1. Articles from Chris P. Lohmann

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    1. Repeatability and Reproducibility of Macular Hole Size Measurements Using Optical Coherence Tomography

      Repeatability and Reproducibility of Macular Hole Size Measurements Using Optical Coherence Tomography

      The purpose of this study was to assess the repeatability and reproducibility of measuring the minimum linear diameter (MLD) of macular holes (MHs) using horizontal linear and radial scan modes in optical coherence tomography (OCT). Patients with concurrent sets of radial and horizontal linear OCT volume scans were included. The MLD was measured twice in both scan modes by six raters of three different experience levels (groups). Outcome measures were the reliability and repeatability of MLD measurements. Fifty patients were included. Mean MLD was 317.21(±170.63) µm in horizontal linear and 364.52 (±161.71) µm in radial ...

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    2. Functional recovery after macula involving retinal detachment and its correlation with preoperative biomarkers in optical coherence tomography

      Functional recovery after macula involving retinal detachment and its correlation with preoperative biomarkers in optical coherence tomography

      To introduce an ETDRS grid-based classification for macula involving retinal detachment (MIRD) with or without center (foveal) involvement and to identify biomarkers in preoperative optical coherence tomography (OCT) associated with a favorable postoperative functional outcome in eyes with center involving retinal detachment (CIRD). One hundred and two eyes of 102 consecutive patients (f/m: 35/67) with primary rhegmatogenous retinal detachment, preoperative evidence of MIRD (perifoveal involvement of ≤ 6.0 mm), and successful retinal surgery were included in this retrospective cohort study. Eyes were assigned to 5 grades of MIRD (G1-G5), based on the extent of detachment in the ETDRS ...

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    3. Choriocapillaris Flow Density Negatively Correlates With Advancing Age on Spectral-Domain Optical Coherence Tomography Angiography

      Choriocapillaris Flow Density Negatively Correlates With Advancing Age on Spectral-Domain Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To correlate subfoveal choriocapillaris (CC) flow density with age using spectral-domain optical coherence tomography angiography (SD-OCTA). PATIENTS AND METHODS: One hundred eighty-three eyes of 94 subjects (66 female, 28 male) were enrolled. Included were healthy subjects between the ages of 21 and 82 years without any history of vitreoretinal disease. Measurements were obtained with software from the OCT device. Significance was defined as a P value of less than .05. RESULTS: The mean age was 43.43 years ± 17.63 years. Correlation between decreasing CC flow density and increasing age was significant ( P < .001), with a mean ...

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    4. Choriocapillary Blood Flow in Myopic Subjects Measured With OCT Angiography

      Choriocapillary Blood Flow in Myopic Subjects Measured With OCT Angiography

      BACKGROUND AND OBJECTIVE: To investigate choriocapillary blood flow in myopic eyes using optical coherence tomography angiography. PATIENTS AND METHODS: Seventy-eight myopic and 79 age-matched healthy eyes were included in this study, with myopia defined as a spherical equivalent refraction (SER) between −1 diopters (D) and −6 D. Quantitative measurements of the choriocapillaris were obtained using the Avanti RTVue XR with AngioVue. Choroidal thickness (CT) was assessed using the single-line enhanced high-definition scan of the same device. RESULTS: CT correlated positively with SER ( P = .017) and negatively with bulbus axial length (AL) ( P = .180). Subfoveal choriocapillary blood flow did not show ...

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    5. Towards Robotic Eye Surgery: Marker-free, Online Hand-eye Calibration using Optical Coherence Tomography Images

      Towards Robotic Eye Surgery: Marker-free, Online Hand-eye Calibration using Optical Coherence Tomography Images

      Ophthalmic microsurgery is known to be a challenging operation, which requires very precise and dexterous manipulation. Image guided robot-assisted surgery (RAS) is a promising solution that brings significant improvements in outcomes and reduces the physical limitations of human surgeons. However, this technology must be further developed before it can be routinely used in clinics. One of the problems is the lack of proper calibration between the robotic manipulator and appropriate imaging device. In this work, we developed a flexible framework for hand-eye calibration of an ophthalmic robot with a microscope-integrated Optical Coherence Tomography (MI-OCT) without any markers. The proposed method ...

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    6. Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery

      Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery

      Needle segmentation is a fundamental step for needle reconstruction and image-guided surgery. Although there has been success stories in needle segmentation for non-microsurgeries, the methods cannot be directly extended to ophthalmic surgery due to the challenges bounded to required spatial resolution. As the ophthalmic surgery is performed by finer and smaller surgical instruments in micro-structural anatomies, specifically in retinal domains, difficulties are raised for delicate operation and sensitive perception. To address these challenges, in this paper we investigate needle segmentation in ophthalmic operation on 60 Optical Coherence Tomography (OCT) cubes captured during needle injection surgeries on ex-vivo pig eyes. Furthermore ...

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    7. OCT Angiography Findings in Acute Central Serous Chorioretinopathy

      OCT Angiography Findings in Acute Central Serous Chorioretinopathy

      BACKGROUND AND OBJECTIVE: To describe optical coherence tomography angiography (OCTA) findings in patients with acute central serous chorioretinopathy (CSC) compared to conventional imaging methods. PATIENTS AND METHODS: A consecutive series of 11 eyes from 10 healthy patients with acute CSC were included and underwent fluorescein angiography (FA), indocyanine green angiography (ICGA), OCT, fundus autofluorescence (FAF), and OCTA. Obtained OCTA images were evaluated for the presence of serous detachments of the neurosensory retina, leakage points, or other altered findings and compared to conventional imaging devices. RESULTS: In four out of 11 eyes, it was possible to detect detached retina adjacent to ...

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    1-7 of 7
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    OCT Angiography Findings in Acute Central Serous Chorioretinopathy Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery Towards Robotic Eye Surgery: Marker-free, Online Hand-eye Calibration using Optical Coherence Tomography Images Choriocapillary Blood Flow in Myopic Subjects Measured With OCT Angiography Choriocapillaris Flow Density Negatively Correlates With Advancing Age on Spectral-Domain Optical Coherence Tomography Angiography Functional recovery after macula involving retinal detachment and its correlation with preoperative biomarkers in optical coherence tomography Repeatability and Reproducibility of Macular Hole Size Measurements Using Optical Coherence Tomography Structural abnormalities associated with glaucoma using swept-source optical coherence tomography in patients with systemic sclerosis Clinical presentation does not affect acute mechanical performance of the Novolimus-eluting bioresorbable vascular scaffold as assessed by optical coherence tomography Evaluating optical coherence tomography (OCT) findings as potential biomarkers in central nervous system (CNS) lymphoma with or without ocular involvement Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations Etanercept Therapy for Nails Psoriasis Monitoring With Noninvasive Imaging