1. Articles from Marieh Esmaeelpour

    1-11 of 11
    1. Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography

      Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography

      Purpose : To analyze retinal thickness (RT) and choroidal thickness (ChT) changes in patients with unilateral nongranulomatous acute anterior uveitis (AAU) using three-dimensional (3D) 1060-nm optical coherence tomography (OCT). Methods : Retinal and choroidal thickness maps were statistically analyzed for 24 patients with newly diagnosed unilateral AAU before therapy. A total of 17 patients were followed until resolution of inflammatory activity (twice in the first week, then weekly). Resolution occurred in all subjects within 6 weeks after the initial diagnosis. After resolution, thickness maps were again generated. All patients were imaged by high-speed spectral-domain (SD) 3D 1060-nm OCT over a 10 × 10-mm ...

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    2. Mapping diurnal changes in choroidal, Haller’s and Sattler’s layer thickness using 3-dimensional 1060-nm optical coherence tomography

      Mapping diurnal changes in choroidal, Haller’s and Sattler’s layer thickness using 3-dimensional 1060-nm optical coherence tomography

      Purpose To test the significance of diurnal changes in choroidal, Haller’s and Sattler’s layer thickness in healthy subjects using spatial analysis of three-dimensional (3D) 1060-nm optical coherence tomography (OCT) scans. Methods Automatically generated choroidal, Haller’s and Sattler’s layer thickness maps were statistically analyzed for 19 healthy subjects at two time points (8 a.m. and 6 p.m.) that represent the currently proposed ChT peak and nadir. All subjects were imaged by high-speed 1060-nm OCT over a 36° × 36° field of view. Spatial distribution of layer thickness was analyzed using the Early Treatment Diabetic Retinopathy Study ...

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    3. Choroidal Haller's and Sattler's Layer Thickness Measurement Using 3-Dimensional 1060-nm Optical Coherence Tomography

      Choroidal Haller's and Sattler's Layer Thickness Measurement Using 3-Dimensional 1060-nm Optical Coherence Tomography

      Objectives To examine the feasibility of automatically segmented choroidal vessels in three-dimensional (3D) 1060-nmOCT by testing repeatability in healthy and AMD eyes and by mapping Haller's and Sattler's layer thickness in healthy eyes Methods Fifty-five eyes (from 45 healthy subjects and 10 with non-neovascular age-related macular degeneration (AMD) subjects) were imaged by 3D-1060-nmOCT over a 36°x36° field of view. Haller's and Sattler's layer were automatically segmented, mapped and averaged across the Early Treatment Diabetic Retinopathy Study grid. For ten AMD eyes and ten healthy eyes, imaging was repeated within the same session and on another ...

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    4. Choroidal thickness in patients with reticular pseudodrusen using 3D-1060nm OCT maps

      Choroidal thickness in patients with reticular pseudodrusen using 3D-1060nm OCT maps

      Purpose: To map and analyze choroidal thickness (ChT) in age-related macular degeneration patients with reticular pseudodrusen (RPD) using 3-dimensional (3D) 1060nm optical coherence tomography (OCT). Methods: Fifty eyes from twenty-five patients with RPD were grouped according to the severity of age-related macular degeneration (AMD) and the presence of RPD. All patients were imaged by high speed (60.000 A-scans/s) 3D-1060nm OCT over a 36x36° field of view. ChT-maps were automatically generated and compared to RPD areas visualized by fundus autofluorescence and infra-red imaging. Retinal thickness maps, ChT maps, Haller's and Sattler's layer thickness were statistically analyzed between ...

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    5. Choroidal Thinning in Diabetes Type 1 Detected by 3-Dimensional 1060 nm Optical Coherence Tomography

      Choroidal Thinning in Diabetes Type 1 Detected by 3-Dimensional 1060 nm Optical Coherence Tomography
      Purpose. To map choroidal (ChT) and retinal thickness (RT) in patients with diabetes type 1 with and without maculopathy and retinopathy in order to compare them with healthy subjects using high speed 3-dimensional (3D) 1060 nm optical coherence tomography (OCT). Methods. Thirty-three eyes from 33 diabetes type 1 subjects (23–57 years, 15 male) divided into groups of without pathology (NDR) and with pathology (DR; including microaneurysms, exudates, clinically significant macular-oedema and proliferative retinopathy) were compared with 20 healthy axial eye length and age-matched subjects (24–57 years, 9 male), imaged by high speed (60.000 A-scans/s) 3D 1060 ...
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    6. Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model

      Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model
      A two stage statistical model based on texture and shape for fully automatic choroidal segmentation of normal and pathologic eyes obtained by a 1060 nm optical coherence tomography (OCT) system is developed. A novel dynamic programming approach is implemented to determine location of the retinal pigment epithelium/ Bruch’s membrane /choriocapillaris (RBC) boundary. The choroid–sclera interface (CSI) is segmented using a statistical model. The algorithm is robust even in presence of speckle noise, low signal (thick choroid), retinal pigment epithelium (RPE) detachments and atrophy, drusen, shadowing and other artifacts. Evaluation against a set of 871 manually segmented cross-sectional scans ...
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    7. Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration

      Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration
      Purpose To compare retinal thickness and choroidal thickness at increasing retinal eccentricity in individuals with early age-related macular degeneration (AMD) and in healthy controls using enhanced choroidal penetration, 3-dimensional optical coherence tomography at 1060 nm. Design Cross-sectional study. Methods Individuals with early AMD (n = 16; mean age, 71.6 ± 8.5 years) and a comparison group of healthy controls (n = 16; 67.6 ± 5.4 years) were recruited. Three-dimensional (20 degrees × 20 degrees) long-wavelength optical coherence tomography (1060 nm) images (approximately 8-μm axial resolution; 47 000 A scans/second, centered on the fovea) were obtained from all participants after pupil ...
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    8. Mapping Choroidal and Retinal Thickness Variation in Type 2 Diabetes using Three-Dimensional 1060-nm Optical Coherence Tomography

      Mapping Choroidal and Retinal Thickness Variation in Type 2 Diabetes using Three-Dimensional 1060-nm Optical Coherence Tomography
      Purpose. To map choroidal (ChT) and retinal thickness (RT) in healthy subjects and patients with diabetes with and without maculopathy using three dimensional 1060-nm optical coherence tomography (3D-1060nm-OCT). Methods. Sixty-three eyes from 42 diabetic subjects (41–82 years of age; 11 females) grouped according to a custom scheme using Early Treatment Diabetic Retinopathy Study definitions for pathology within 1 disc-diameter of fovea (without pathology [NDR], microaneurysms [M1], exudates [M2], clinically significant macular edema [CSME]) and 16 eyes from 16 healthy age matched subjects (38–79 years of age; 11 females) were imaged by 3D-1060nm-OCT performed over a 36° × 36° field ...
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    9. Three-Dimensional 1060-nm OCT: Choroidal Thickness Maps in Normal Subjects and Improved Posterior Segment Visualization in Cataract Patients

      Three-Dimensional 1060-nm OCT: Choroidal Thickness Maps in Normal Subjects and Improved Posterior Segment Visualization in Cataract Patients
      Purpose. To evaluate the performance and potential clinical role of three-dimensional (3D) 1060-nm OCT by generating choroidal thickness (ChT) maps in patients of different ages with different degrees of ametropia and axial lengths and to investigate the effect of cataract grade on OCT retinal imaging quality. Methods. Axial lengths (ALs) and 45° fundus photographs were acquired from 64 eyes (34 healthy subjects, 19 to 80 years, ametropia +3 to –10 D). 3D 1060-nm OCT was performed over a 36° x 36° field of view with 7-µm axial resolution and up to 70 frames/s (512 A-scans/frame). ChT maps between ...
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    10. Three-dimensional 1060nm OCT: Choroidal thickness maps in normals and improved posterior segment visualization in cataract patients

      Three-dimensional 1060nm OCT: Choroidal thickness maps in normals and improved posterior segment visualization in cataract patients
      Purpose. To evaluate the performance and potential clinical role of 3D-1060nm-OCT by generating choroidal thickness (ChT) maps in patients of different age, ametropia and axial lengths and to investigate the effect of cataract grade on OCT retinal imaging quality. Methods. Axial lengths (AL) and 45° fundus photographs were acquired from 64 eyes (34 healthy subjects, 19-80 years, ametropia +3 to -10D). 3D-1060nm-OCT was performed over 36°x36° field of view with ~7µm axial resolution and up to 70 frames/second (512 A-scans/frame). ChT-maps between retinal pigment epithelium and the choroidal/scleral-interface, were generated and statistically analyzed. A further thirty ...
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    11. Impact of enhanced resolution, speed and penetration on three-dimensional retinal optical coherence tomography

      Impact of enhanced resolution, speed and penetration on three-dimensional retinal optical coherence tomography
      Recent substantial developments in light source and detector technology have initiated a paradigm shift in retinal optical coherence tomography (OCT) performance. Broad bandwidth light sources in the 800 nm and 1060 nm wavelength region enable axial OCT resolutions of 2-3 μm and 5-7 ... [Opt. Express 17, 4134-4150 (2009)]
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    1-11 of 11
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  2. Topics in the News

    1. (11 articles) Marieh Esmaeelpour
    2. (11 articles) Wolfgang Drexler
    3. (10 articles) Medical University of Vienna
    4. (7 articles) Boris Považay
    5. (6 articles) Cardiff University
    6. (6 articles) Boris Hermann
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    Impact of enhanced resolution, speed and penetration on three-dimensional retinal optical coherence tomography Three-dimensional 1060nm OCT: Choroidal thickness maps in normals and improved posterior segment visualization in cataract patients Three-Dimensional 1060-nm OCT: Choroidal Thickness Maps in Normal Subjects and Improved Posterior Segment Visualization in Cataract Patients Mapping Choroidal and Retinal Thickness Variation in Type 2 Diabetes using Three-Dimensional 1060-nm Optical Coherence Tomography Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model Choroidal Thinning in Diabetes Type 1 Detected by 3-Dimensional 1060 nm Optical Coherence Tomography Choroidal thickness in patients with reticular pseudodrusen using 3D-1060nm OCT maps Choroidal Haller's and Sattler's Layer Thickness Measurement Using 3-Dimensional 1060-nm Optical Coherence Tomography Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography Evaluation of Age-related Skin Changes and Instrument Reliability Using Clinical Probe Measurements and Imaging Modalities HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award