1. Articles from Phil-Sang Chung

    1-4 of 4
    1. Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis

      Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis

      Subglottic stenosis (SGS) is a challenging disease to diagnose in neonates. Long-range optical coherence tomography (OCT) is an optical imaging modality that has been described to image the subglottis in intubated neonates. A major challenge associated with OCT imaging is the lack of an automated method for image analysis and micrometry of large volumes of data that are acquired with each airway scan (1 to 2 Gb). We developed a tissue segmentation algorithm that identifies, measures, and conducts image analysis on tissue layers within the mucosa and submucosa and compared these automated tissue measurements with manual tracings. We noted small ...

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    2. Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging

      Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging

      While colonoscopy is the gold standard for diagnosis and classification of colorectal cancer (CRC), its sensitivity and specificity are operator-dependent and are especially poor for small and flat lesions. Contemporary imaging modalities, such as optical coherence tomography (OCT) and near-infrared (NIR) fluorescence, have been investigated to visualize microvasculature and morphological changes for detecting early stage CRC in the gastrointestinal (GI) tract. In our study, we developed a multimodal endoscopic system with simultaneous co-registered OCT and NIR fluorescence imaging. By introducing a contrast agent into the vascular network, NIR fluorescence is able to highlight the cancer-suspected area based on significant change ...

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    3. In vivo monitoring laser tissue interaction using high resolution Fourier-domain optical coherence tomography

      In vivo monitoring laser tissue interaction using high resolution Fourier-domain optical coherence tomography

      Laser-induced therapies include laser ablation to remove or cut target tissue by irradiating high-power focused laser beam. These laser treatments are widely used tools for minimally invasive surgery and retinal surgical procedures in clinical settings. In this study, we demonstrate laser tissue interaction images of various sample tissues using high resolution Fourier-domain optical coherence tomography (Fd-OCT). We use a Q-switch diode-pumped Nd:YVO4 nanosecond laser (532nm central wavelength) with a 4W maximum output power at a 20 kHz repetition rate to ablate in vitro and in vivo samples including chicken breast and mouse ear tissues. The Fd-OCT system acquires time-series ...

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      Mentions: Dae Yu Kim
    4. Development of 2-micron nonlinear frequency conversion laser system and tissue interaction monitoring using optical coherence tomography

      Development of 2-micron nonlinear frequency conversion laser system and tissue interaction monitoring using optical coherence tomography

      We report on development of optical parametric oscillator (OPO) based mid-infrared laser system, which utilizes periodically poled nonlinear crystal that was pumped by near-infrared (NIR) laser. We have obtained 8 W of mid-infrared average output at the injection current of 20A from a quasi-phase-matched OPO using external cavity configuration. The laser tissue ablation efficiency was investigated which is substantially affected by several parameters such as, optical fluence rate, wavelength of the laser source and the optical properties of target tissue. Wavelength and radiant exposure dependent tissue ablation dimension were quantified by using SD-OCT (spectral domain optical coherence tomography) and the ...

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      Mentions: Dae Yu Kim
    1-4 of 4
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  2. Topics in the News

    1. (2 articles) UC Irvine
    2. (2 articles) Dae Yu Kim
    3. (2 articles) Zhongping Chen
    4. (1 articles) Yan Li
    5. (1 articles) Brian J. F. Wong
    6. (1 articles) Joseph C. Jing
    7. (1 articles) Medical University of Vienna
    8. (1 articles) Harbin Medical University
    9. (1 articles) Université Pierre et Marie Curie
    10. (1 articles) University of Erlangen
    11. (1 articles) Wolfgang Drexler
    12. (1 articles) Adrian G. Podoleanu
    13. (1 articles) Mengyang Liu
    14. (1 articles) Bo Yu
    15. (1 articles) Rainer A. Leitgeb
    16. (1 articles) Angelika Unterhuber
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    Development of 2-micron nonlinear frequency conversion laser system and tissue interaction monitoring using optical coherence tomography In vivo monitoring laser tissue interaction using high resolution Fourier-domain optical coherence tomography Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging Dynamic programming and automated segmentation of optical coherence tomography images of the neonatal subglottis: enabling efficient diagnostics to manage subglottic stenosis Changes in the Retinal Microvasculature Measured Using Optical Coherence Tomography Angiography According to Age Direct en-face, speckle-reduced images using angular-compounded Master-Slave optical coherence tomography A case report of a recurrent early and late Bioresorbable vascular scaffold thrombosis: serial angiography and optical coherence tomography findings Optical coherence tomography angiography as a novel approach to contactless evaluation of sublingual microcirculation: A proof of principle study Functional optical coherence tomography and photoacoustic microscopy imaging for zebrafish larvae Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography Retinal neurodegeneration in patients with end-stage renal disease assessed by spectral-domain optical coherence tomography Swept-source optical coherence tomography by off-axis Fresnel transform digital holography with an output throughput of 10 Giga voxels per second in real-time