1. Articles from Long Li

    1-5 of 5
    1. Macrocalcification of intracranial vertebral artery may be related to in-stent restenosis: lessons learned from optical coherence tomography

      Macrocalcification of intracranial vertebral artery may be related to in-stent restenosis: lessons learned from optical coherence tomography

      Background: Calcification has been proven to be a marker of atherosclerosis and is related to an increased risk of ischemic stroke. Additionally, calcification was reported to be prevalent in patients with stenotic lesions of the intracranial vertebral artery. Thus, reliable imaging facilities for evaluating plaque calcification have remarkable significance in guiding stenting and predicting patient outcomes. Optical coherence tomography (OCT) has a unique advantage in its ability to detect calcium and to achieve three-dimensional volumetric calcium characterization. Methods: From March 2017 to September 2018, seven cases of calcified lesions with intracranial vertebral artery stenosis were investigated using OCT, before and ...

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    2. Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience

      Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience

      Background: Despite advances in non-invasive imaging, the characterization of atherosclerotic plaque remains superior with frequency-domain optical coherence tomography (FD-OCT) in the clinical coronary and experimental cerebrovascular literature. An assessment of the feasibility and safety of FD-OCT for intracranial atherosclerotic stenosis (ICAS) is desirable. Methods: We analyzed a cohort of all consecutive FD-OCT evaluations for ICAS performed at our institution from April 2017 to August 2018 (16 months) in patients who suffered from transient ischemic attack (TIA) or non-disabling stroke despite optimal medical management within 90 days of admission attributable to angiographically verified 70-99% stenosis of an intracranial artery. Results: Thirty-three ...

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    3. Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography

      Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography

      Background: Intracranial vertebral artery (V4 segment) stenosis quantification traditionally uses the narrowest stenosis diameter. However, the stenotic V4 lumen is commonly irregularly shaped. Optical coherence tomography (OCT) allows a more precise calculation of V4 geometry. We compared the narrowest diameter stenosis (DS), measured by digital subtraction angiography (DSA), with the area stenosis (AS), measured by OCT. We hypothesized that DS is the gold standard for measuring the degree of stenosis. Methods: Five neuroradiologists evaluated 49 stenosed V4 segments in a blinded protocol. V4 stenosis was measured in millimeters on DSA at its narrowest diameter. OCT was used to estimate the ...

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    4. Visualization of the Human Intracranial Vasa Vasorum In Vivo Using Optical Coherence Tomography

      Visualization of the Human Intracranial Vasa Vasorum In Vivo Using Optical Coherence Tomography

      The vasa vasorum are a specialized microvasculature that mainly arise from the adventitia and traverse the intimomedial layer of large arteries and veins. These are felt to serve as crucial routes of the delivery for trophic and nutritive factors, as well as regulatory signals. 1 Importantly, they also play a role in pathology via proliferation in atherosclerotic and hypertrophic intimomedia, as well as plaque hemorrhage and dissection via rupture. 2 In the setting of symptomatic vertebral artery stenosis, we report what is, to our knowledge, the first known in vivo visualization of the human native intracranial arterial vasa vasorum and ...

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    5. Evaluation of macular holes by optical coherence tomography in Chinese patients

      Evaluation of macular holes by optical coherence tomography in Chinese patients

      Aim: To evaluate the diagnostic significance of optical coherence tomography for macular holes. Materials and methods: From October 1999 to February 2000, forty six eyes of 40 patients with clinically diagnosed or suspected macular holes had optical coherence tomography performed via dilated pupils in both eyes. All images were measured and analyzed. Results: The optical coherence tomography technique showed lamellar macular holes in 11 eyes of 9 patients with partial neural epithelium defect. The average remaining retinal thickness of the macular area was 108 mm (standard deviation, 42.5 mm). Thirty eyes of 27 patients had full-thickness macular holes. The ...

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    1-5 of 5
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    Evaluation of macular holes by optical coherence tomography in Chinese patients Visualization of the Human Intracranial Vasa Vasorum In Vivo Using Optical Coherence Tomography Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience Macrocalcification of intracranial vertebral artery may be related to in-stent restenosis: lessons learned from optical coherence tomography Post-Doctoral and Graduate Student Research Positions at the University of Illinois Urbana-Champaign Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque PERSONALIZED CHARACTERISTICS OF MORPHOMETRIC AND FUNCTIONAL PARAMETERS OF RETINA IN ARTERIAL HYPERTENTION ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY-ANGIOGRAPHY DATA Coherence function-encoded optical palpation Systems, methods, and media for multiple reference arm spectral domain optical coherence tomography Monitoring dissolution of a dosage form in progress during dissolution by low coherence interferometry