1. Articles from Joseph Ho

    1-6 of 6
    1. AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY

      AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To assess the agreement and reproducibility of retinal pigment epithelial detachment (RPED) volumetric measurements using a commercially available optical coherence tomography software available for the Zeiss Cirrus HD-OCT. Methods: Twelve eyes of 10 patients with a diagnosis of neovascular age-related macular degeneration with RPED, seen at the New England Eye Center between October 2012 and December 2012, were enrolled in the study. Three separate scans per affected eye were obtained using the "Macular Cube 512 x 128" protocol. "Retinal pigment epithelial (RPE) elevation analysis" software was used to measure RPED volumes in the central 3-mm and 5-mm circles by ...

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    2. Analysis of Normal Peripapillary Choroidal Thickness via Spectral Domain Optical Coherence Tomography

      Analysis of Normal Peripapillary Choroidal Thickness via Spectral Domain Optical Coherence Tomography
      Purpose To analyze the normal peripapillary choroidal thickness utilizing a commercial spectral domain optical coherence tomography (OCT) device and determine the intergrader reproducibility of this method. Design Retrospective, noncomparative, noninterventional case series. Participants Thirty-six eyes of 36 normal patients seen at the New England Eye Center between April and September 2010. Methods All patients underwent high-definition scanning with the Cirrus HD-OCT. Two raster scans were obtained per eye, a horizontal and a vertical scan, both of which were centered at the optic nerve. Two independent graders individually measured the choroidal thickness. Choroidal thickness was measured from the posterior edge of ...
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    3. Documentation of Intraretinal Retinal Pigment Epithelium Migration via High-Speed Ultrahigh-Resolution Optical Coherence Tomography

      Documentation of Intraretinal Retinal Pigment Epithelium Migration via High-Speed Ultrahigh-Resolution Optical Coherence Tomography

      Purpose: To describe the features of intraretinal retinal pigment epithelium (RPE) migration documented on a prototype spectral-domain, high-speed, ultrahigh-resolution optical coherence tomography (OCT) device in a group of patients with early to intermediate dry age-related macular degeneration (AMD) and to correlate intraretinal RPE migration on OCT to RPE pigment clumping on fundus photographs. Design: Retrospective, noncomparative, noninterventional case series. Participants: Fifty-five eyes of 44 patients seen at the New England Eye Center between December 2007 and June 2008 with early to intermediate dry AMD. Methods: Three-dimensional OCT scan sets from all patients were analyzed for the presence of intraretinal RPE ...

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    4. Clinical Assessment of Mirror Artifacts in Spectral Domain Optical Coherence Tomography

      Clinical Assessment of Mirror Artifacts in Spectral Domain Optical Coherence Tomography
      Purpose: To investigate the characteristics of a spectral domain Optical Coherence Tomography (SD OCT) image artifact known as the "mirror artifact", calculate its prevalence, analyze potential risk factors, measure severity, and correlate it to spherical equivalent and central visual acuity (VA). Methods: Cirrus HD-OCT Macular Cube 512x128 scans taken between January 2008 and February 2009 at the New England Eye Center were analyzed for the presence of mirror artifacts. Artifact severity was analyzed by the degree of segmentation breakdown that it causes on the macular map. A retrospective medical records review was conducted for patients with artifacts and for a ...
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    5. Assessment of Artifacts and Reproducibility across Spectral- and Time-Domain Optical Coherence Tomography Devices

      Purpose: To report the frequency of optical coherence tomography (OCT) scan artifacts and to compare macular thickness measurements, interscan reproducibility, and interdevice agreeability across 3 spectral-domain (SD) OCT (also known as Fourier domain; Cirrus HD-OCT, RTVue-100, and Topcon 3D-OCT 1000) devices and 1 time-domain (TD) OCT (Stratus OCT) device.Design: Prospective, noncomparative, noninterventional case series.Participants: Fifty-two patients seen at the New England Eye Center, Tufts Medical Center Retina Service, between February and August 2008.Methods: Two scans were performed for each of the SD OCT protocols: Cirrus macular cube 512×128 (software version 3.0; Carl Zeiss Meditec, Inc ...
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    6. Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration

      Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration

      Ultrahigh resolution optical coherence tomography (OCT) enhances the ability to visualize different intra retinal layers. In age-related macular degeneration (AMD), pathological changes in individual retinal layers, including photoreceptor inner and outer segments and retinal pigment ... [Opt. Express 17, 4046-4060 (2009)]

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    1-6 of 6
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    1. (6 articles) Tufts University
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    Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration Clinical Assessment of Mirror Artifacts in Spectral Domain Optical Coherence Tomography Documentation of Intraretinal Retinal Pigment Epithelium Migration via High-Speed Ultrahigh-Resolution Optical Coherence Tomography Analysis of Normal Peripapillary Choroidal Thickness via Spectral Domain Optical Coherence Tomography AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY Cooperative low-rank models for removing stripe noise from OCTA images MS-CAM: Multi-Scale Class Activation Maps for Weakly-supervised Segmentation of Geographic Atrophy Lesions in SD-OCT Images Attention-guided 3D-CNN Framework for Glaucoma Detection and Structural-Functional Association using Volumetric Images Machine Learning Techniques for Ophthalmic Data Processing: A Review Dynamic Imaging of Mouse Embryos and Cardiac Development in Static Culture Effects of axial length on retinal nerve fiber layer and macular ganglion cell-inner plexiform layer measured by spectral-domain OCT Innovative method offers a new way of studying developmental cardiac biomechanics, live in 4-D