1. Articles from Roger Lewis

    1-4 of 4
    1. Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography

      Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography

      Background Changes in body posture cause changes in morphological properties at different skin sites. Although previous studies have reported the thickness of the skin, the details of the postures are not generally given. This paper presents the effect of a change in posture on parameters such as thickness and surface roughness in 21 load-bearing and non-load-bearing sites. Materials and methods A total of 12 volunteers (8 males and 4 females) were selected in an age group of 18–35 years and of Fitzpatrick skin type I-III. Images were captured using a clinically-approved VivoSight® optical coherence tomography system and analysed using ...

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    2. Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography

      Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography

      Measurement of sub-clinical atopic dermatitis (AD) is important for determining how long therapies should be continued after clinical clearance of visible AD lesions. An important biomarker of subclinical AD is epidermal hypertrophy, the structural measures of which often make optical coherence tomography (OCT) challenging due to the lack of a clearly delineated dermal-epidermal junction in AD patients. Alternatively, angiographic OCT measurements of vascular depth and morphology may represent a robust biomarker for quantifying the severity of clinical and sub clinical AD. To investigate this, angiographic data sets were acquired from 32 patients with a range of AD severities. Deeper vascular ...

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    3. In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching

      In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching

      Stratum corneum and epidermal layers change in terms of thickness and roughness with gender, age and anatomical site. Knowledge of the mechanical and tribological properties of skin associated with these structural changes are needed to aid in the design of exoskeletons, prostheses, orthotics, body mounted sensors used for kinematics measurements and in optimum use of wearable on-body devices. In this case study, optical coherence tomography (OCT) and digital image correlation (DIC) were combined to determine skin surface strain and sub-surface deformation behaviour of the volar forearm due to natural tissue stretching. The thickness of the epidermis together with geometry changes ...

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    4. Optical coherence elastography for human finger-pad skin deformation studies

      Optical coherence elastography for human finger-pad skin deformation studies

      An optical coherence tomography (OCT) system with an A-scan rate of 20 kHz was developed for measuring the biomechanical properties of human finger-pad skin. Such an OCT system operates at a center wavelength of 890 nm with a spectral bandwidth of 150 nm resulting in a very good axial resolution of 2.6 μm. The measured sensitivity and sensitivity roll-off of the system were ~93 dB and ~6 dB mm -1 , respectively. Elastographic B-scan images of the human finger-pad skin were constructed by using 1000 A-scans. Deformations of the human finger-pad before and after sliding, while pressed against a transparent ...

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    1-4 of 4
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    1. (4 articles) University of Sheffield
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    Optical coherence elastography for human finger-pad skin deformation studies In vivo measurement of skin surface strain and sub-surface layer deformation induced by natural tissue stretching Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study GaAs-Based InPBi Quantum Dots for High Efficiency Super-Luminescence Diodes Pearls and Pitfalls of Optical Coherence Tomography Angiography Image Interpretation Novel optical coherence tomography findings in idiopathic choroidal folds Artificial Intelligence and Healthcare: Products and Procedures Oral Diagnosis Minimally Invasive Imaging Approaches (Textbook) Machine learning, imaging technique may boost colon cancer diagnosis Choroidal thickness and the retinal ganglion cell complex in chronic Leberʼs hereditary optic neuropathy: a prospective study using swept-source optical coherence tomography