1. Articles from Grace M. Richter

    1-9 of 9
    1. Advances in Ocular Imaging in Glaucoma (Textbook)

      Advances in Ocular Imaging in Glaucoma (Textbook)

      Serving as a practical guide to the ocular imaging modalities that are currently available to eye care providers for the care of glaucoma patients, this book provides information on advances in ocular imaging and their applications in the diagnosis and management of glaucoma. Each chapter introduces the imaging modality, highlight its strengths and weaknesses for clinical care, and discuss its integration into the clinical examination and decision-making process. The chapters also provide an in-depth description of the interpretation of images from each imaging modality. When appropriate, the chapters will summarize past and ongoing research and propose future research directions and ...

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    2. Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries

      Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries

      Precis: When comparing 4.5×4.5 mm to 6.0×6.0 mm optical coherence tomography angiography scans of the radial peripapillary capillaries (RPCs) for glaucoma diagnostic capability, there was a trend of 4.5 scans outperforming 6.0 scans, especially for inferior, nasal, and superior quadrants. Objectives: The main purpose of this study was to compare diagnostic ability of peripapillary vessel parameters from 4.5×4.5 mm (4.5) and 6.0×6.0 mm (6.0) spectral-domain optical coherence tomography angiography scans of the RPC in detecting primary open-angle glaucoma from nonglaucoma eyes. Methods: Consecutive patients ...

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    3. Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography

      Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography

      Purpose : To evaluate the relationship between angle dimensions assessed by gonioscopy or EyeCam and anterior segment optical coherence tomography (AS-OCT). Methods : Subjects aged 50 years or older were recruited from the Chinese American Eye Study (CHES). Each subject underwent a complete ocular exam, including gonioscopy, AS-OCT, and EyeCam. Angle closure was defined as three or more quadrants in which pigmented trabecular meshwork could not be visualized. Angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), trabecular iris angle (TIA), and scleral spur angle (SSA) were measured in each AS-OCT image. Results : 709 eyes (272 angle closure ...

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    4. Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma

      Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma

      Purpose : To compare the diagnostic ability of the vessel parameters in macular and peripapillary regions measured using spectral-domain optical coherence tomography angiography (SD-OCTA) in differentiating primary open-angle glaucoma (POAG) from healthy eyes. Methods : POAG patients and healthy subjects underwent 6 × 6-mm scans centered on the macula and optic nerve head. Commercially available automatic segmentation created en face images from SD-OCTA of the superficial retinal layer (SRL) of the macular (m) and peripapillary (cp) regions. Vessel area density (VAD), vessel skeleton density (VSD), vessel complexity index (VCI), and flux were calculated. Area under curve (AUC) statistics controlled for age and intereye ...

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    5. Peripapillary microvasculature in the retinal nerve fiber layer in glaucoma by optical coherence tomography angiography: focal structural and functional correlations and diagnostic performance

      Peripapillary microvasculature in the retinal nerve fiber layer in glaucoma by optical coherence tomography angiography: focal structural and functional correlations and diagnostic performance

      Purpose: To quantify peripapillary microvasculature within the retinal nerve fiber layer (RNFL) in primary open-angle glaucoma (POAG) and normal eyes, determine association of perfusion parameters with structural and functional measures, and report diagnostic accuracy of perfusion parameters. Patients and methods: POAG and normal patients underwent 6×6 mm2 optic nerve head scans (Angioplex optical coherence tomography angiography [OCTA]; Cirrus HD-OCT 5000) and Humphrey Field Analyzer II-i 24-2 visual field (VF) testing. Prototype software performed semiautomatic segmentation to create RNFL en face images and quantified vessel area density (VAD), vessel skeleton density (VSD), and vessel complexity index (VCI) in the optic ...

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    6. Structural and Functional Associations of Macular Microcirculation in the Ganglion Cell-inner Plexiform Layer in Glaucoma Using Optical Coherence Tomography Angiography

      Structural and Functional Associations of Macular Microcirculation in the Ganglion Cell-inner Plexiform Layer in Glaucoma Using Optical Coherence Tomography Angiography

      Purpose: To quantify retinal microvasculature within the macular ganglion cell-inner plexiform layer (GCIPL) in primary open angle glaucoma (POAG) and normal eyes, determine association of vessel parameters with structural and functional measures, and report diagnostic accuracy of vessel parameters. Methods: POAG and normal patients underwent 6▒mm×6▒mm macula scans (Angioplex TM optical coherence tomography angiography [OCTA]; Cirrus TM HD-OCT 5000); and Humphrey Field Analyzer II-i 24-2 visual field (VF) (Zeiss, Dublin, CA). Prototype software performed semi-automatic segmentation to create GCIPL en face images, and quantified vessel area density (VAD), vessel skeleton density (VSD), and vessel complexity index (VCI ...

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    7. The Promise of Optical Coherence Tomography Angiography in Glaucoma

      The Promise of Optical Coherence Tomography Angiography in Glaucoma

      Optical coherence tomography angiography (OCTA) studies in primary open-angle glaucoma have consistently demonstrated reduced microcirculation in the superficial optic nerve, 1 peripapillary retina, 2 , 3 and the macula 4 , 5 of glaucoma patients. These studies clearly demonstrate the superior resolution of OCTA compared with prior methods that were used to measure ocular blood flow (OBF) or its surrogates. How will OCTA help the glaucoma clinician now and in the future? What else must we learn before achieving more practical usefulness from OCTA for glaucoma? First, OCTA will supplement current glaucoma diagnostic tools to aid in the early detection of glaucoma ...

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    8. Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications

      Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications

      OCT has revolutionized the practice of ophthalmology over the past 10–20 years. Advances in OCT technology have allowed for the creation of novel OCT-based methods. OCT-Angiography (OCTA) is one such method that has rapidly gained clinical acceptance since it was approved by the FDA in late 2016. OCTA images are based on the variable backscattering of light from the vascular and neurosensory tissue in the retina. Since the intensity and phase of backscattered light from retinal tissue varies based on the intrinsic movement of the tissue (e.g. red blood cells are moving, but neurosensory tissue is static), OCTA ...

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    9. Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis

      Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis

      Purpose: To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error. Design: Observational, cross-sectional. Participants: In total, 180 normal eyes of 112 participants and 180 eyes of 138 participants with perimetric glaucoma from the Advanced Imaging for Glaucoma Study. Methods: Diagnostic variables evaluated from TD-OCT and FD-OCT were: disc area, rim area, rim volume, optic nerve head volume, vertical cup-to-disc ratio (CDR), and horizontal ...

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    1-9 of 9
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    Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications The Promise of Optical Coherence Tomography Angiography in Glaucoma Structural and Functional Associations of Macular Microcirculation in the Ganglion Cell-inner Plexiform Layer in Glaucoma Using Optical Coherence Tomography Angiography Peripapillary microvasculature in the retinal nerve fiber layer in glaucoma by optical coherence tomography angiography: focal structural and functional correlations and diagnostic performance Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries Advances in Ocular Imaging in Glaucoma (Textbook) Postdoctoral Openings in Biomedical Optics and Retinal Imaging Laboratory at University of Illinois at Chicago Devices and arrangements for performing coherence range imaging using a common path interferometer Scan error correction in low coherence scanning interferometry