1. Articles from Konstantin I. Maslov

    1-3 of 3
    1. Photoacoustic and optical coherence tomography of epilepsy with high temporal and spatial resolution and dual optical contrasts

      Photoacoustic and optical coherence tomography of epilepsy with high temporal and spatial resolution and dual optical contrasts

      Epilepsy mapping with high spatial and temporal resolution has great significance for both fundamental research on epileptic neurons and the clinical management of epilepsy. In this communication, we demonstrate for the first time in vivo epilepsy mapping with high spatial and temporal resolution and dual optical contrasts in an animal model. Through the variations of a depthresolved optical coherence tomography signal with optical scattering contrast, we observed that epileptic neuron activities modulated the optical refractive index of epileptic neurons and their surrounding tissue. Simultaneously, through neurovasculature coupling mechanisms and optical absorption contrast, we used photoacoustic signals to document the hemodynamic ...

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    2. Living Brain Optical Imaging: Technology, Methods and Applications

      Living Brain Optical Imaging: Technology, Methods and Applications

      Within the last few decades, optical imaging methods have yielded revolutionary results when applied to all parts of the central nervous system. The purpose of this review is to analyze research possibilities and limitations of several novel imaging techniques and show some of the most interesting achievements obtained by these methods. Here we covered intrinsic optical imaging, voltage-sensitive dye, photoacoustic, optical coherence tomography, near-infrared spectroscopy and some other techniques. All of them are mainly applicable for experimental neuroscience but some of them also suitable for the clinical studies.

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    3. In-vivo imaging of microcirculation using integrated photoacoustic and optical-coherence microscopy

      Photoacoustic imaging and optical coherence tomography have complementary imaging contrasts. Photoacoustic imaging is sensitive to optical absorption, thus is able to generate detailed maps of deep microvasculature in vivo. Optical coherence tomography exploits the optical scattering contrast, and can provide real-time, micrometer-resolution imaging of tissue. We integrate an optical-resolution photoacoustic microscopy and a spectral-domain optical coherence tomography into a single system. Our preliminary experiments showed that it could be a valuable imaging tool for microcirculation studies in vivo.
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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Washington University in St. Louis
    2. (3 articles) Konstantin I. Maslov
    3. (2 articles) Lihong V. Wang
    4. (2 articles) Li Li
    5. (1 articles) Harvard University
    6. (1 articles) University of Maryland
    7. (1 articles) Massachusetts General Hospital
    8. (1 articles) Geng Ku
    9. (1 articles) Thorlabs
    10. (1 articles) Fudan University
    11. (1 articles) UCLA
    12. (1 articles) University of Miami
    13. (1 articles) Capital Medical University
    14. (1 articles) VU University Amsterdam
    15. (1 articles) Srinivas R. Sadda
    16. (1 articles) Johannes F. de Boer
    17. (1 articles) Frank D. Verbraak
    18. (1 articles) Apollo Medical Optics
    19. (1 articles) Heidelberg Engineering
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