1. Articles from Paula Antuña

    1-11 of 11
    1. Diagnosis of Intraplaque Hemorrhage by High-Definition Intravascular Ultrasound and Optical Coherence Tomography

      Diagnosis of Intraplaque Hemorrhage by High-Definition Intravascular Ultrasound and Optical Coherence Tomography

      A 67-year-old woman, a heavy smoker and with hypothyroidism, presented with a non–STsegment elevation myocardial infarction with negative T waves on the inferior leads. Coronary angiography revealed a focal stenosis in the mid right coronary artery (arrow in Figure 1A) but no other coronary lesions. High-definition (60-MHz) intravascular ultrasound (IVUS) (ACIST Medical Systems, Eden Prairie, Minnesota) revealed a large hyperechoic noncalcific plaque encompassing a well-delineated, crescent-shaped area showing a striking hypoechogenicity (echolucent “black” area) (yellow asterisks in Figures 1B and 1C [white asterisk denotes wire artifact]). The immediately adjacent plaque had a more reflective pattern with marked speckling (Figures ...

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    2. Severe coronary spasm in a COVID‐19 patient

      Severe coronary spasm in a COVID‐19 patient

      Myocardial injury is frequently detected in coronavirus disease 2019 (COVID‐19) patients. However, up to one‐third of COVID‐19 patients showing ST‐segment elevation on the electrocardiogram have angiographically normal coronary arteries. We present a case of an acute coronary syndrome due to a coronary spasm in a severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) patient. This pathophysiological mechanism was clearly demonstrated by intracoronary imaging techniques (optical coherence tomography) and invasive vasospasm test.

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      Mentions: Fernando Alfonso
    3. Very late stent thrombosis of a titanium-nitride-oxide-coated bioactive stent resulting from neoatherosclerosis: Optical coherence tomography insights

      Very late stent thrombosis of a titanium-nitride-oxide-coated bioactive stent resulting from neoatherosclerosis: Optical coherence tomography insights

      This is the first reported case of a BAS very late stent thrombosis resulting from ruptured neoatherosclerosis. • Optical Coherence Tomography provides unique insight to unravel the presence of neoatherosclerosis. • Very late stent thrombosis of BAS resulting from neoatherosclerosis is an uncommon but feared complication.

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    4. Role of optical coherence tomography for distal left main stem angioplasty

      Role of optical coherence tomography for distal left main stem angioplasty

      Objective The objective is to analyze the acute and midterm angiographic outcome of percutaneous treatment of left main coronary stem (LM‐PCI) guided by optical coherence tomography (OCT). Background LM‐PCI is a complex procedure, and several anatomical factors may impair its outcome. Intravascular imaging is emerging as a useful tool to guide the procedure. Methods We conducted a retrospective analysis of patients undergoing LM‐PCI at three European centers between 2014 and 2017 with a control angiography at 6–12 months. Patients were divided into two groups: OCT‐guidance (pre‐ and post‐PCI) and control group (standard angiographic guidance ...

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    5. Calcified neoatherosclerosis causing in-stent restenosis: prevalence, predictors, and implications

      Calcified neoatherosclerosis causing in-stent restenosis: prevalence, predictors, and implications

      Background Neoatherosclerosis has emerged as a major cause of in-stent restenosis (ISR). Although this entity has been described as a unique process, optical coherence tomography (OCT) enables depiction of distinct morphologic patterns, including the presence of calcified sheets within the stent. We sought to assess prevalence, predictors, and implications of calcified neoatherosclerosis (cNA) as the cause of ISR. Methods and results From January 2014 to August 2016, 75 consecutive patients with 81 ISR lesions with a clinical indication for revascularization were evaluated by OCT before reintervention. In 13 (16%) lesions, cNA was the predominant pattern of ISR, all of them ...

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      Mentions: Fernando Alfonso
    6. Early restenosis of resorbable magnesium scaffolds: Optical coherence tomography findings

      Early restenosis of resorbable magnesium scaffolds: Optical coherence tomography findings

      Resorbable Magnesium Scaffolds (RMS) represent an interesting alternative to current drug‐eluting stents. Current data from clinical trials seems to confirm good performance of these new devices with low rates of late device failure. Little is known about mechanisms leading to RMS failure. Herein, we present the first description of an early RMS in‐scaffold restenosis. Optical coherence tomography (OCT) analysis at implantation detected acute non‐severe malapposition and underexpansion as main promoters of RMS failure. OCT during in‐scaffold restenosis intervention confirmed early severe neointimal proliferation and RMS late recoil and dismantling as the main mechanisms of device failure ...

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      Mentions: Fernando Alfonso
    7. Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Introduction Straightening of tortuous coronaries by intracoronary guidewires may generate intimal wrinkles or coronary pleating and lead to the development of different abnormal angiographic findings widely known as pseudostenosis or accordion effect. 1 We report the unique findings disclosed by optical coherence tomography (OCT) in 3 patients developing coronary pleating. Patient 1 An 84-year-old woman with severe aortic stenosis was referred for coronary angiography before transcatheter aortic valve implantation. A severe stenosis in the mid segment of the right coronary artery was treated with a bare metal stent. The guidewire induced a new moderate focal lesion at the most proximal ...

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      Mentions: Fernando Alfonso
    8. Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Introduction Straightening of tortuous coronaries by intracoronary guidewires may generate intimal wrinkles or coronary pleating and lead to the development of different abnormal angiographic findings widely known as pseudostenosis or accordion effect. We report the unique findings disclosed by optical coherence tomography (OCT) in 3 patients developing coronary pleating. Patient 1 An 84-year-old woman with severe aortic stenosis was referred for coronary angiography before transcatheter aortic valve implantation. A severe stenosis in the mid segment of the right coronary artery was treated with a bare metal stent. The guidewire induced a new moderate focal lesion at the most proximal segment ...

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      Mentions: Fernando Alfonso
    1-11 of 11
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  2. Topics in the News

    1. (9 articles) Fernando Alfonso
    2. (2 articles) Francesco Prati
    3. (1 articles) Academic Medical Center at the University of Amsterdam
    4. (1 articles) Jichi Medical University
    5. (1 articles) University of Milan
    6. (1 articles) Bern University Hospital
    7. (1 articles) Capital Medical University
    8. (1 articles) Nanjing University of Science and Technology
    9. (1 articles) Martin S. Zinkernagel
    10. (1 articles) Junya Ako
    11. (1 articles) Frank D. Verbraak
    12. (1 articles) Giovanni Staurenghi
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    Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography Bioresorbable Vascular Scaffold Thrombosis: Clinical and Optical Coherence Tomography Findings Early restenosis of resorbable magnesium scaffolds: Optical coherence tomography findings Calcified neoatherosclerosis causing in-stent restenosis: prevalence, predictors, and implications Role of optical coherence tomography for distal left main stem angioplasty Value of Optical Coherence Tomography in Angiographically Intermediate Coronary Lesions Holistic treatment of heavily calcified coronary lesions Lithoplasty guidance by optical coherence tomography Very late stent thrombosis of a titanium-nitride-oxide-coated bioactive stent resulting from neoatherosclerosis: Optical coherence tomography insights Diagnosis of Intraplaque Hemorrhage by High-Definition Intravascular Ultrasound and Optical Coherence Tomography Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections