19 diagnoses. Demographic data, medical history, and COVID-19 symptoms were noted. OCTA parameters in the superficial capillary plexus (SCP) were analyzed according to ETDRS ...

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    4. Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children

      Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children

      Aims : To evaluate the repeatability of the peripapillary and macular vascular parameters using optical coherence tomography angiography (OCT-A) in healthy children. Material and methods : Cross-sectional study including 34 eyes of 34 healthy children. After a complete medical examination, two consecutive OCT-A exams were done using AngioPlex Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA, USA) in the same session. The scan area used was 6x6 mm for the analysis of the superficial vascular plexus (SVP) in the macula, and 4.5x4.5 mm for the peripapillary plexus. To study the repeatability of the measurements, the intraclass correlation coefficient (ICC) and the ...

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    5. Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Purpose To compare the diagnostic performance of circumpapillary retinal nerve fiber layer (cpRNFL) analysis versus segmented ganglion cell complex analysis both by spectral-domain optical coherence tomography (SD-OCT) in children with primary congenital glaucoma (PCG). Methods Participants were 40 children diagnosed with PCG and 60 healthy children. Ophthalmological data collected (for one eye per child) were cup-disc ratio (C/D) and axial length (AL). SD-OCT with automated segmentation was used to measure the thicknesses and volumes of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL). For the cpRNFL measurements conventional S-D OCT software ...

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    6. Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Objective To examine differences in individual retinal layer thicknesses measured by spectral domain optical coherence tomography (SD-OCT) (Spectralis ® ) produced with age and according to sex. Design Cross-sectional, observational study. Methods The study was conducted in 297 eyes of 297 healthy subjects aged 18 to 87 years. In one randomly selected eye of each participant the volume and mean thicknesses of the different macular layers were measured by SD-OCT using the instrument's macular segmentation software. Main outcome measures Volume and mean thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer ...

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    7. Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Article Authors Metrics Comments Related Content Abstract Introduction Methods Results Discussion Supporting information Acknowledgments References Reader Comments (0) Media Coverage Figures Abstract Purpose Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). Methods On this transversal, observational study, 300 patients between 18 to 87 years old and without an ophthalmological condition were recruited. Macular OCT scans were performed on all patients (Spectralis OCT, Heidelberg Engineering). An axial length measurement, and keratometry were performed using an ...

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    8. Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles

      Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles

      Purpose To determine the distance of the horizontal rectus muscle insertion to the limbus using spectral domain optical coherence tomography (SD-OCT) and to evaluate whether results are correlated with sex, age, or axial length. Methods The right eyes of healthy, white subjects were imaged with SD-OCT. Subjects’ sex and age were recorded, and axial length was measured using an optical biometer. The distance from the horizontal rectus insertion to the limbus was measured. The intraclass correlation coefficient (ICC) was used to assess the reproducibility of the measurements with a subset of images. A multivariate model was adjusted to analyze whether ...

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    1-8 of 8
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    Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children Retinal and peripapillary vessel density increase in recovered COVID-19 children by optical coherence tomography angiography Corneal Endothelial Cell Loss After PRESERFLO™ MicroShunt Implantation in the Anterior Chamber: Anterior Segment OCT Tube Location as a Risk Factor Peripapillary and macular vascular parameters by optical coherence tomography angiography in primary congenital glaucoma Comparison of Anterior Segment Measurements with a New Multifunctional Unit and Five Other Devices Efficacy of Notal Vision Home OCT demonstrated by a series of scientific and clinical work Synergy Between morpHOlogical and inflammatoRy Evaluation in Predicting Long-term Coronary Plaque Progression Altered ocular microvasculature in patients with systemic sclerosis and very early disease of systemic sclerosis using optical coherence tomography angiography