1. Articles from Robert A. Bermel

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    1. Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

      Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

      Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive, high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by OCT facilitates a ‘window’ into not only local retinal pathology but also global neurodegenerative processes, recognised to be the principal substrates of disability accumulation in MS. While OCT measures in MS have been demonstrated to reflect visual function, inflammatory activity outside of the visual pathways, disability measures including the prediction of disability progression, whole brain atrophy, and the differential neuroprotective effects of disease-modifying therapies, debate continues regarding the clinical utility of OCT in everyday practice. This review presents ...

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    2. Optical Coherence Tomography for the Detection of Remote Optic Neuritis in Multiple Sclerosis

      Optical Coherence Tomography for the Detection of Remote Optic Neuritis in Multiple Sclerosis

      BACKGROUND AND PURPOSE Evidence of remote optic neuritis is often used to support a diagnosis of multiple sclerosis (MS). Optical coherence tomography (OCT) can provide qualitative and quantitative data on the retina, where the effects of optic neuritis can be seen. Our aim was to determine whether there is a quantitative difference in retinal structures in eyes with optic neuritis compared with those without, and which measures were best able to discriminate eyes with a history of optic neuritis from nonoptic neuritis eyes in MS patients. METHODS We performed a prospective cohort study of 30 MS-optic neuritis patients, 22 MS-nonoptic ...

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      Mentions: Peter K. Kaiser
    1-2 of 2
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  2. Topics in the News

    1. (1 articles) Johns Hopkins University
    2. (1 articles) Cleveland Clinic
    3. (1 articles) Peter K. Kaiser
    4. (1 articles) Yonsei University
    5. (1 articles) University of Kent
    6. (1 articles) Tianjin University
    7. (1 articles) University College London
    8. (1 articles) UCSD
    9. (1 articles) Adrian G. Podoleanu
    10. (1 articles) Jung-Sun Kim
    11. (1 articles) Dong Hoon Choi
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    Optical Coherence Tomography for the Detection of Remote Optic Neuritis in Multiple Sclerosis Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch's Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration Texture preservation and speckle reduction in poor optical coherence tomography using the convolutional neural network Research Assistant in Optical Coherence Tomography (OCT) to Image the Eye at University of Kent Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope Chronic Stent Recoil in Severely Calcified Coronary Artery Lesions. A Serial Optical Coherence Tomography Study Migrated remnant bioresorbable scaffolds in a left main bifurcation lesion: Insights from optical coherence tomography Longitudinal Monitoring of Flow-Diverting Stent Tissue Coverage After Implant in a Bifurcation Model Using Neurovascular High-Frequency Optical Coherence Tomography Foveal crack sign: an optical coherence tomography sign preceding macular hole after vitrectomy for rhegmatogenous retinal detachment Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice Optical coherence tomography characteristics of taxane-induced macular edema and other multimodal imaging findings